Accès ouvert
2024
preprint
OpenAlex
Bo Zhu, Michael D. Lane, Joshua A. Baller, Pratik Jagtap et autres
Abstract Protease enzymes are of great importance in medicine, industry, and as research tools. Despite the crucial need for detailed knowledge of their proteolytic cleavage specificity, many proteases are poorly characterized. We present a method for fully characterizing the cleavage specificity of …
jp, us
(code pays fourni par la source)
2024
article
OpenAlex
Adam M. Lee, Paul Thuras, Joshua A. Baller, Chuan Jiao et autres
us, fr
(code pays fourni par la source)
2022
conference-paper
OpenAlex
Joshua A. Baller, Christine Henzler, James C. Wilgenbusch
The research cyberinfrastructure community has long recognized challenges recruiting, developing, retaining and scaling a strong workforce given the irregular cycle of sponsored research projects and institutional initiatives. The challenges are myriad, and across academic institutions, often vary based on the particular route …
us
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Mark D. Jankowski, David J. Fairbairn, Joshua A. Baller, Benjamin M. Westerhoff et autres
A major challenge in ecotoxicology is accurately and sufficiently measuring chemical exposures and biological effects given the presence of complex and dynamic contaminant mixtures in surface waters. It is impractical to quantify all chemicals in such matrices over space and time, and …
us
(code pays fourni par la source)
2021
conference-abstract
OpenAlex
Timothy K. Starr, Shobhana Talukdar, Zenas Chang, Jason Cepela et autres
Abstract Background: Women with ovarian cancer suffer from a high rate of mortality due to the development of chemotherapy resistance. To better understand the mechanisms of chemotherapy resistance we initiated a prospective study of women with ovarian cancer, which we refer to …
us
(code pays fourni par la source)
2020
article
OpenAlex
Alexandra Schefter, Timothy K. Starr, Saurav Talukdar, Z. Chang et autres
us
(code pays fourni par la source)
2020
conference-abstract
OpenAlex
Boris Winterhoff, Shobhana Talukdar, Zenas Chang, Jason Cepela et autres
Abstract A majority of women diagnosed with ovarian cancer will relapse after treatment, and most of these recurrent cancers will become resistant to standard chemotherapies. To better understand the mechanisms of chemotherapy resistance, we have initiated a prospective study to comprehensively analyze …
us
(code pays fourni par la source)
Accès ouvert
2019
conference-paper
OpenAlex
James C. Wilgenbusch, Carla Bates, Lisa Johnston, Joshua A. Baller et autres
Faced with escalating expenses related to data storage needs and a capable set of on campus storage service providers, the University of Minnesota (UMN) developed a comprehensive framework to better address current and emerging challenges and opportunities brought by data intensive research. …
us
(code pays fourni par la source)
2019
conference-paper
OpenAlex
Joshua A. Baller, Thomas J. Y. Kono, Adam Herman, Ying Zhang
Progressive decreases in the cost of DNA sequencing have contributed to a decades-long exponential increase in the production of new sequencing datasets. The processing of these datasets has in turn led biology, a field that has traditionally relied on local "lab" servers …
us
(code pays fourni par la source)
2019
article
OpenAlex
Locke Uppendahl, Z. Chang, A. Grad, W. Lee et autres
us
(code pays fourni par la source)
Accès ouvert
2018
article
OpenAlex
Nicholas J. Baltes, Paul Atkins, Elida R. Kirkland, Yong Zhang et autres
us, cn
(code pays fourni par la source)
Accès ouvert
2018
article
OpenAlex
Jennifer L. Dale, Kenneth B. Beckman, Julia L. E. Willett, Jennifer L. Nilson et autres
The robust ability of Enterococcus faecalis to survive outside the host and to spread via oral-fecal transmission and its high degree of intrinsic and acquired antimicrobial resistance all complicate the treatment of hospital-acquired enterococcal infections. The conserved E. faecalis core genome serves …
us
(code pays fourni par la source)