2025
article
OpenAlex
Henricco Zapparoli, Ana Carolina Pedrosa, Jorgea Pradieé, Guilherme Ferreira da Silva et autres
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Accès ouvert
2023
article
OpenAlex
Driele Neske Garcia, Jéssica D. Hense, Bianka M. Zanini, José V.V. Isola et autres
Cellular senescence is a defense mechanism to arrest proliferation of damaged cells. The number of senescent cells increases with age in different tissues and contributes to the development of age-related diseases. Old mice treated with senolytics drugs, dasatinib and quercetin (D+Q), have …
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2022
conference-paper
OpenAlex
Jorgea Pradieé, P. Quadros, K. Calderan, João Rocha et autres
Accès ouvert
2021
article
OpenAlex
Tatiana D. Saccon, Monique Tomazele Rovani, Driele Neske Garcia, Jorgea Pradieé et autres
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2020
article
OpenAlex
Bianka M. Zanini, Kelvin Ruan Da Silva Andrade, Jorgea Pradieé, Gabriel Barreto Veiga et autres
The aim of this study was to investigate the effect of calorie restriction (CR) during pregnancy in mice on metabolism and ovarian function in the offspring. Pregnant female mice were divided into two groups, a control group and a CR group (n=7 …
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Accès ouvert
2020
preprint
OpenAlex
Tatiana D. Saccon, Monique Tomazele Rovani, Driele Neske Garcia, Jorgea Pradieé et autres
Abstract Objective The aim of the study was to evaluate the role of growth hormone (GH) in DNA damage, macrophage infiltration and the granulosa cells number of primordial and primary follicles. Methods For these experiments six groups of female mice were used. …
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2019
article
OpenAlex
Renato Herdina Erdmann, Marcel Henrique Blank, Rodrigo Neca Ribeiro, Marcos José de Oliveira et autres
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Accès ouvert
2019
article
OpenAlex
Patrícia Carvalho Gindri, Natália Ávila de Castro, B. Mion, Bernardo Garziera Gasperin et autres
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Accès ouvert
2019
conference-abstract
OpenAlex
Driele Neske Garcia, Tatiana D. Saccon, Joao Alveiro Alvarado Rincón, Jorgea Pradieé et autres
Abstract The ovarian follicular reserve of primordial follicle declines with aging in female mammals. Caloric restriction (CR) has been shown to increase the preservation of the ovarian follicular reserve. Likewise, rapamycin has similar effects to CR on the ovarian reserve. Therefore, the …
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Accès ouvert
2019
article
OpenAlex
Joao Alveiro Alvarado Rincón, Patrícia Carvalho Gindri, B. Mion, Giuliana de Avila Ferronato et autres
The aim of this study was to evaluate the effect of exposing bovine oocytes to lipopolysaccharides (LPS) in vivo and in vitro on early embryo development. In experiment 1, cumulus oocyte complexes (COCs, n = 700/group) were challenged with 0, 0.1, 1.0 …
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2019
article
OpenAlex
Lucas Teixeira Hax, Joao Alveiro Alvarado Rincón, Augusto Schneider, L. M. C. Pegoraro et autres
Around 60-80% of oocytes maturated in vivo reached competence, while the proportion of maturation in vitro is rarely higher than 40%. In this sense, butafosfan has been used in vivo to improve metabolic condition of postpartum cows, and can represent an alternative …
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Accès ouvert
2019
article
OpenAlex
Driele Neske Garcia, Tatiana D. Saccon, Jorgea Pradieé, Joao Alveiro Alvarado Rincón et autres
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