Nina Barner‐Rasmussen

Primaarinen sklerosoiva kolangiitti : Epidemiologia, ennuste, liitännäissairaudet ja kuolleisuus

Nina Barner‐Rasmussen

Background: Primary Sclerosing Cholangitis (PSC) is a rare, chronic liver disease characterized by inflammation and fibrosis of the bile ducts, often leading to liver cirrhosis and, eventually, liver failure. There is an increased risk of malignancy, especially hepatobiliary malignancy. Despite significant morbidity, …

Surveillance of primary sclerosing cholangitis – a comparison of scheduled or on-demand ERCP with annual MRI surveillance: a multicenter study

Nina Barner‐Rasmussen, Antonio Molinaro, Bregje Mol, Cyriel I. J. Ponsioen et autres

Background: Primary sclerosing cholangitis (PSC) is associated with a high risk of hepatobiliary malignancy, especially cholangiocarcinoma (CCA). There are no good tumor markers to screen for CCA, and current recommendations for PSC monitoring are mainly based on expert opinions. The optimal strategy …

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Comparison of Endoscopic Ultrasound and CT Scan in the Diagnosis of Esophageal Duplication Cysts

Eve Ronkainen, Nina Barner‐Rasmussen, Kirsi Volmonen, Martti A. Färkkilä et autres

BACKGROUND AND AIM: Esophageal duplication cysts (EDCs) are rare congenital malformations, often discovered incidentally during endoscopy or on computed tomography (CT) scans. The role of endoscopic ultrasound (EUS) and CT scan in the diagnosis of these lesions and indications for surgical treatment …

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The new definition of dominant stricture in primary sclerosing cholangitis: Prevalence and clinical significance

Mathias Thylin, Martti A. Färkkilä, Hannu Kautiainen, Nina Barner‐Rasmussen et autres

BACKGROUND AND AIMS: A new definition of dominant stricture (NDS) has recently been defined for patients with primary sclerosing cholangitis (PSC). Prevalence and clinical features of this, compared to traditional dominant stricture (TDS), have not been reported. METHODS: In this single-centre longitudinal …

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The role of serology, liver function tests and imaging in screening of primary sclerosing cholangitis: the HelPSCreen score

Nina Barner‐Rasmussen, Nelli Sjöblom, Johanna T. Arola, Sonja Boyd et autres

OBJECIVES: At present, no sensitive or specific screening test exists for primary sclerosing cholangitis (PSC). PSC screening is mainly based on elevated alkaline phosphatase (ALP) in patients with inflammatory bowel disease (IBD). We aimed to produce a screening score based on laboratory …

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Dominant strictures in patients with primary sclerosing cholangitis: comparison between old and new definition

Andrea Tenca, Hannu Kautiainen, Mathias Thylin, Lauri Puustinen et autres

Occupational radiation dose from gastrointestinal endoscopy procedures with special emphasis on eye lens doses in endoscopic retrograde cholangiopancreatography

Touko T. Kaasalainen, A. Pekkarinen, Leena Kylänpää, Mia Rainio et autres

Abstract Background and study aims Endoscopic retrograde cholangiopancreatography (ERCP) procedures may result in remarkable radiation doses to patients and staff. The aim of this prospective study was to determine occupational exposures in gastrointestinal endoscopy procedures, with a special emphasis on eye lens …

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Novel screening test for primary sclerosing cholangitis: the role of serology, liver function tests, histology and radiology

Nina Barner‐Rasmussen, Nelli Sjöblom, Hannu Kautiainen, Johanna T. Arola et autres

Risk factors, epidemiology and prognosis of cholangiocarcinoma in Finland

Nina Barner‐Rasmussen, ­Eero Pukkala, Kishor Hadkhale, Martti A. Färkkilä

BACKGROUND: Cholangiocarcinoma (CCA) is a cancer arising from the intra- and extrahepatic bile ducts. The early stages are often asymptomatic, CCA is frequently diagnosed in an advanced stage and the prognosis of CCA is often dismal. OBJECTIVE: Our objective was to estimate …

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Epidemiology, risk of malignancy and patient survival in primary sclerosing cholangitis: a population-based study in Finland

Nina Barner‐Rasmussen, ­Eero Pukkala, Airi Jussila, Martti A. Färkkilä

Background: There are only a few and mostly small population-based epidemiological studies of primary sclerosing cholangitis (PSC).Objective: We aimed to estimate prevalence and incidence rates of PSC, and survival and malignancy risk for PSC patients in a large population-based study.Methods: We retrieved …

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Incidence, prevalence, and causes of death of patients with autoimmune hepatitis: A nationwide register-based cohort study in Finland

Lauri Puustinen, Nina Barner‐Rasmussen, ­Eero Pukkala, Martti A. Färkkilä

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Incidence and prevalence of Primary Sclerosing Cholangitis in a population-based cohort in Finland

Nina Barner‐Rasmussen, Martti A. Färkkilä