Qiangfei Su

Ameliorating ischemic stroke by systematically screening natural polyphenols to counteract the dual effects of AMPK activation in microglia

Jingwei Liu, Jian Wang, huan Liu, Luyao Zhu et autres

hk, cn (code pays fourni par la source)

Correction to “Sericin Nerve Guidance Conduit Delivering Therapeutically Repurposed Clobetasol for Functional and Structural Regeneration of Transected Peripheral Nerves”

Lei Zhang, Wen Yang, Hongjian Xie, Hui Wang et autres

Bioactive Silk Sericin/Bioceramic Nerve Guidance Conduit for Effective Repair of Long‐Gap Transected Peripheral Nerve Injury through Regulating Schwann Cells (Adv. Sci. 38/2025)

Qiangfei Su, Jian Wang, Yu Song, Zhaowenbin Zhang et autres

Bioactive Silk Sericin In article number 2507241, Zheng Wang, Jiang Chang, Lin Wang, and co-workers develop a novel artificial nerve guidance conduit that integrates silk sericin and bioceramics for long-gap peripheral nerve repair. This work highlights the synergistic effect of silk sericin …

Bioactive Silk Sericin/Bioceramic Nerve Guidance Conduit for Effective Repair of Long‐Gap Transected Peripheral Nerve Injury through Regulating Schwann Cells

Qiangfei Su, Jian Wang, Yu Song, Zhaowenbin Zhang et autres

Schwann cells are pivotal in generating a pro-regenerative microenvironment for long-gap peripheral nerve injury (PNI) repair via their orchestrated behaviors, including cell migration, proliferation, and secretion. Bioceramics can release bioactive ions to regulate "repair" cells for regenerating damaged tissues. Herein, bioceramic akermanite …

hk, cn (code pays fourni par la source)

Living photosynthetic micro/nano-platforms: Engineering unicellular algae for biomedical applications

Jian Wang, Haozhe Li, Qiangfei Su, Jingwei Liu et autres

The burgeoning field of algal biomedicine capitalizes on evolutionarily refined biological systems to address critical challenges in therapeutic delivery and tissue regeneration. As autotrophic biosystems, unicellular algae uniquely possess multi-functions, including oxygen generation, dynamic motility, fluorescence imaging, and programmable biosynthesis. Their photosynthetic …

hk, cn (code pays fourni par la source)

A materiobiology-inspired sericin nerve guidance conduit extensively activates regeneration-associated genes of Schwann cells for long-gap peripheral nerve repair

Xiakeerzhati Xiaohalati, Jian Wang, Qiangfei Su, Jingwei Liu et autres

hk, cn (code pays fourni par la source)

A Bioinspired Manganese‐Organic Framework Ameliorates Ischemic Stroke through its Intrinsic Nanozyme Activity and Upregulating Endogenous Antioxidant Enzymes

Jian Wang, Yang Wang, Xiakeerzhati Xiaohalati, Qiangfei Su et autres

Following stroke, oxidative stress induced by reactive oxygen species (ROS) aggravates neuronal damage and enlarges ischemic penumbra, which is devastating to stroke patients. Nanozyme-based antioxidants are emerging to treat stroke through scavenging excessive ROS. However, most of nanozymes cannot efficiently scavenge ROS …

hk, cn (code pays fourni par la source)

A Degradable and Biocompatible Supercapacitor Implant Based on Functional Sericin Hydrogel Electrode

Qiying Lv, Xiaoye Li, Xin Tian, Daan Fu et autres

Abstract Implantable power sources face great challenges in balancing multiple factors including high performance, biocompatibility, mechanical properties for soft tissue fit, and biodegradability. Toward this goal, a simple and feasible method is proposed to prepare implantable a hydrogel‐based supercapacitor (SC). Specially, a …

cn, ro, hk (code pays fourni par la source)

Oxygen-Generating Cyanobacteria Powered by Upconversion-Nanoparticles-Converted Near-Infrared Light for Ischemic Stroke Treatment

Jian Wang, Qiangfei Su, Qiying Lv, Bo Cai et autres

Stroke is one of most common causes of death and disability. Most of neuroprotective agents fail to rescue neurons from cerebral ischemic insults, mainly because of targeting downstream cascading events, such as excitotoxicity, oxidative and nitrosative stress, and inflammation, rather than improving …

hk, cn (code pays fourni par la source)

Injectable silk sericin scaffolds with programmable shape-memory property and neuro-differentiation-promoting activity for individualized brain repair of severe ischemic stroke

Jian Wang, Xiaolin Li, Yu Song, Qiangfei Su et autres

Severe ischemic stroke damages neuronal tissue, forming irregular-shaped stroke cavities devoid of supporting structure. Implanting biomaterials to provide structural and functional support is thought to favor ingrowth of regenerated neuronal networks. Injectable hydrogels capable of in situ gelation are often utilized for …

hk, cn (code pays fourni par la source)

Sericin Nerve Guidance Conduit Delivering Therapeutically Repurposed Clobetasol for Functional and Structural Regeneration of Transected Peripheral Nerves

Lei Zhang, Wen Yang, Hongjian Xie, Hui Wang et autres

Peripheral nerve injury often causes significant function loss. Autologous nerve grafting as a gold-standard repair strategy for treating such an injury is limited by donor nerve supply. Tissue-engineered nerve guidance conduits (TENGCs) as a promising alternative for autografting are challenged by large …

hk, cn (code pays fourni par la source)