Yanhong Luo

Development and validation of an interpretable ultrasound radiomics model for benign and malignant classification of breast lesions: a multicenter large-sample study

Di Zhang, Wen-Wu Lu, Xia-Chuan Qin, Wang Zhou et autres

OBJECTIVES: To develop and validate a combined ultrasound-based radiomics-clinical model for differentiating benign and malignant breast lesions. MATERIALS AND METHODS: A total of 3142 patients from eight hospitals between February 2012 and September 2024 were included in this multicenter retrospective development and …

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Deciphering the gonadal cell atlas of Monopterus albus and cell fate during sex reversal based on single-cell RNA sequencing

Lingbo Yi, Fuyun Zhu, Lun Liu, Yanhong Luo et autres

The Monopterus albus serves as a unique model for studying sex reversal, transitioning naturally from female to male. However, the origins of male germline stem cells (GSCs) and the roles of somatic cells during sex reversal remain poorly understood. We performed single-cell …

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Serum response factor aggravates acute kidney injury via the NIK/NF-κB signaling in LPS-treated HK-2 cells

Qun Pan, Qin Yu, Yanhong Luo, Ronghua Yang

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Multi-omics data integration for enhanced cancer subtyping via interactive multi-kernel learning

Cao Hong-yan, Tong Wang, Zhaoyang Xu, Xin Zhao et autres

Cancer is a highly heterogeneous disease characterized by complex molecular changes. Subtypes identified through multi-omics data hold significant promise for improving prognosis and facilitating personalized precision treatment. Recent multi-omics integration methods have mostly focused on capturing complementary information from different data types, …

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The Role of Haptic Interaction in Embodied Extended-Reality Learning: A Three-Level Meta-Analysis

Peidi Gu, Yihang Li, Hailin Ji, Yiran Zhang et autres

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SpatialESD: spatial ensemble domain detection in spatial transcriptomics

Hongyan Cao, Gaiqin Liu, Jingyi Xia, Tong Wang et autres

Abstract Spatial transcriptomics (ST) measures gene expression while preserving spatial context within tissues. One of the key tasks in ST analysis is spatial domain detection, which remains challenging due to the complex structure of ST data and the varying performance of individual …

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Mechanisms of T‑cell metabolic reprogramming in the microenvironment of acute myeloid leukemia and its therapeutic potential (Review)

Yanhong Luo, Jie Luo, Min Jae Yang, Xueya Zhao

Acute myeloid leukemia (AML) is an aggressive hematological malignancy that is often resistant to conventional therapies. The present narrative review discusses on the role of T cell metabolic reprogramming in the AML tumor microenvironment (TME), which markedly impacts the effectiveness of immunotherapy. …

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[Clinical application of single-balloon and double-balloon enteroscopy in pediatric small bowel diseases: a retrospective study of 576 cases].

Can-Lin Li, Jie‐Yu You, Yanhong Luo, Hongjuan Ouyang et autres

OBJECTIVES: To evaluate the effectiveness of single-balloon and double-balloon enteroscopy in diagnosing pediatric small bowel diseases and assess the diagnostic efficacy of computed tomography enterography (CTE) for small bowel diseases using enteroscopy as the reference standard. METHODS: =119), and the clinical data …

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Islanding Strategy for Smart Grids Oriented to Resilience Enhancement and Its Power Supply Range Optimization

Yanhong Luo, Wenchao Meng, Xi Zhu, A. I. Elombo et autres

With the increasing prevalence of distributed generators, islanded operation based on distributed generation is considered a vital means to enhance the reliability and resilience of smart grids. This paper investigates the main factors in islanding partition of smart grids and establishes a …

Integrating Mendelian randomization and multi-transcriptomic analyses to unveil the genetic association risk of regulatory T cell-mediated free cholesterol and gastric cancer

Fanyu Peng, Haitao Liu, Yesong Guo, Jing Wen et autres

BACKGROUND: Evidence from observational studies suggests an association between free cholesterol and gastric cancer. Immune cells play a crucial role in the tumor microenvironment of gastric cancer, and free cholesterol can influence immune cells in various ways, thereby impacting gastric cancer. The …

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Change in depressive symptom scores to assess the risk of new-onset dual sensory impairment in middle-aged and older adults: a nationwide cohort study

Jiang Wang, Lanzhi Duan, Rui Zeng, Fayi Xie et autres

Background: Evidence of the association between change in depressive symptom scores and new-onset dual sensory impairment (DSI) remain underexplored. We aimed to investigate the relationship between depressive symptom scores and the risk of new-onset DSI in middle-aged and older adults. Methods: The …

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Diagnostic interval of inflammatory bowel disease in Chinese children and its relationship with growth parameters: a retrospective study

Juan Zhou, BinRong Chen, Zhicheng Wang, Li Liu et autres

Background: Delayed diagnosis of inflammatory bowel disease (IBD) is common in Europe and North America, with limited research in Asia. We aimed to investigate factors influencing delayed diagnosis of IBD in Chinese children and the impact of delayed diagnosis on growth. Methods: …

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