Accès ouvert
2026
preprint
OpenAlex
Yo-Taro Shirai, Jerrold Michael Ward, Yoshinori Takizawa, Huaitian Liu et autres
Abstract Many factors including ionizing radiation and iodine deficiency are known to increase thyroid carcinogenesis risk. Our dataset analysis of The Cancer Genome Atlas (TCGA) showed that lower mRNA expression of NK2 homeobox 1 ( NKX2-1 ) transcription factor, a master regulator …
jp, us
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Accès ouvert
2025
article
OpenAlex
Kunihiko Takahashi, Seiji Yasumura, Hideto Takahashi, Tomoki Nakaya et autres
BACKGROUND: In October 2011, the Fukushima prefectural government started a thyroid ultrasound examination (TUE) as part of the Fukushima Health Management Survey following the Fukushima Daiichi Nuclear Power Plant accident. The proportion of examinees is an important factor when interpreting the results. …
jp
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Accès ouvert
2025
article
OpenAlex
Satoshi Suzuki, Masanori Nagao, Natsuki Nagamine, Yurie Kobashi et autres
The ectopic intrathyroidal thymus (EIT) is located anywhere in the thyroid gland along the developmental pathway of thymic descent due to thymic migration during embryogenesis. Ultrasonographic findings of papillary thyroid carcinoma (PTC) resemble those of EIT, which is frequently found in children. …
jp
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Accès ouvert
2024
article
OpenAlex
Tetsuya Ohira, Masanori Nagao, Fumikazu Hayashi, Hiroki Shimura et autres
CONTEXT: Examining how overweight/obesity impacts thyroid nodule development in children and adolescents by sex and age allows speculation on the mechanism. OBJECTIVE: We examined whether overweight/obesity in children and adolescents is associated with thyroid nodule development by sex and age. METHODS: Approximately …
jp
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2024
article
OpenAlex
Akira Takama, Manabu Iwadate, Shigeyuki Tsukita, Hiromichi Ohira
Cancer of unknown primary is a class of malignant tumors, histologically identified as metastatic lesions whose primary origin is unknown despite adequate investigations for the primary tumor. Although the prognosis of cancer of unknown primary is generally poor, here, we report our …
jp
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Accès ouvert
2024
article
OpenAlex
Nana Nakahata, Mahiro Asano, Norikazu Abe, Haruka Ejiri et autres
The main cause of diffuse thyroid goiter is autoimmune chronic thyroiditis, otherwise known as Hashimoto's thyroiditis. Thyroid hormones play pivotal roles in growth and development during childhood. However, the prevalence of diffuse goiter and the relationships between diffuse goiter, thyroid volume, cysts …
jp
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Accès ouvert
2024
article
OpenAlex
Rina Tazaki, Yurie Kobashi, Nana Nakahata, Mahiro Asano et autres
There have been no systematic epidemiological evaluations of the relationship between thyroid autoimmunity and the clinical background of young patients with thyroid nodules. We aimed to clarify the clinical features associated with thyroglobulin or thyroperoxidase antibodies (thyroid autoantibodies [Tabs]) in children and …
jp
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Accès ouvert
2023
article
OpenAlex
Mizuki Sekino, Manabu Iwadate, Yukie Yamaya, Yoshiko Matsumoto et autres
In thyroid cancer, it has been suggested that PD-L1 overexpression is associated with some clinicopathological factors and prognosis. The aim of this study is to characterize the expression of PD-L1, the presence of the BRAFV600E mutation, as well as cellular and humoral …
jp
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Accès ouvert
2023
article
OpenAlex
Hiroki Shimura, Susumu Yokoya, Satoru Suzuki, Manabu Iwadate et autres
In response to concerns about health due to radiation exposure, the Fukushima Prefecture launched the Thyroid Ultrasound Examination program for residents aged 0-18 years at the time of the earthquake. Herein, we considered the confounding factors involved in the regional differences in …
jp
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Accès ouvert
2023
preprint
OpenAlex
Akira Sakai, Naohiro Tsuyama, Tetsuya Ohira, Misaki Sugai-Takahashi et autres
Abstract To investigate the effects of radiation exposure due to the Fukushima nuclear power plant accident, following the disaster Fukushima Prefecture launched thyroid ultrasound examinations of residents who were generally younger than 18 years at the time of the earthquake. As the …
jp
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Accès ouvert
2022
article
OpenAlex
Hiroki Shimura, Satoru Suzuki, Susumu Yokoya, Manabu Iwadate et autres
The Great East Japan Earthquake on March 11, 2011, and the subsequent tsunami caused an accident at the Fukushima Daiichi Nuclear Power Plant, in which extensive damage to the nuclear power reactors resulted in massive radioactive contamination. Fukushima Prefecture implemented the Thyroid …
jp
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Accès ouvert
2022
article
OpenAlex
Tomoki Nakaya, Kunihiko Takahashi, Hideto Takahashi, Seiji Yasumura et autres
BACKGROUND: After the first-round (Preliminary Baseline Survey) ultrasound-based examination for thyroid cancer in response to the accident at the Fukushima Daiichi Nuclear Power Plant in 2011, two rounds of surveys (Full-scale Survey) have been carried out in Fukushima Prefecture. Using the data …
jp
(code pays fourni par la source)