Kishore P. Bhusari

Development of a stability indicating HPTLC method for the estimation of olanzapine in pharmaceutical dosage forms

Reema Ahmed, Kishore P. Bhusari, Madhukar Tajne, Shah Alam Khan

in, om (code pays fourni par la source)

Synthesis and Antimycobacterial Activity of Some Heterocyclic Derivatives

Sandip Shrikishan Kshirsagar, Rajashree S. Chavan, Nikhil D. Amnerkar, Kishore P. Bhusari

in (code pays fourni par la source)

Stability Indicating High Performance Thin Layer Chromatographic Method for the Determination of Tramadol Hydrochloride in Pharmaceutical Formulation

Bhagyashree R. Dhumal, Kishore P. Bhusari, Arjun Patra, Suresh Thareja et autres

The proposed stability indicating method for the determination of tramadol hydrochloride by high-performance thin-layer chromatography in the pharmaceutical formulations was found to be specific, precise, and validated. The stationary phase employed was a precoated silica gel 60 F254 aluminum TLC plate. Several …

in (code pays fourni par la source)

Docking study of p-hydroxybenzohydrazide derivatives as tyrosine kinase inhibitors and anticancer agents

Prashant Patil, Nikhil D. Amnerkar, eep S. Pathare, Kishore P. Bhusari

Thiazole and thiazolidene derivatives of p-hydroxybenzohydrazide were found having anti cancer activity. These compounds were showed the inhibitory effect against various cancerous cell lines. An attempt was made to find the correlation in these anticancer agents as epidermal growth factor receptor (EGFR): …

Synthesis and biological evaluation of some 4-(6-substituted-1,3-benzothiazol-2-yl)amino-1,3-thiazole-2-amines and their Schiff bases

Nikhil D. Amnerkar, Bhoomendra A. Bhongade, Kishore P. Bhusari

With the aim of obtaining newer biologically active compounds, a series of 4-(6-substituted-1,3-benzothiazol-2-yl)amino-1,3-thiazole-2-amines (9–12) and 4-(6-substituted-1,3-benzothiazol-2-yl)amino-2-(4-substitutedphenyl-methylidene)amino-1,3-thiazole (13–28) were synthesized. The structures of all the synthesized compounds were confirmed by spectral (FTIR, 1H NMR and EI-MS) data and elemental (C, H, N) analysis. …

in, ae (code pays fourni par la source)

Pharmacological evaluation for anti-asthmatic and anti-inflammatory potential ofWoodfordia fruticosaflower extracts

Mahavir H. Ghante, Kishore P. Bhusari, N.J. Duragkar, Nitin B. Ghiware

CONTEXT: Woodfordia fruticosa Kurz. (Lythraceae) flowers are ethnopharmacologically acclaimed in the Indian medicinal system to treat asthma. OBJECTIVE: To evaluate W. fruticosa flower extracts for anti-asthmatic effect. MATERIALS AND METHODS: Ethyl acetate, acetone, methanol, and hydro-alcohol extracts of W. fruticosa flowers were …

in (code pays fourni par la source)

3D-QSAR study, synthesis and biological evaluation of p-hydroxy benzohydrazide derivatives as antimicrobial agents

Prashant Patil, Nikhil D. Amnerkar, eep S. Pathare, Kishore P. Bhusari

Series of compounds N’-[(3-Substituted alkyl/aryl)-4-(substituted aryl)-1,3-thiazol-2-ylidene]-4- hydroxybenzohydrazide (10-37) were designed via 3D-QSAR studies. These compounds were synthesized by reacting compounds (3-9) with various substituted phenacyl bromides in presence of sodium acetate. Good yield of compounds (10-37) were obtained by established reaction. Structure …

3D-QSAR Studies on Isocoumarin-based Urokinase-type Plasminogen Activator (uPA) Inhibitors Employing Linear and Non-linear Regression Analysis Methods

Bhoomendra A. Bhongade, Nikhil D. Amnerkar, Sirajunisa Talath, Kishore P. Bhusari et autres

Bronchorelaxant, mast cell stabilizing, anti-inflammatory and antioxidant activity of Randia dumetorum (Retz.) Lamk. extracts.

Mahavir H. Ghante, Kishore P. Bhusari, N.J. Duragkar, Nishant S. Jain et autres

Randia dumetorum (RD) fruits in different form have been ethnopharmacologically reported to possess antiasthmatic property. Therefore, present study was undertaken to evaluate two different extracts of RD i.e., ethyl acetate (RD-EA) and methanol (RD-ME) for bronchorelaxant, anti-inflammatory, mast cell stabilizing and antioxidant …

Synthesis of 5-Benzenesulphonamido-1, 3, 4-Thiadiazol 2-Sulphonamide Derivatives as an Antiepileptic Agent

Amol Warokar, Prasanna Deshpande, A. S. Mundhey, N.J. Duragkar et autres

Sulphonation of 5-amino-1, 3, 4-thiadiazol-2-[N-(substituted benzoyl)] sulphonamide (4a-c) with substituted phenylsulphonyl chloride (5a-d) was carried to synthesized 5-(substituted bezenesulphonamido)-1, 3, 4-thiadiazol-2[N-(substituted benzoyl)] sulphonamide (6a-m). As per Schotten-Boumann method, benzoylation of acetazolamide (1) and substituted benzoyl chloride (2a-c) was carried out in the …

Design and Synthesis of p-hydroxybenzohydrazide Derivatives for their Antimycobacterial Activity

Ritesh Bhole, Deepak.D. Borkar, Kishore P. Bhusari, Prashant Patil

The main mycobacterial infection in human is tuberculosis caused by Mycobacterium tuberculosis. Tuberculosis is the leading infectious cause of death in the world. Therefore there is continuing and compelling need for new and improved treatment for tuberculosis. The entire logic towards design …

it, in (code pays fourni par la source)

ChemInform Abstract: Synthesis, Antihypertensive Activity, and 3D‐QSAR Studies of Some New p‐Hydroxybenzohydrazide Derivatives.

Ritesh Bhole, Kishore P. Bhusari

Abstract A variety of new thiadiazole (V) and thiazole derivatives (IX) are synthesized starting from p‐hydroxybenzohydrazide (I).