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2026
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OpenAlex
Junnan Liu, Wencheng Jiang, Xue Wang, Anca Azoitei et autres
BACKGROUND: Bladder cancer (BC) can be characterized clinically as either non-muscle-invasive (NMIBC) or muscle-invasive (MIBC). While NMIBC generally has a favorable prognosis, MIBC is characterized by high morbidity and mortality. Understanding the molecular determinants of tumor invasion is critical, yet research is …
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2026
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OpenAlex
Junnan Liu, Wencheng Jiang, Xue Wang, Anca Azoitei et autres
Additional file 8: SF8. Expression of EDNRB, MMP3 and PTGS2 in NMIBC, MIBC and correlation their mRNA levels to patient survival. A. EDNRB (ETA), MMP3, and PTGS2 (COX-2) mRNA levels in NMIBC versus MIBC in GSE13507 and GSE32894 datasets. The microarray datasets …
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2026
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OpenAlex
Junnan Liu, Wencheng Jiang, Xue Wang, Anca Azoitei et autres
Additional file 9: ST1. Table showing which candidate was identified in which well in the first and second EXTIM seeding. Red font indicates that no transmigration was observed in the second seeding.
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2026
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OpenAlex
Junnan Liu, Wencheng Jiang, Xue Wang, Anca Azoitei et autres
Additional file 12: ST4. The applications, advantages, and disadvantages of the Boyden chamber, ex vivo porcine bladder, and EXTIM are compared.
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2026
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OpenAlex
Junnan Liu, Wencheng Jiang, Xue Wang, Anca Azoitei et autres
Additional file 3: SF3. Results of Western blot experiments demonstrating shRNA-mediated downregulation of GJB3 or ORP3 in RT4-TP53DD cells. The Western blot results indicate ORP3 protein expression (A) in RT4-TP53DD cells with shScr, shORP3#1, and shORP3#2 and GJB3 protein expression (B) in …
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2026
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OpenAlex
Junnan Liu, Wencheng Jiang, Xue Wang, Anca Azoitei et autres
Additional file 7: SF7. ETA is expressed in invasive BC cell lines and inhibits their migratory and invasive capacities. (A) Relative ETA (EDNRA) and (B) ETB (EDNRB) mRNA expression levels quantified by qRT-PCR in RT4, B61, T24, UMUC3, and BFTC-905 cell lines. …
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2026
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OpenAlex
Junnan Liu, Wencheng Jiang, Xue Wang, Anca Azoitei et autres
Additional file 1: SF1. Control experiment showing that only UMUC3 cells but not RT4 cells transmigrate through the mouse bladder in the EXTIM A. Representative images illustrating the different transmigratory capacities of three different cell groups, RT4, UMUC3, and RT4:UMUC3-eGFP, in the …
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2026
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OpenAlex
Junnan Liu, Wencheng Jiang, Xue Wang, Anca Azoitei et autres
Additional file 11: ST3. Gene Ontology (GO-BP) enrichment analysis was performed via the Enrichr tool [63] ( https://maayanlab.cloud/Enrichr/ ).
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Junnan Liu, Wencheng Jiang, Xue Wang, Anca Azoitei et autres
Additional file 14: ST6. List of chemicals used for screening of compounds with detailed information.
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OpenAlex
Junnan Liu, Wencheng Jiang, Xue Wang, Anca Azoitei et autres
Additional file 8: SF8. Expression of EDNRB, MMP3 and PTGS2 in NMIBC, MIBC and correlation their mRNA levels to patient survival. A. EDNRB (ETA), MMP3, and PTGS2 (COX-2) mRNA levels in NMIBC versus MIBC in GSE13507 and GSE32894 datasets. The microarray datasets …
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Accès ouvert
2026
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OpenAlex
Junnan Liu, Wencheng Jiang, Xue Wang, Anca Azoitei et autres
Additional file 4: SF4. Determination of relative DDR1 mRNA levels via RT‒qPCR. A. The bar graph shows the relative DDR1, AZGP1 and STK19, STEAP3, and LAT mRNA levels in non/low-invasive BC cell lines (RT4 and BC61) as well as in highly invasive …
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2026
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OpenAlex
Junnan Liu, Wencheng Jiang, Xue Wang, Anca Azoitei et autres
Additional file 4: SF4. Determination of relative DDR1 mRNA levels via RT‒qPCR. A. The bar graph shows the relative DDR1, AZGP1 and STK19, STEAP3, and LAT mRNA levels in non/low-invasive BC cell lines (RT4 and BC61) as well as in highly invasive …
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