Accès ouvert
2025
article
OpenAlex
Djivan Prentout, Daria Bykova, Carla Hoge, Daniel M. Hooper et autres
Most of our understanding of the fundamental processes of mutation and recombination stems from a handful of disparate model organisms and pedigree studies of mammals, with little known about other vertebrates. To gain a broader comparative perspective, we focused on the zebra …
us, au
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Djivan Prentout, Daria Bykova, Carla Hoge, Daniel M. Hooper et autres
Abstract Most of our understanding of the fundamental processes of mutation and recombination stems from a handful of disparate model organisms and pedigree studies of mammals, with little known about other vertebrates. To gain a broader comparative perspective, we focused on the …
us, au
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Carla Hoge, Marc de Manuel, Mohamed Mahgoub, Naima Okami et autres
In some mammals, notably humans, recombination occurs almost exclusively where the protein PRDM9 binds, whereas in vertebrates lacking an intact PRDM9 , such as birds and canids, recombination rates are elevated near promoter-like features. To determine whether PRDM9 directs recombination in nonmammalian …
us, ch
(code pays fourni par la source)
Accès ouvert
2023
dataset
OpenAlex
Marc de Manuel, Carla Hoge
us
(code pays fourni par la source)
Accès ouvert
2023
dataset
OpenAlex
Marc de Manuel, Carla Hoge
us
(code pays fourni par la source)
Accès ouvert
2023
dataset
OpenAlex
Marc de Manuel, Carla Hoge
us
(code pays fourni par la source)
Accès ouvert
2023
preprint
OpenAlex
Carla Hoge, Marc de Manuel, Mohamed Mahgoub, Naima Okami et autres
Abstract In vertebrates, there are two known mechanisms by which meiotic recombination is directed to the genome: in humans, mice, and other mammals, recombination occurs almost exclusively where the protein PRDM9 binds, while in species lacking an intact PRDM9 , such as …
us, ch
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Young Mi Kwon, Nathan Vranken, Carla Hoge, Madison R Lichak et autres
Siamese fighting (betta) fish are among the most popular and morphologically diverse pet fish, but the genetic bases of their domestication and phenotypic diversification are largely unknown. We assembled de novo the genome of a wild Betta splendens and whole-genome sequenced 98 …
us, be, gb, sg, ch, fr, nl
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Maria Izabel A. Cavassim, Zachary Baker, Carla Hoge, Mikkel Heide Schierup et autres
In most mammals and likely throughout vertebrates, the gene PRDM9 specifies the locations of meiotic double strand breaks; in mice and humans at least, it also aids in their repair. For both roles, many of the molecular partners remain unknown. Here, we …
dk, us
(code pays fourni par la source)
Accès ouvert
2021
preprint
OpenAlex
Young Mi Kwon, Nathan Vranken, Carla Hoge, Madison R Lichak et autres
Abstract Siamese fighting fish, commonly known as betta, are among the world’s most popular and morphologically diverse pet fish, but the genetic processes leading to their domestication and phenotypic diversification are largely unknown. We assembled de novo the genome of a wild …
us, de, be, gb, sg, ch, fr, nl
(code pays fourni par la source)
2020
conference-abstract
OpenAlex
Jihong Xu, E. Geng, L A Brake, JA Mellia et autres
us
(code pays fourni par la source)
Accès ouvert
2019
article
OpenAlex
V. Talya Yerlici, Michael W Lu, Carla Hoge, Richard V. Miller et autres
Extrachromosomal circular DNA (eccDNA) is both a driver of eukaryotic genome instability and a product of programmed genome rearrangements, but its extent had not been surveyed in Oxytricha, a ciliate with elaborate DNA elimination and translocation during development. Here, we captured rearrangement-specific …
us
(code pays fourni par la source)