2026
article
OpenAlex
Kexun Kenneth Chen, Tina Hardin, Ali Mohtasham, Joseph F Orlando et autres
INTRODUCTION: Low back pain (LBP) is a leading cause of disability and a common reason for emergency department (ED) presentation. Although clinical guidelines recommend community-based treatment for non-specific LBP, a range of factors drive people to seek hospital-based care in Australia. This …
au
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Accès ouvert
2025
review
OpenAlex
Kexun Kenneth Chen, Paul Edward Rolan, Mark Rowland Hutchinson, Rutger M. J. de Zoete
ABSTRACT Background Temporal summation of pain (TSP) is a dynamic quantitative sensory test reflecting pain facilitation. Variability in TSP paradigms challenges cross‐study comparisons and raises concerns about reliability. This systematic review and meta‐analysis evaluated the reliability of TSP in healthy and clinical …
au
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Accès ouvert
2025
article
OpenAlex
Xiaorui Ruan, Kexun Kenneth Chen, Ziye Li, Jianhui Wei et autres
BACKGROUND: To explore maternal pregestational and periconceptional factors associated with low birth weight in offspring and inform the development of targeted interventions. METHODS: A prospective birth cohort involving 34,104 pregnant women and their offspring was constructed. The participants were enrolled during 8-14 …
cn
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Accès ouvert
2025
article
OpenAlex
Hanjun Liu, Kexun Kenneth Chen, Tingting Wang, Xiaorui Ruan et autres
BACKGROUND: Previous studies predominantly focused on single types of congenital birth defects (CBDs) or specific national prevalence. This study adopts a holistic perspective to assess current trends and health inequalities in birth incidence rate of various types of CBDs, providing novel insights …
cn
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Accès ouvert
2025
review
OpenAlex
Iresha Dilhari Senarath, Ishanka Weerasekara, Melissa Humphries, Kexun Kenneth Chen et autres
BACKGROUND: Every 7 out of 10 people will experience neck pain at some point during their lifetime. A large proportion of these cases will develop into recurrent or chronic conditions. Typically, physical exercise for neck pain seems to be modestly beneficial, but …
lk, au
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Accès ouvert
2024
review
OpenAlex
Kexun Kenneth Chen, Paul Edward Rolan, Mark Rowland Hutchinson, Cameron Dickson et autres
BACKGROUND AND OBJECTIVE: Temporal summation of pain (TSP) and conditioned pain modulation (CPM) are the two most commonly used clinical measures of central sensitization (CS). However, the effectiveness of exercise on TSP and CPM has yet to be evaluated. This review aims …
au
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Accès ouvert
2024
article
OpenAlex
Juan Zou, Yaokun Chen, Zeqi Ji, Danyi Liu et autres
Background: is regarded as a new biomarker for cancer, especially for non-small cell lung cancer and ovarian cancer. However, its role in breast cancer (BC) has not yet been determined. Methods: In this research, we used a bioinformatics approach to assess the …
cn
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Accès ouvert
2023
review
OpenAlex
Cameron Dickson, Rutger M. J. de Zoete, Carolyn F. Berryman, Philip M. Weinstein et autres
OBJECTIVE: To identify and synthesize patient-related barriers to and enablers of the implementation of high-value physiotherapy (HVP) for chronic pain. Furthermore, to review what patient-related interventions have been used to facilitate the implementation of HVP for chronic pain, as well as their …
au
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Accès ouvert
2023
article
OpenAlex
Kexun Kenneth Chen, Mark Rowland Hutchinson, Paul Edward Rolan, Rutger M. J. de Zoete
Exercise-induced hypoalgesia (EIH) has been found to vary widely within individuals with chronic neck pain (NP). Research has suggested that the presence of central sensitization within a subgroup of individuals with chronic NP might be a mediating factor to explain the relationship …
au
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Accès ouvert
2022
article
OpenAlex
BaoLin Pauline Soh, Shuen Yee Lee, Wai Yin Wong, Benedict Wei Jun Pang et autres
OBJECTIVES: This study establishes age- and sex-specific reference values for fat mass index (FMI), lean mass index (LMI), appendicular LMI (aLMI), and body fat distribution indices including Android/Gynoid % fat ratio and Trunk/Limb % fat ratio in multi-ethnic Singaporean adults. METHODS: A …
sg
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2022
article
OpenAlex
Lay Khoon Lau, Khalid Bin Abdul Jabbar, Kexun Kenneth Chen, Wei Ting Seah et autres
INTRODUCTION: Gait variability is associated with frailty, dementia, and falls. Studies on the association of physiological and cognitive factors with gait variability have seldom included middle-aged adults, even though these adults already experienced loss of muscular strength and postural stability. This study …
sg, au
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Accès ouvert
2022
article
OpenAlex
Nien Xiang Tou, Shiou Liang Wee, Benedict Wei Jun Pang, Lay Khoon Lau et autres
Increase in body fat and reduced muscle mass are common body composition changes with age and precedes functional impairment. However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the …
sg
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