Xinming Liang

Performance comparison of four exome capture platforms on DNBSEQ-Series high throughput sequencer

Meiyan Li, Xinshi Yang, Xinming Liang, Zheng Jia et autres

Whole exome sequencing (WES) technology has become a prevalent methodology in the field of human genetics research, providing an effective and affordable alternative to identify causative genetic mutations in genomic exon regions. This study focuses on the comparative assessment of four commercially …

cn, Botswana (code pays fourni par la source)

Application Research on the Integration of Indoor UWB Positioning Base Station and Outdoor RTK Positioning Base Station in Substation

Xiang Zhang, Hong Cai, Xinming Liang, Huixuan Xu

In the substation environment of the power system, accurate positioning technology is of great significance for ensuring personnel safety, improving operation and maintenance efficiency, and realizing intelligent management. This paper deeply explores the application of the fusion of indoor UWB positioning base …

cn (code pays fourni par la source)

Performance evaluation of structural variation detection using DNBSEQ whole-genome sequencing

Junhua Rao, Huijuan Luo, Dan An, Xinming Liang et autres

BACKGROUND: DNBSEQ platforms have been widely used for variation detection, including single-nucleotide variants (SNVs) and short insertions and deletions (INDELs), which is comparable to Illumina. However, the performance and even characteristics of structural variations (SVs) detection using DNBSEQ platforms are still unclear. …

cn (code pays fourni par la source)

Performance evaluation of structural variation detection using DNBSEQ whole-genome sequencing

Junhua Rao, Huijuan Luo, Dan An, Xinming Liang et autres

DNBSEQ platforms have been widely used for variation detection, including single-nucleotide variants and short insertions and deletions, comparable to Illumina. However, the performance of structural variations (SVs) detection using DNBSEQ platforms remains unclear. We assessed SV detection using 40 tools on eight …

cn (code pays fourni par la source)

S100A4 mediates the accumulation and functions of myeloid-derived suppressor cells via GP130/JAK2/STAT3 signaling in acute myeloid leukemia

Yu‐Hui Peng, Jian Zhang, Ting Zhang, Chanjuan Wang et autres

cn (code pays fourni par la source)

A 24-30 GHz 6-Bit GaN HEMT Digital Attenuator for Millimeter-Wave Phased Array Systems

Wei Cheng, Jinfeng Chen, Xinming Liang, Zhihao Zhang

A 24-30 GHz 6-bit digital attenuator for millimeter-wave phased array systems based on a 100-nm gallium-nitride-silicon (GaN-on-Si) technology, is presented. To improve insertion loss (IL) and attenuation accuracy, switched-π/T improved structures are employed in this design. The cascade sequence of the attenuation …

cn (code pays fourni par la source)

Lycorine induces apoptosis of acute myeloid leukemia cells and inhibits triglyceride production via binding and targeting FABP5

Xinming Liang, Wenli Fu, YuHui Peng, Ting Zhang et autres

cn (code pays fourni par la source)

Depletion of stem non-structural carbohydrates supports release of lateral branches from apical control in Quercus mongolica seedlings

Xiaoyi Han, Xinming Liang, Sujuan Ma, Yu Wang et autres

cn (code pays fourni par la source)

Cytarabine‐induced TNFα promotes the expansion and suppressive functions of myeloid‐derived suppressor cells in acute myeloid leukaemia

Hua Bai, Yu‐Hui Peng, Yi Li, Wenli Fu et autres

Acute myeloid leukaemia (AML) is very common haematopoietic malignancies with poor prognosis. Chemotherapy is still a mainstay therapy for AML patients. AML microenvironment plays critical roles in therapy response. However, the role of chemotherapy in AML microenvironment is poorly understood. In this …

cn (code pays fourni par la source)

Microbiota–muscle/immune interactions in rhesus macaque under simulated microgravity revealed by integrated multi‐omics analysis

Peng Zhang, Libin Shao, Jie Zhang, Lu Wang et autres

Abstract Background Long‐term exposure to microgravity during spaceflight has adverse effects on human health including muscle atrophy, impaired immune function, and alterations in gut microbiome profile. Gut microorganisms influence a wide range of host biological processes, but their interactions with skeletal muscle …

cn, Botswana, mo (code pays fourni par la source)

Two divergent haplotypes from a highly heterozygous lychee genome suggest independent domestication events for early and late-maturing cultivars

Guibing Hu, Junting Feng, Xu Xiang, Jiabao Wang et autres

Lychee is an exotic tropical fruit with a distinct flavor. The genome of cultivar 'Feizixiao' was assembled into 15 pseudochromosomes, totaling ~470 Mb. High heterozygosity (2.27%) resulted in two complete haplotypic assemblies. A total of 13,517 allelic genes (42.4%) were differentially expressed …

cn, sg, ee, id, us, fr, ca (code pays fourni par la source)

Robust Benchmark Structural Variant Calls of an Asian Using State-of-the-Art Long-Read Sequencing Technologies

Xiao Du, Lili Li, Fan Liang, Sanyang Liu et autres

The importance of structural variants (SVs) for human phenotypes and diseases is now recognized. Although a variety of SV detection platforms and strategies that vary in sensitivity and specificity have been developed, few benchmarking procedures are available to confidently assess their performances …

cn (code pays fourni par la source)