Laura Nasarre

Pre-existing cell populations with cytotoxic activity against SARS-CoV-2 in people with HIV and normal CD4/CD8 ratio previously unexposed to the virus

Guiomar Casado‐Fernández, Juan Cantón, Laura Nasarre, Fernando Ramos-Martín et autres

Introduction: HIV-1 infection may produce a detrimental effect on the immune response. Early start of antiretroviral therapy (ART) is recommended to preserve the integrity of the immune system. In fact, people with HIV (PWH) and normal CD4/CD8 ratio appear not to be …

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Development of Innovative Antiatherosclerotic Peptides through the Combination of Molecular Modeling and a Dual (Biochemical‐Cellular) Screening System

Aleyda Benitez‐Amaro, Chiara Pallara, Laura Nasarre, R. C. S. Ferreira et autres

Abstract Cardiovascular disease (CVD) is a leading cause of death worldwide. Approximately 60% of patients treated with low‐density lipoprotein (LDL)‐lowering drug treatments, with on‐target plasma cholesterol levels, are still suffering clinical acute ischemic events. Mechanisms, such as LDL aggregation, underlie extracellular and …

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Low-density lipoprotein receptor-related protein 1 deficiency in cardiomyocytes reduces susceptibility to insulin resistance and obesity

Aleyda Benitez‐Amaro, Elena Revuelta‐López, Olga Bornachea, Lídia Cedó et autres

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Plasma circular RNA hsa_circ_0001445 and coronary artery disease: Performance as a biomarker

David Viladés, Pablo Martínez‐Camblor, Andreu Ferrero‐Gregori, Christian Bär et autres

Abstract The role of circular RNAs (circRNAs) as biomarkers remains poorly characterized. Here, we investigated the performance of the circRNA hsa_circ_0001445 as a biomarker of coronary artery disease (CAD) in a real‐world clinical practice setting. Plasma hsa_circ_0001445 was measured in a study …

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Immunization with the Gly1127-Cys1140 amino acid sequence of the LRP1 receptor reduces atherosclerosis in rabbits. Molecular, immunohistochemical and nuclear imaging studies

Olga Bornachea, Aleyda Benitez‐Amaro, Àngela Vea, Laura Nasarre et autres

Background: The LRP1 (CR9) domain and, in particular, the sequence Gly 1127 -Cys 1140 (P3) plays a critical role in the binding and internalization of aggregated LDL (agLDL).We aimed to evaluate whether immunization with P3 reduces high-fat diet (HFD)-induced atherosclerosis.Methods: Female New …

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Micrornas As Circulating Biomarkers Of Epicardial Fat Volume: A Multidetector Computed Tomography Study

David de Gonzalo‐Calvo, David Viladés, Pablo Martínez‐Camblor, Àngela Vea et autres

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Plasma microRNA Profiling Reveals Novel Biomarkers of Epicardial Adipose Tissue: A Multidetector Computed Tomography Study

David de Gonzalo‐Calvo, David Viladés, Pablo Martínez‐Camblor, Àngela Vea et autres

Epicardial adipose tissue (EAT) constitutes a novel parameter for cardiometabolic risk assessment and a target for therapy. Here, we evaluated for the first time the plasma microRNA (miRNA) profile as a source of biomarkers for epicardial fat volume (EFV). miRNAs were profiled …

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Circulating micro RNA s in suspected stable coronary artery disease: A coronary computed tomography angiography study

David de Gonzalo‐Calvo, David Viladés, Pablo Martínez‐Camblor, Àngela Vea et autres

OBJECTIVES: To explore the diagnostic performance of circulating microRNAs (miRNAs) as biomarkers in patients with suspected stable coronary artery disease (CAD). METHODS: Plasma samples were collected from 237 consecutive patients referred for coronary computed tomography angiography (CCTA). Presence, extension and severity of …

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Molecular basis for the protective effects of low-density lipoprotein receptor-related protein 1 (LRP1)-derived peptides against LDL aggregation

Aleyda Benitez‐Amaro, Chiara Pallara, Laura Nasarre, Andrea Rivas-Urbina et autres

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Identification of new biophysical markers for pathological ventricular remodelling in tachycardia‐induced dilated cardiomyopathy

Aleyda Benitez‐Amaro, V. Samouillan, Esther Jorge, Jany Dandurand et autres

Our aim was to identify biophysical biomarkers of ventricular remodelling in tachycardia-induced dilated cardiomyopathy (DCM). Our study includes healthy controls (N = 7) and DCM pigs (N = 10). Molecular analysis showed global myocardial metabolic abnormalities, some of them related to myocardial …

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Radiological Image of the Tyrosine Kinase Inhibitors Response of Metastatic Renal Cell Carcinoma

Laura Nasarre

Oncology International Journal is dedicated to publish the contributions on all aspects of experimental and clinical cancer research. CTOIJ is a multidisciplinary, Open Access, peer reviewed journal accepts Research, Review Articles, Short Communications

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Radiological pulmonary manifestations of scleroderma and synchronic pneumoconiosis.

A. Narbona Díez, P. Trallero, Laura Nasarre, Corrales Hernández Jj et autres

Poster: ECR 2018 / C-0339 / Radiological pulmonary manifestations of scleroderma and synchronic pneumoconiosis. by: A. Narbona Diez , P. Trallero , L. Ceron Nasarre, J. Hernandez, J. C. Aparicio Lopez, X. Pruna; Granollers/ES