Eibert R. Heerdink

Glucocorticoid exposure and initiation of SSRIs among patients with rheumatoid arthritis: A nested case–control study in UK primary care

Elise J. Heesbeen, Patrick Cyriel Souverein, Eibert R. Heerdink, Elisabeth Yvonne Bijlsma et autres

AIM: The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case-control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety). …

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Conducting Medication Reviews: A Comparative Study Between ChatGPT ‐4 and Healthcare Professionals

Simone M K Ten Hoope, Sabrina Marongiu, Carl E. Siegert, Eibert R. Heerdink et autres

BACKGROUND: The increasing prevalence of patients with hyperpolypharmacy (> 10 medications) has made medication reviews increasingly complex. ChatGPT-4-Turbo (ChatGPT), a large language model, has demonstrated potential in healthcare applications and could potentially support medication reviews. OBJECTIVES: This study aimed to evaluate the …

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Early Identification of Cardiovascular Adverse Events Associated With Rofecoxib Using Real‐World Data From the UK : A Nested Case–Control and Case‐Crossover Study

Donya Moslemzadeh, Patrick Cyriel Souverein, Svetlana V. Belitser, Eibert R. Heerdink et autres

BACKGROUND: Traditional pharmacovigilance systems have limitations in detecting common adverse drug reactions. We investigated whether real-world data (RWD) could have detected rofecoxib's cardiovascular adverse effects earlier using nested case-control (NCC) and case-crossover (CCO) designs. METHODS: We included adult rofecoxib users from the …

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Patient Preferences and Attitudes Regarding the Environmental Impact of Medicines: A Discrete Choice Experiment

Milad Sadreghaemy, Daphne Philbert, Eibert R. Heerdink, Marcel L. Bouvy et autres

Background The healthcare sector contributes ~5% of global greenhouse gas emissions, with medicines responsible for ~10% throughout their lifecycle. Understanding how the environmental impact of medicines influences patients’ preferences relative to ease of use and cost supports interventions promoting appropriate medicine consumption, …

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‘De publieke markt’: Een kwaliteitsanalyse van de bedrijfsprocessen voor de invoering van ISO 9001:2008 m.b.t. (Europese) aanbestedingen.

Eibert R. Heerdink

Van Keulen Interieurbouw B.V. (VKI) is een bedrijf dat met verschillende bedrijven en handelsnamen opereert in zowel de private als publieke markt. De private markt bestaat uit nationale en internationale klanten op het gebied van interieurbouw. Op deze markt heeft het bedrijf …

Lithium: farmacologie in de psychiatrie

Ingeborg Wilting, Eibert R. Heerdink, Willem A. Nolen, Toine C. G. Egberts

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