Aimen Shafiq

POSTER: CT-705: Impact of Chronic Kidney Disease on Clinical Outcomes and Resource Utilization in Hematopoietic Stem Cell Transplantation: Insights From the Nationwide Readmissions Database

Abdullah Nawaz Rai, Mariam Shahabi, Muhammad Ibrahim Rashid, Eyman Wasim et autres

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CT-705: Impact of Chronic Kidney Disease on Clinical Outcomes and Resource Utilization in Hematopoietic Stem Cell Transplantation: Insights From the Nationwide Readmissions Database

Abdullah Nawaz Rai, Mariam Shahabi, Muhammad Ibrahim Rashid, Eyman Wasim et autres

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Trends in Cardiac Arrest Mortality Among Young Adults in the United States, 1999 to 2024

Aimen Shafiq, Mushood Ahmed, Eeshal Zulfiqar, Maryam Shahzad et autres

BACKGROUND: Cardiac arrest (CA) affecting young individuals has been identified as a public health concern in the United States. OBJECTIVES: This study analyzes mortality trends associated with CA in young adults in the United States, focusing on demographic and regional disparities. METHODS: …

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Targeting Aldosterone Biosynthesis in Uncontrolled and Resistant Hypertension: A Systematic Review and Meta-Analysis of Randomized Trials of Lorundrostat and Baxdrostat

Ravi Pandey, Muhammad Ahmad, Ali Rohan, Iqra Nurie et autres

Background Aldosterone excess contributes to uncontrolled and resistant hypertension, making aldosterone synthase inhibition a promising therapeutic strategy. Recent randomized trials have evaluated the selective aldosterone synthase inhibitors Lorundrostat and Baxdrostat; however, their efficacy and safety have not been comprehensively synthesized. Methods PubMed, …

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Patent foramen ovale: when does it need closure?

Aimen Shafiq, Richard A. Krasuski

A patent foramen ovale (PFO) is present in approximately 25% of the general population. Its clinical significance is primarily in patients with cryptogenic stroke. Randomized trials have evaluated whether transcatheter PFO closure reduces recurrent stroke compared to medical therapy. Evidence outside stroke, …

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26-A-19416-ACC MORTALITY TRENDS IN CARDIAC ARREST AMONG YOUNG AMERICANS FROM 1999-2023

Qutaiba Mohammad Ahmad Albustanji, Tharun Adithya Natesan, Gabriele Volucke, Mushood Ahmed et autres

Impact of influenza vaccination on in-hospital outcomes among patients with heart failure and acute respiratory illness

Aimen Shafiq, Syed Sarmad Javaid, Apurva Popat, Hamza Asif et autres

Influenza vaccination is recommended to patients with heart failure (HF), who are vulnerable to severe complications from respiratory infections. However, data on its impacts on in-hospital outcomes remain limited. We analyzed the National Inpatient Sample (2018 to 2020), including adults (≥ 18 …

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Metabolic dysfunction-associated steatotic liver disease and cardiovascular disease: a state-of-the-art review

Aimen Shafiq, Ahmed Mustafa Rashid, Syed Raza Shah, Nicholas WS Chew et autres

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly nonalcoholic fatty liver disease, is the most prevalent chronic liver disease worldwide, affecting more than 30% of adults and up to 70–90% of individuals with obesity or type 2 diabetes mellitus. Cardiovascular disease (CVD) represents …

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MASLD and cardiovascular disease: a state-of-the-art review

Aimen Shafiq, Ahmed Mustafa Rashid, Syed Raza Shah, Nicholas WS Chew et autres

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly nonalcoholic fatty liver disease, is the most prevalent chronic liver disease worldwide, affecting more than 30% of adults and up to 70–90% of individuals with obesity or type 2 diabetes mellitus. Cardiovascular disease (CVD) represents …

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The Overlooked Crisis: Drug Self-Intoxication Mortality Increased at 5 Times the Rate of Suicide Mortality During the US Opioid Epidemic (1999-2023)

Mushood Ahmed, Eeshal Zulfiqar, Aimen Shafiq, Maryam Shahzad et autres

OBJECTIVE: To examine demographic and regional variations in self-injury mortality (SIM) among individuals aged 15 years or older in the United States with mental and behavioral disorders as contributing causes of death from 1999 to 2023. METHODS: Death certificates from the CDC-WONDER …

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Aortic valve replacement in asymptomatic severe aortic stenosis. A focused review

Aimen Shafiq, Rohan Dev Trehan, Mitja J. Lainscak, Sanjeev Trehan

Asymptomatic severe aortic stenosis (AS) has traditionally been managed with watchful waiting because of low annual sudden death rates (<1%) and concerns regarding procedural risk. Emerging randomized data indicate that irreversible myocardial injury may occur before symptom onset and that early aortic …

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GLP‐1 and Dual GLP‐1/GIP Receptor Agonists in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Systematic Review and Meta‐Analysis

Mushood Ahmed, Aimen Shafiq, Tallal Mushtaq Hashmi, Raheel Ahmed et autres

This comprehensive meta-analysis reveals that GLP-1 and dual GLP-1/GIP receptor agonists are associated with reduced risk of composite cardiovascular endpoints and worsening heart failure events. However, no statistically significant differences were observed regarding all-cause or cardiovascular mortality.

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