Xu Chen

RecGPT-V2 Technical Report

Chao Yi, Dian Chen, Gaoyang Guo, Jian Wu et autres

Large language models (LLMs) have demonstrated remarkable potential in transforming recommender systems from implicit behavioral pattern matching to explicit intent reasoning. While RecGPT-V1 successfully pioneered this paradigm by integrating LLM-based reasoning into user interest mining and item tag prediction, it suffers from …

Development and Validation of a Nomogram for Predicting Specific Mortality Risk After Surgery for Locally Advanced Rectal Cancer: Studies Based on SEER Database and External Validation Cohorts

Shufa Tan, Shuang Liu, Yunyi Yang, Yulai Yin et autres

Introduction Rectal cancer, characterized by a high global incidence rate, is a significant malignancy. This study aimed to develop a competing risk model utilizing the SEER database to estimate the risk of cancer-specific mortality in patients diagnosed with locally advanced rectal cancer …

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Factors influencing recurrence of preeclampsia in pregnant women with a history of preeclampsia and the establishment of a predictive model

Hui Dong, Jie Song, Yan‐Ju Jia, Hongyan Cui et autres

OBJECTIVES: To establish and verify the prediction model of recurrent preeclampsia (PE) in pregnant women with a history of PE. METHODS: Totally 130 pregnant women with a history of PE from Jan 2021 to Jan 2023 were selected retrospectively. The patients were …

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Orthotopic Left Lung Transplantation in Rats

Xiaohua Wang, Yi Lü, Wenshan Zhong, Jiang Shi et autres

The rat left lung orthotopic transplantation model is an essential tool in lung transplant research. Although lung transplantation is a complex procedure, its complexity is significantly reduced with the introduction of the cuff technique. Most surgeons can master this technique after training, …

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Incidence and Factors Associated with Anaemia During Pregnancy in China: A Multicentre Prospective Cohort Study

Xiaosong Zhang, Xueyin Wang, Juan Juan, Di Gao et autres

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Prenatal progesterone treatment modulates fetal brain transcriptome and impacts adult offspring behavior in mice

Shuang Liang, Ying Zhao, Xiuwei Liu, Yan Wang et autres

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Quantitative evaluation of Kaiser score in diagnosing breast dynamic contrast-enhanced magnetic resonance imaging for patients with high-grade background parenchymal enhancement

Hui Wang, Ling Gao, Xu Chen, Shou-Ju Wang

Background: High-grade background parenchymal enhancement (BPE), including moderate and marked, poses a considerable challenge for the diagnosis of breast disease due to its tendency to increase the rate of false positives and false negatives. The purpose of our study was to explore …

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ACCURACY OF NEW INTRAOCULAR LENS CALCULATION FORMULAE IN EYES UNDERGOING SILICONE OIL REMOVAL/PARS PLANA VITRECTOMY-CATARACT SURGERY

Xu Chen, He Zhao, Yufei Xu, Zuoxin Qin et autres

PURPOSE: To investigate the performance of novel intraocular lens calculation formulae (Barrett Universal II, Emmetropia Verifying Optical, and Kane) and conventional formulae (Haigis, Hoffer Q, Holladay 1, and Sanders-Retzlaff-Kraff/T [SRK/T]) in patients who underwent pars plana vitrectomy or silicone oil removal combined …

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Progesterone Changes the Pregnancy-Induced Adaptation of Cardiomyocyte Kv2.1 Channels via MicroRNA-29b

Shuang Liang, Yushuang Sun, Lu Li, Yao Long et autres

The cardiovascular system adaptation occurs during pregnancy to ensure adequate maternal circulation. Progesterone (P4) is widely used in hormone therapy to support pregnancy, but little is known about its effects on maternal cardiac function. In this study, we investigated the cardiac repolarization …

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hsa_circWDR37_016 Regulates Hypoxia-Induced Proliferation of Pulmonary Arterial Smooth Muscle Cells

Shanshan Li, Shuang Liang, Yao Long, Xu Chen et autres

Pulmonary arterial hypertension (PAH) is characterized by abnormal remodeling of pulmonary vessel walls caused by excessive pulmonary arterial smooth muscle cell (PASMC) proliferation. Our previous clinical studies have demonstrated the importance of the downregulated circRNA in PAH. However, the role of upregulated …

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Insertion/deletion polymorphism at angiotensin-converting enzyme gene in PTSD individuals and their reciprocal effects on blood pressure

Lingnan Kong, Yi Lin Shen, Yong Li Chen, Xu Chen et autres

Objectives The aim of the present study was to investigate relationships between insertion/deletion (I/D) polymorphism at angiotensin-converting enzyme gene (ACE) and post-traumatic stress disorder (PTSD), as well as their interactions on blood pressure.Methods Variants of ACE I/D were identified by polymerase chain …

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Discriminating invasive adenocarcinoma among lung pure ground-glass nodules: a multi-parameter prediction model

Fuying Hu, Haihua Huang, Yunyan Jiang, Minxiang Feng et autres

BACKGROUND: Patients with consistent lung pure ground-glass nodules (pGGNs) have a high incidence of lung adenocarcinoma that can be classified as adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), or invasive adenocarcinoma (IAC). Regular follow-up is recommended for AIS and MIA, while …

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