Ömer Faruk Alakuş

Hepatic fibrosis severity assessed by FIB-4 index is independently associated with reduced kidney function in patients with metabolic dysfunction-associated steatotic liver disease: a nationwide multicenter study from Türkiye

Hilmi Erdem Sümbül, Ali Kırık, Selcuk Yaylaci, Alihan Oral et autres

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Association Between Atherogenic Indices and the Triglyceride–Glucose Index in Individuals with Obesity

Ömer Faruk Alakuş, Jehat Kılıç, İhsan Solmaz

Objective: Atherogenic indices such as the plasma atherogenic index (AIP) and Castelli ratios provide valuable information about cardiometabolic risk. The triglyceride-glucose (TyG) index, a metabolic indicator of insulin resistance, has also been studied in relation to many metabolic disorders in recent years …

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Delayed graft function and its impact on short- and long-term outcomes after kidney transplantation

Jehat Kiliç, Rengin ESEN, Caner Varhan, Ömer Faruk Alakuş et autres

INTRODUCTION: Kidney transplantation is an effective treatment for end-stage renal disease, markedly improving survival and quality of life. However, delayed graft function (DGF) remains a notable early post-transplant complication. This study examine the impact of DGF on mortality, hypertension, graft survival, and …

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Limited Predictive Performance of Systemic Inflammatory Indices in Acute Pancreatitis Severity

Mehmet Serdar Yıldırım, Sedat Çiçek, Jehat Kılıç, Selman Çetin et autres

Background/Objectives: Acute pancreatitis (AP) is a heterogeneous disease with outcomes ranging from mild to severe. Early risk stratification is essential, but commonly used scoring systems are often complex for routine use. This study aimed to evaluate the predictive value of systemic inflammatory …

Glycemic Profiles of a Nation: Findings from Türkiye’s World Diabetes Day Screening Study

Nizameddin Koca, Yasin Şahintürk, Kubilay Issever, İsmail Demir et autres

Objective: To determine the prevalence of dysglycemia, including impaired glucose tolerance (IGT) and newly diagnosed diabetes mellitus (NDDM), in individuals visiting healthcare centers across Türkiye on World Diabetes Day and to assess the associated demographic and clinical risk factors.Methods: This multicenter cross-sectional …

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The role of lipid-derived indices in patients with MASLD in Turkey: a nationwide, multicenter cross-sectional study

İhsan Solmaz, Ali Kırık, İsmail Demir, Oğuzhan Sıtkı Dizdar et autres

To investigate the role of lipid-derived indices—the monocyte-to-HDL cholesterol ratio (MHR), visceral adiposity index (VAI), atherogenic index of plasma (PAI), and cardiometabolic index (CMI)—in determining hepatic steatosis and fibrosis among patients with metabolic dysfunction-associated steatotic liver disease (MASLD) across Turkey. This nationwide, …

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A Novel Approach to Determining Bone Loss Through Serum Uric Acid Levels: A Retrospective Multicenter Cohort Analysis

Ahmet Aydin, Turkan Pasali Kilit, Seher Kır, Eşref Araç et autres

Background: Osteoporosis has a rising global incidence and social burden. Serum uric acid’s dual roles in oxidative stress and inflammation may influence bone health, but findings are inconsistent and require further research. This study aimed to evaluate the relationship between SUA levels …

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Orlistat Therapy Significantly Reduces the Fatty Liver Index in Patients with Obesity: A Retrospective Cohort Study

Öznur Önen, İhsan Solmaz, Jehat Kılıç, Ömer Faruk Alakuş et autres

Objective: Metabolic dysfunction–associated steatotic liver disease (MASLD; formerly termed nonalcoholic fatty liver disease [NAFLD]) is a leading cause of chronic liver disease and related morbidity. Orlistat, a lipase inhibitor that reduces fat absorption, is used for weight loss. This study aimed to …

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Clinical Utility of the Triglyceride–Glucose Index in Assessing Hepatic Steatosis Severity Within the MASLD Spectrum

Ömer Faruk Alakuş, İhsan Solmaz, Jehat KILIC, Sedat Çiçek

Background/Objectives: The global increase in metabolic dysfunction-associated steatotic liver disease underscores the need for accessible and reliable markers to assess hepatic steatosis. The triglyceride–glucose (TyG) index, derived from fasting plasma glucose and triglyceride levels, has emerged as a practical surrogate marker of …

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Red cell distribution width and mean platelet volume as mortality markers in patients with COVID-19: a retrospective cohort study

Jehat KILIC, Ömer Faruk Alakuş, İhsan Solmaz

INTRODUCTION: This study investigates RDW and MPV as simple, cost-effective markers linked to increased mortality in COVID-19, highlighting their potential prognostic value in viral infections. METHODS: This retrospective observational study examined hospitalized COVID-19 patients from 2020 to 2022, assessing clinical outcomes such …

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The Impact of Body Mass Index and Nutritional Status on Cardiac Electrophysiological Balance Using ICEB and ICEBc: A Cross-Sectional Approach

Fethullah Kayan, Ömer Faruk Alakuş, Mihriban Elçiçek, Serdar Söner et autres

Background: The Index of Cardiac Electrophysiological Balance (ICEB) has emerged as a electrocardiographic marker reflecting the equilibrium between ventricular depolarization and repolarization. Although obesity is known to alter cardiac electrophysiology, the combined influence of body mass index (BMI) and objective nutritional status …

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Inflammatory Indices as Markers of Vascular and Organ Involvement in Behçet’s Disease

Jehat Kılıç, Gülşah Yamancan, Yusuf Hakan Dogan, Sümeyye Şahin et autres

Background: Behçet’s disease is a multisystem inflammatory disorder with a variable clinical course. This study evaluated the association between inflammatory indices, clinical involvement, and mortality. Methods: This retrospective study included 444 patients with BD. Clinical characteristics and laboratory data were systematically retrieved …

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