Daniela Adolf

Rapid improvement of disease impact in patients with rheumatoid arthritis treated with upadacitinib: Results from a prospective real-world study

Torsten Witte, Uta Kiltz, E. Riechers, Daniela Adolf et autres

Introduction: The SELECT clinical trial program demonstrated upadacitinib to be an effective treatment for RA with an acceptable safety profile [ref:1], [ref:2], [ref:3], [ref:4], [ref:5], [ref:6]. Methods: UPwArds was a post-marketing observational [for full text, please go to the a.m. URL]

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Investigating video consultations as a new form of care for neuropalliative patients in specialized outpatient care: results from the project TANNE (telemedical answers to neurological inquires in real time)

Christiane Weck, Stefan Lorenzl, Kirsten Brukamp, Viacheslav Galchenko et autres

Background: Currently, there is no standardized care for neuropalliative outpatients in Germany. Those who require specialized palliative care often receive it from a Specialized Outpatient Palliative Care (SOPC) team or hospice, but without regularly access to neurological expertise. The TANNE project elaborated …

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Long-term outcomes of Lichtenstein and laparoscopic primary unilateral inguinal hernia repair: registry-based propensity score-matched analysis

Hendrik Christian Albrecht, Mateusz Trawa, Lennart Zimniak, Daniela Adolf et autres

BACKGROUND: Laparoscopic (transabdominal preperitoneal (TAPP) and totally extraperitoneal (TEP)) and Lichtenstein procedures are the most commonly used approaches for primary unilateral inguinal hernia repair. However, only limited long-term data are available to compare the outcomes of these techniques, particularly from large cohorts. …

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What is the relationship between hospital caseload and outcome in incisional hernia repair?—A registry-based analysis of 55,584 patients

F. Köckerling, R. Schwáb, K. Zarras, Bernhard J. Lammers et autres

INTRODUCTION: There is an ongoing controversal debate about whether the hospital volume (hospital case load) or the surgeon volume has a greater influence on outcome. The implications of high surgeon volume for the outcome have been demonstrated for ventral and incisional hernia …

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Inguinal Hernia Repair Using Absorbable Biosynthetic Mesh Versus Permanent Polypropylene Mesh: A Preliminary Comparative Study of 1-Year Outcomes

Ferdinand Köckerling, Kasia Bradbury, Daniela Adolf, Amit Badhwar

Introduction: Inguinal hernia repair with synthetic mesh became a gold standard due to durability and low recurrence rates. With the growing popularity of absorbable meshes in abdominal wall repairs, we evaluated performance of absorbable biosynthetic mesh and permanent synthetic mesh in inguinal …

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Comparison of short- and long-term outcomes using heavy- (3DMax™ Mesh) and lightweight (3DMax™ Light Mesh) mesh in inguinal hernia repair

Ferdinand Köckerling, Sarah Williams, Hartwig Riediger, Amit Badhwar et autres

Summary Purpose Inguinal hernia repair is one of the most common surgeries worldwide, with synthetic mesh as the standard of care. With interest in the potential of mesh weight to impact long-term outcomes, we compared short- and long-term safety and effectiveness outcomes …

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ABS0365 GLUCOCORTICOID-SPARING EFFECT OF UPADACITINIB IN PATIENTS WITH RHEUMATOID ARTHRITIS; POST-HOC ANALYSIS FROM THE NON-INTERVENTIONAL STUDY UPWARDS

Torsten Witte, Uta Kiltz, E. Riechers, Daniela Adolf et autres

Background: In clinical practice, continuous use of glucocorticoids (GCs) is common in patients with rheumatoid arthritis (RA) [1, 2]. According to EULAR guidelines, GCs are only recommended for short-term use during treatment initiation with conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs) and should …

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POS0894 HOW EFFECTIVE RIGHT FROM THE START A REAL-WORLD EVALUATION OF THE EFFECTIVENESS OF UPADACITINIB IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS WITHIN 12 WEEKS AFTER TREATMENT INITIATION

Uta Kiltz, S.M. Weiner, Bjoern Buehring, Philipp Klemm et autres

Background: Achieving low disease activity is a primary target when treating patients with axial spondyloarthritis (axSpA). The SELECT-AXIS clinical trials investigated the effectiveness and safety of Upadacitinib (UPA), a selective Janus kinase inhibitor, in axSpA patients treated in clinical practice [1–3]. The …

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Is the annual hospital volume associated with recurrence and chronic postoperative inguinal pain (CPIP) syndrome after inguinal hernia repair in laparo-endoscopic or open mesh technique (Lichtenstein)?

R. Bittner, Solveig Unger, Ferdinand Köckerling, Daniela Adolf

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AB0510 UNVEILING THE REAL-WORLD IMPACT OF UPADACITINIB – DOES CLINICAL REMISSION MIRROR THE PATIENT’S PERSPECTIVE ON RHEUMATOID ARTHRITIS?

Torsten Witte, Uta Kiltz, Florian Haas, E. Riechers et autres

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Predictors for severe persisting pain in rheumatoid arthritis are associated with pain origin and appraisal of pain

Christoph Baerwald, Edgar Stemmler, Sixten Gnüchtel, Katharina Jeromin et autres

OBJECTIVES: To determine the proportion of patients with rheumatoid arthritis (RA) with severe persisting pain and to identify predictive factors despite treatment-controlled disease activity. METHODS: This prospective multicentre study included outpatients with RA scheduled for escalation of anti-inflammatory treatment due to active …

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Is mesh pore size in polypropylene meshes associated with the outcome in Lichtenstein inguinal hernia repair: a registry-based analysis of 22,141 patients

Hendrik Christian Albrecht, Mateusz Trawa, F. Köckerling, Daniela Adolf et autres

INTRODUCTION: Experimental data show that large-pored meshes reduce foreign body reaction, inflammation and scar bridging and thus improve mesh integration. However, clinical data on the effect of mesh porosity on the outcome of hernioplasty are limited. This study investigated the relation of …

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