Hyun Soo Park

Dynamic Changes in Midbrain–Striatal Association and Their Relationship With Levodopa‐Induced Dyskinesia in Parkinson’s Disease

Eun Hye Jeong, Jae Yong Lee, Hyun Soo Park, Yoo Sung Song

Background The neurobiological pathology of levodopa‐induced dyskinesia (LID) remains unclear despite its prevalence. Emerging evidence suggests a critical interplay between dopaminergic and serotonergic systems in the development of LID. Objective This study aimed to investigate longitudinal changes in striatal and midbrain SBRs …

kr, Éthiopie, pr (code pays fourni par la source)

Fetal malformations in women with pregestational diabetes mellitus based on pre-pregnancy fasting plasma glucose levels

Subeen Hong, Kyung A. Lee, Young Mi Jung, Ji‐Hee Sung et autres

To evaluate the risk of fetal malformation in pregnant women with pregestational diabetes mellitus based on pre-pregnancy fasting plasma glucose (FPG) levels. This cohort study used the Korean Health Insurance Review and Assessment (HIRA) database, including 5,687 women with pre-pregnancy diabetes and …

us, gb, kr, jp (code pays fourni par la source)

Antenatal Corticosteroid in Twin-Pregnant Women at Risk of Late Preterm Delivery

Seung Mi Lee, Hyun Soo Park, Soo Ran Choi, Hyeon Ji Kim et autres

Importance: Recent guidelines have recommended corticosteroid injection in women with singleton pregnancies at risk of late preterm delivery. However, the effectiveness of antenatal corticosteroid administration in women with twin pregnancies at risk of late preterm delivery has not been evaluated, and studies …

kr, us (code pays fourni par la source)

Glycosylated Hemoglobin Levels in the Third Trimester for Predicting Adverse Pregnancy and Neonatal Outcomes in Women with Pre-Gestational Diabetes: A Multi-Center Retrospective Cohort Study in South Korea

Suyeon Park, Mi-Ju Kim, Subeen Hong, Ji‐Hee Sung et autres

Background/Objectives: The objective of this study is to investigate pregnancy and neonatal outcomes in women with pre-gestational diabetes (PGDM) in the Korean population and compare outcomes according to glycosylated hemoglobin (HbA1c) levels in the third trimester. Methods: Singleton pregnant women with PGDM, …

kr, jp, us (code pays fourni par la source)

Diagnostic Efficacy of Cervical Elastography in Predicting Spontaneous Preterm Birth in Pregnancies with Threatened Preterm Labor

Hayan Kwon, Ji‐Hee Sung, Hyun Soo Park, Ja‐Young Kwon et autres

Background/Objective: Accurately identifying women at high risk for preterm birth among those with threatened preterm labor (PTL) is crucial for effective interventions or tocolytic management to reduce preterm birth and its complications. This study aimed to determine the predictive value of cervical …

us, kr, jp (code pays fourni par la source)

Maternal and Neonatal Outcomes Based on Changes in Glycosylated Hemoglobin Levels During First and Second Trimesters of Pregnancy in Women with Pregestational Diabetes: Multicenter, Retrospective Cohort Study in South Korea

Mi Ju Kim, Suyeon Park, Sooran Choi, Subeen Hong et autres

This study compared glycosylated hemoglobin (HbA1c) levels in the first and second trimesters of pregnancy and assessed maternal and neonatal outcomes according to HbA1c variations among women with pregestational diabetes. This retrospective, multicenter Korean study involved mothers with diabetes who had given …

kr, us (code pays fourni par la source)

206 Fetal malformations in women with overt diabetes mellitus based on pre-pregnancy fasting blood sugar levels

Subeen Hong, Kyung A. Lee, Young Mi Jung, Won Young Wi et autres

kr, Éthiopie, pr (code pays fourni par la source)

Impacts of Tocolytics on Maternal and Neonatal Glucose Levels in Women With Gestational Diabetes Mellitus

Subeen Hong, Hyun‐Joo Seol, JoonHo Lee, Han Sung Hwang et autres

BACKGROUND: We investigated the impacts of tocolytic agents on maternal and neonatal blood glucose levels in women with gestational diabetes mellitus (GDM) who used tocolytics for preterm labor. METHODS: This multi-center, retrospective cohort study included women with GDM who were admitted for …

kr, us (code pays fourni par la source)

Radiosynthesis and whole‐body distribution in mice of a 18F‐labeled azepino[4,3‐b]indole‐1‐one derivative with multimodal activity for the treatment of Alzheimer's disease

Sang‐Hee Lee, Rosa Purgatorio, Francesco Samarelli, Marco Catto et autres

Abstract Recently, the azepino[4,3‐b]indole‐1‐one derivative 1 showed in vitro nanomolar inhibition against butyrylcholinesterase (BChE), the ChE isoform that plays a role in the progression and pathophysiology of Alzheimer's disease (AD), and protects against N‐methyl‐ d‐aspartate‐induced neuronal toxicity. Three 9‐R‐substituted (R = F, …

kr, it (code pays fourni par la source)

MRI-based breast cancer radiogenomics using RNA profiling: association with subtypes in a single-center prospective study

Ah Young Park, Mi-Ryung Han, Bo Kyoung Seo, Hye-Yeon Ju et autres

BACKGROUND: There are few prospective studies on the correlations between MRI features and whole RNA-sequencing data in breast cancer according to molecular subtypes. The purpose of our study was to explore the association between genetic profiles and MRI phenotypes of breast cancer …

kr, jp (code pays fourni par la source)

Theranostic Surrogacy of [123I]NaI for Differentiated Thyroid Cancer Radionuclide Therapy

Su Bin Kim, Min Seob Lee, In Ho Song, Hyun Soo Park et autres

Precise dosimetry has gained interest for interpreting the response assessments of novel therapeutic radiopharmaceuticals, as well as for improving conventional radiotherapies such as the “one dose fits all” approach. Although radioiodine as same-element isotope theranostic pairs has been used for differentiated thyroid …

kr (code pays fourni par la source)

A Spatial Transcriptomics based Label-Free Method for Assessment of Human Stem Cell Distribution and Effects in a Mouse Model of Lung Fibrosis

Jeongbin Park, Dongjoo Lee, Jae Eun Lee, Daeseung Lee et autres

Abstract Recently, cell therapy has emerged as a promising treatment option for various disorders. Given the intricate mechanisms of action (MOA) and heterogenous distribution in target tissues inherent to cell therapy, it is necessary to develop more sophisticated, unbiased approaches to evaluate …

kr (code pays fourni par la source)