Hirotaka Haro

Cost-Effectiveness of Monotherapy versus Polypharmacy in Cervicobrachial Symptoms: A Nationwide Multicenter Analysis

Sadayuki Ito, Hiroaki Nakashima, Norimitsu Wakao, Takeo Furuya et autres

Introduction: Cervicobrachial symptoms are common causes of disability worldwide, yet the cost-effectiveness of combination therapy versus monotherapy remains unclear. In this nationwide multicenter study, we aimed to compare the economic value of multiple-drug therapy with that of monotherapy for cervicobrachial symptoms. Methods: …

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Maintaining clinical remission and preventing fractures are essential for preserving functional status over a 10-year period in patients with rheumatoid arthritis who have achieved Health Assessment Questionnaire-Disability Index remission: a retrospective cohort study

Kensuke Koyama, Tetsuro Ohba, Ryousuke Koizumi, Koki Watabe et autres

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Correlation between fracture pattern and chronological age and skeletal maturity in distal radial fractures in children

Masanori Wako, Tetsuhiro Hagino, Tetsuo Hagino, Jiro Ichikawa et autres

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Efficacy of Corticosteroid Addition to Selective Nerve Root Block for Lumbar Radiculopathy: A Multicenter Prospective Cohort Study

Jun Ouchida, Hiroaki Nakashima, Masayuki Miyagi, Gen Inoue et autres

Introduction: The addition of corticosteroids to selective nerve root block (SNRB) is widely practiced for lumbar radiculopathy, yet robust evidence regarding its efficacy for functional outcomes remains limited. We evaluated whether adding corticosteroids to local anesthetic in SNRB relieves functional disability and …

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Establishment and Preliminary Outcomes of a Nationwide Spine and Spinal Cord Surgery Registry in Japan: Analysis of 158,263 Cases in 2022

Hideyuki Arima, Chie Shimmura, Yosuke Shibata, Toshimi Aizawa et autres

Introduction: The Japanese Society for Spine Surgery and Related Research (JSSR) developed a national web-based registry system, integrating it with the Japanese Orthopaedic Association National Registry (JOANR/JSSR-DB) to systematically collect data on spinal and spinal cord surgeries and complications. This study aimed …

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Delayed Postoperative Spinal Epidural Hematoma After Thoracic OPLL Surgery: A Case Report and Literature Review

Hayato Takei, Tetsuro Ohba, Nobuki Tanaka, Kotaro Oda et autres

New axial pain with rapid neurological decline weeks after surgery for thoracic ossification of the posterior longitudinal ligament may signal delayed postoperative epidural hematoma. Immediate MRI and urgent decompression are critical. Consider occult clot-stabilization defects such as factor XIII deficiency when routine …

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Metastatic subcutaneous Ewing sarcoma mimicking a synchronous second primary neoplasm: a case description

Jiro Ichikawa, Koshi Akahane, Minori Tamai, Kojiro Onohara et autres

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Diagnostic challenge in retroperitoneal tumor by imaging

Jiro Ichikawa, Kojiro Onohara, Masanori Wako, Hirotaka Haro

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Imaging, clinical, and histopathological challenges in diagnosing retroperitoneal extraskeletal osteosarcoma

Jiro Ichikawa, Tomonori Kawasaki, Kojiro Onohara, Masanori Wako et autres

1 IntroductionExtraskeletal osteosarcoma (EO) is a malignant mesenchymal neoplasm characterized by the production of osteoid tissue without connection to the skeletal system (1). EO is rare and accounts for approximately 6% of all osteosarcomas. EO frequently occurs in middle-aged and older individuals …

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Assessment of Fall Risk and Adverse Events Among General Ward Inpatients at a Regional General Hospital in Japan

Tetsuo Hagino, Tetsuhiro Hagino, Masanori Wako, Satoshi Ochiai et autres

INTRODUCTION: Falls among hospitalized patients pose a significant concern for patient safety, influencing quality of life, mortality, and healthcare costs. This study aimed to assess the incidence of falls and related adverse events among general ward inpatients at a regional general hospital …

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Diagnostic challenges in imaging and immunohistopathological profiles in extraskeletal osteosarcoma

Jiro Ichikawa, Tomonori Kawasaki, Kojiro Onohara, Kaoru Aoki et autres

This correspondence addresses the article published by Nie et al. titled "Primary extraskeletal osteosarcoma of sigmoid mesocolon: a case report and a review of the literature". Their report highlighted an extremely rare case of extraskeletal osteosarcoma (EO) in the sigmoid mesocolon that …

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The novel role of MDM2 in the diagnosis and treatment of dedifferentiated liposarcoma

Jiro Ichikawa, Tomonori Kawasaki, Kojiro Onohara, Satoshi Kanno et autres

Dedifferentiated liposarcoma (DDLPS) is a subtype of liposarcoma that frequently occurs in the retroperitoneum. Approximately 10% of atypical lipomatous tumors/well-differentiated liposarcomas (ALTs/WDLPSs) are dedifferentiated, with one risk factor being a retroperitoneal location (1). DDLPS exhibits heterogeneous differentiation, including myogenic or osteosarcomatous/chondrosarcomatous elements …

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