Zhenqiang Wang

Spatially Decoupled Piezoelectric Hydrogel with Trauma-Driven Migration of Engineered Platelets for Divergent Mitochondrial Fate Programming in Postoperative Cancer Therapy

Lei Liu, Daqing Xia, Yang Yang, Lunli Xiang et autres

Abstract Postoperative recurrence and metastasis remain major obstacles in solid tumor therapy because surgical intervention creates a spatially conflicting microenvironment. Here, a spatially decoupled piezoelectric hydrogel (BP@Gel) was developed to enable spatially divergent mitochondrial fate programming across the tumor-surgical-margin interface. Engineered platelets …

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Flash annealing yields a 1.5 GPa low-carbon martensitic/bainitic steel with high ductility and toughness

Binbin Wu, Z. Q. Wang, Tianyu Zhou, Yuewu Li et autres

Low-carbon martensitic/bainitic (LCM/B) steels typically exhibit strengths below 1 GPa and are susceptible to tempering embrittlement. This work proposed a flash annealing (FA) process as an alternative to conventional tempering, which enabled the achievement of 1.5 GPa-grade Ni- and Al-alloyed LCM/B steels …

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Bioactive Multifunctional Hydrogel Scaffolds Remodel the Inflammatory Microenvironment and Osteogenic-Osteoclastic Homeostasis to Advance Osteoporotic Bone Defect Repair

Zhenqiang Wang, Changjiang Gu, Yifan Tang, Xin‐Jin Su et autres

Bone defect repair in patients with osteoporosis remains a major challenge due to the imbalance in bone metabolism and the inflammatory microenvironment with high levels of reactive oxygen species. To address these issues, a three-dimensional-printed bioactive multifunctional hydrogel scaffold consisting of a …

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Electropulsing-enhanced interfacial recrystallization in ultrasonic consolidation of Cu/Al heterogeneous lamellar structure

Yanyuan Zhou, Zhenqiang Wang, Su Zhao, Fengchun Jiang

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Insights into the anticorrosion mechanism of carbon quantum dots as green inhibitors for AZ31 Mg alloy in 3.5 wt% NaCl solution

Wenting Zhao, Rui Wan, Zhenqiang Wang, Zhili Gong et autres

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Exo- and endo-cavities modulated coordination cages for consecutive supramolecular catalysis

Chang Li, Tian‐Pu Sheng, Zhenqiang Wang, Feng‐Rong Dai

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TRIM25 ‐Mediated Ubiquitination and Degradation of SOX8 Promotes Ligament Fibroblast Osteogenic Differentiation and Regulates OPLL Progression by Inhibiting OSR2 Transcription

Zhenqiang Wang, Yifan Tang, Changjiang Gu, M. �ift�io lu et autres

Background: Ossification of the posterior longitudinal ligament (OPLL) is a pathological condition characterized by ectopic ossification of spinal ligaments, primarily driven by abnormal osteogenic differentiation of ligament fibroblasts with stem cell-like properties. The SOX transcription factor family is crucial in regulating cell …

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CREB binding protein (CREBBP): Structure-based perspectives for the development of clinical inhibitors

Rongxing Liu, Jiaxin Li, Qing Nian, Gao Tu et autres

Acetylation is an essential process in biological processes. In tissues, protein acetylation occurs mainly at lysine (K) residues. The balance between acetylation and deacetylation is under the control of two enzyme families, histone acetyltransferase (HAT) and histone deacetylase (HDAC), respectively. Although there …

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N, S‑carbon quantum dots as a green corrosion inhibitor for brine heaters in multistage flash desalination systems

Rui Wan, Wenting Zhao, Xiao Wei Sun, Zhenqiang Wang et autres

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Roxburgh pear leaf extract as a sustainable anti-corrosion effect for copper in 0.5 M H2SO4 solution

Xiao Wei Sun, Wenting Zhao, Rui Wan, Guohua Lu et autres

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Value of SOFA score, APACHE II score, and WBC count for mortality risk assessment in septic patients: A retrospective study

Dengkai Li, Yan-fang Wei, Chunfang Zhang, Yunsheng Yang et autres

Sepsis is characterized by rapid onset, swift progression, and poor prognosis. Delay in early recognition and treatment may easily escalate to septic shock, resulting in a markedly high mortality rate. Early prognosis assessment holds significant value in enhancing the clinical outcomes of …

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Dynamical versions of Morgan's Uncertainty Principle and Electromagnetic Schrödinger Evolutions

Shanlin Huang, Zhenqiang Wang

This paper investigates the unique continuation properties of solutions of the electromagnetic Schrödinger equation $$ i\partial_{t}u(x,t)+(\nabla-i A)^{2}u(x,t)=V(x,t)u(x,t)\,\,\,\, \mbox{in} \,\,\,\mathbb{R}^{n}\times [0,1], $$ where $A$ represents a time-independent magnetic vector potential and $V$ is a bounded, complex valued time-dependent potential. Given $10$ and there …