Charlotte Sophie Hansen

Sex shapes CD64 expression and vaccine-induced monocytic responses

Charlotte Sophie Hansen, Julie Sellau, Anastasia Langanz, Leonie Marie Weskamm et autres

Sex-specific differences influence vaccine-induced immunity, with females generally mounting more robust immune responses than males. While enhanced antibody production in females is well established, the cellular mechanisms underlying these differences remain elusive. Monocytes and monocyte-derived dendritic cells contribute to vaccine-induced immunity by …

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Additional file 1 of Sex shapes CD64 expression and vaccine-induced monocytic responses

Charlotte Sophie Hansen, Julie Sellau, Anastasia Langanz, Leonie Marie Weskamm et autres

Supplementary Material 1

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Sex shapes CD64 expression and vaccine-induced monocytic responses

Charlotte Sophie Hansen, Julie Sellau, Anastasia Langanz, Leonie Marie Weskamm et autres

Abstract Sex-specific differences influence vaccine-induced immunity, with females generally mounting more robust immune responses than males. While enhanced antibody production in females is well established, the cellular mechanisms underlying these differences remain elusive. Monocytes and monocyte-derived dendritic cells contribute to vaccine-induced immunity …

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Additional file 1 of Sex shapes CD64 expression and vaccine-induced monocytic responses

Charlotte Sophie Hansen, Julie Sellau, Anastasia Langanz, Leonie Marie Weskamm et autres

Supplementary Material 1

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Sex shapes CD64 expression and vaccine-induced monocytic responses

Charlotte Sophie Hansen, Julie Sellau, Anastasia Langanz, Leonie Marie Weskamm et autres

Abstract Sex-specific differences influence vaccine-induced immunity, with females generally mounting more robust immune responses than males. While enhanced antibody production in females is well established, the cellular mechanisms underlying these differences remain elusive. Monocytes and monocyte-derived dendritic cells contribute to vaccine-induced immunity …

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Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

Barbara Honecker, Charlotte Sophie Hansen, Hanna Lotter

Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender-specific behaviors that influence exposure risk and health-seeking practices, especially in low- and middle-income countries. Increasing evidence also highlights that biological …

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Sex shapes CD64 expression and vaccine-induced monocytic responses

Charlotte Sophie Hansen, Julie Sellau, Anastasia Langanz, Leonie Marie Weskamm et autres

Sex-specific differences influence vaccine-induced immunity, with females generally mounting more robust immune responses than males. While enhanced antibody production in females is well established, the cellular mechanisms underlying these differences remain elusive. Monocytes and monocyte-derived dendritic cells contribute to vaccine-induced immunity by …

Sex shapes CD64 expression and vaccine-induced monocytic responses

Charlotte Sophie Hansen, Julie Sellau, Anastasia Langanz, Leonie Marie Weskamm et autres

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Sex shapes CD64 expression and vaccine-induced monocytic responses

Charlotte Sophie Hansen, Julie Sellau, Matthias Knödler, Henrik Nausch et autres

Hansen, Charlotte Sophie; Sellau, Julie; Langanz, Anastasia; Weskamm, Leonie Marie; Wichern, Nele; Bea, Annika; Brandi, Johannes; Fehling, Helena; Groth, Nils; Lütkemeyer, Melanie; Knödler, Matthias; Nausch, Henrik; Stivachti, Eirini; Honecker, Barbara; Lotter, Hanna

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Transcriptome profiling of L. infantum-infected human macrophages reveals sex-specific type I interferon induction

Annika Bea, Helena Fehling, Fabian Hausmann, Melanie Lütkemeyer et autres

Sex-based differences in the immune system influence the clinical course of infectious diseases, including many parasitic infections. Field studies of human infections and controlled experimental rodent models have shown that certain clinical forms of leishmaniasis occur more frequently in males. Leishmania parasites …

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Entamoeba histolytica extracellular vesicles drive pro-inflammatory monocyte signaling

Barbara Honecker, Valentin A. Bärreiter, Katharina Höhn, Balázs Horváth et autres

The parasitic protozoan Entamoeba histolytica secretes extracellular vesicles (EVs), but so far little is known about their function in the interaction with the host immune system. Infection with E. histolytica trophozoites can lead to formation of amebic liver abscesses (ALAs), in which …

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Entamoeba histolytica extracellular vesicles drive pro-inflammatory monocyte signaling

Barbara Honecker, Valentin A. Bärreiter, Katharina Höhn, Balázs Horváth et autres

Abstract The parasitic protozoan Entamoeba histolytica secretes extracellular vesicles (EVs), but so far little is known about their function in the interaction with the host immune system. Infection with E. histolytica trophozoites can lead to formation of amebic liver abscesses (ALAs), in …

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