Denis S. Yunevich

Systemic Thrombolytic Therapy for Ischemic Stroke: Experience of the Regional Vascular Center

Oleg Mikhailovich Uryasev, A. V. Solovieva, Sergey B. Aksentyev, Denis S. Yunevich et autres

INTRODUCTION: Systemic thrombolysis is an effective and safe method of reperfusion therapy in ischemic stroke. However, the effectiveness and safety of different thrombolytic drugs are not the same. It is relevant to analyze the use of systemic thrombolytics in real clinical practice …

ru (code pays fourni par la source)

Advanced results of Fortelyzin® use in the FRIDOM1 study and real clinical practice

В. А. Марков, Dmitry Viktorovich Duplyakov, S. L. Konstantinov, Gernot Klein et autres

Aim.To study the effectiveness of Fortelyzin® in subgroups with different body weights in patients with ST-segment elevation acute myocardial infarction (STEMI) in the FRIDOM1 study and real clinical practice. Material and methods.Fortelyzin® was administered in a single-bolus dose of 15 mg over …

ru, gb, us, kr (code pays fourni par la source)

Nonimmunogenic staphylokinase in the treatment of acute ischemic stroke (FRIDA trial results)

Evgeny I. Gusev, M. Yu. Martynov, Nikolay A Shamalov, Elena Borisovna Yarovaya et autres

ЦЕЛЬ ИССЛЕДОВАНИЯ Изучение эффективности и безопасности неиммуногенной стафилокиназы (НС) в сравнении с алтеплазой (А) у пациентов с ишемическим инсультом (ИИ) в первые 4,5 ч от развития симптомов. МАТЕРИАЛ И МЕТОДЫ В открытом рандомизированном сравнительном исследовании «не меньшей эффективности» в параллельных группах НС …

ru, us (code pays fourni par la source)

Non-immunogenic recombinant staphylokinase versus alteplase for patients with acute ischaemic stroke 4·5 h after symptom onset in Russia (FRIDA): a randomised, open label, multicentre, parallel-group, non-inferiority trial

Eugene I. Gusev, M. Yu. Martynov, Alexey A Nikonov, Nikolay A Shamalov et autres

ru (code pays fourni par la source)

Efficiency and safety of various dual antiplatelet therapy strategies in patients undergoing percutaneous coronary intervention due to myocardial infarction

S. B. Aksentiev, A. V. Solovieva, Denis S. Yunevich

Aim. To compare the efficacy and safety of prasugrel, ticagrelor, or clopidogrel as part of dual antiplatelet therapy (DAPT) in patients undergoing percutaneous coronary intervention (PCI) due to myocardial infarction (MI). Material and methods. The observational study included 74 patients who underwent …

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Fortelyzin® in comparison with Metalyse® for ST-elevated myocardial infarction: one-year results and clinical outcomes of a multicenter randomized study FRIDOM1

В. А. Марков, Dmitry Viktorovich Duplyakov, S. L. Konstantinov, Gernot Klein et autres

Aim. Evaluate the one­year results and clinical outcomes of a multi­center randomized clinical trial FRIDOM1. Material and methods. The study FRIDOM1 was conducted in 11 clinical centers of the Russian Federation in the period 2014­2016. The study included 382 patients with acute …

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TO THE QUESTION OF EFFICACY AND SAFETY OF FORTELYZIN® THERAPY ON ACUTE CORONARY SYNDROME: TWO CLINICAL CASES

Denis S. Yunevich, S. B. Aksentiev

The article presents two clinical cases of successful reuse thrombolytic drug Fortelyzin® in the total dose of 25-30 mg observed by the authors in patients with acute coronary syndrome with ST-segment elevation, treated in the urgent cardiology department of the State budget …

The efficacy and safety of various schemes of systemic drug thrombolysis in myocardial infarction with ST-segment elevation in senile patients

Denis S. Yunevich

The results present the comparative analysis of the efficacy and safety of thrombolytic therapy with different drugs in 98 patients 75 years and older with myocardial infarction with ST-segment elevation. The prevalence of 28-day mortality was observed after the introduction of streptokinase …

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Comparative prognosis in eldery and senile patients with Q-myocardial infarction during 12 months of observation depending on different schemes of reperfusion therapy

Samar Bellil, S. S. Yаkushin, С Б Аксентьев, Denis S. Yunevich

In this article we studied the prognosis of various schemes of reperfusion therapy and subsequent medical treatment during a year of observation in elderly and senile patients with ST elevation myocardial infarction. We examined 80 patients, 46 of them were elderly, and …

ANALYSIS OF THE EFFICACY AND SAFETY OF THROMBOLYTIC THERAPY OF ACTILYSE IN PATIENTS ELDERLY AND SENILE AGE WITH MYOCARDIAL INFARCTION WITH ST-SEGMENT ELEVATION

Denis S. Yunevich, S. B. Aksentiev, Л В Денискина, О В Фокина et autres

The results present the research of parameters of the efficacy and safety of thrombolytic therapy (TLT) actilyse in 95 patients with myocardial infarction, depending on age. Observed increase in 28-day mortality and incidence of undesirable effects in individuals TLT older age groups. …