Accès ouvert
2026
article
OpenAlex
Marius Huehn, Lea Willemsen, Matthias Manfred Deininger, Judith Huth et autres
Abstract Background Lung-protective ventilation (LPV) reduces mortality in ARDS, but adherence remains incomplete and women and shorter patients disproportionately receive tidal volumes above predicted-body-weight (PBW)-based targets. The relative associations of recorded sex and body height with this disparity remain uncertain. Methods Retrospective …
de
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Accès ouvert
2026
article
OpenAlex
Marius Huehn, Lea Willemsen, Matthias Manfred Deininger, Judith Huth et autres
Additional file 1. Supplement — eFigures 1–5 and eTables 1–8, including triplet-combination adherence summaries, sensitivity analysis at the 4–6 mL/kg PBW threshold, ARDS-severity-stratified analyses, adjusted VT and mechanical-power models, the paired formula sensitivity analysis, and adjusted ICU mortality
de
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Marius Huehn, Lea Willemsen, Matthias Manfred Deininger, Judith Huth et autres
Additional file 1. Supplement — eFigures 1–5 and eTables 1–8, including triplet-combination adherence summaries, sensitivity analysis at the 4–6 mL/kg PBW threshold, ARDS-severity-stratified analyses, adjusted VT and mechanical-power models, the paired formula sensitivity analysis, and adjusted ICU mortality
de
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Accès ouvert
2026
article
OpenAlex
Matthias Manfred Deininger, Diana Freund, Louisa Jahnke, Kathrin Magdalena Schumann-Stoiber et autres
BACKGROUND: Intensive care unit (ICU) demand is increasing, while healthcare professional shortages and turnover threaten capacity, care quality, and patient safety. This nationwide survey quantified intention to stay (ITS), leave (ITL), or being undecided among ICU professionals in Germany and assessed associated …
de
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Accès ouvert
2026
article
OpenAlex
Matthias Manfred Deininger, Paul Wassersteiner, Nico Haehn, Judith Huth et autres
PURPOSE: Stress-induced hyperglycemia is a frequent metabolic response to polytrauma. To date, studies primarily analyzed its association with mortality; however, its effect on functional outcomes remain unclear. This study investigated the association between sustained hyperglycemia across metabolic phases and functional outcomes in …
de
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Accès ouvert
2026
article
OpenAlex
Matthias Manfred Deininger, Magdalena Ralser, Nico Haehn, Marius Huehn et autres
BACKGROUND: Traumatic brain injury (TBI) is a major cause of trauma-related deaths. Systemic glucose and lactate levels reflect secondary metabolic derangements over time; however, most prognostic models rely on admission values. This study compared static and longitudinal indices of glucose, lactate, and …
de
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Accès ouvert
2026
other
OpenAlex
Matthias Manfred Deininger, Magdalena Ralser, Nico Haehn, Marius Huehn et autres
Abstract Background Traumatic brain injury (TBI) is a major cause of trauma-related deaths. Systemic glucose and lactate levels reflect secondary metabolic derangements over time; however, most prognostic models rely on admission values. This study compared static and longitudinal indices of glucose, lactate, …
de
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Matthias Manfred Deininger, Magdalena Ralser, Nico Haehn, Marius Huehn et autres
Additional file 1.
de
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Matthias Manfred Deininger, Magdalena Ralser, Nico Haehn, Marius Huehn et autres
Abstract Background Traumatic brain injury (TBI) is a major cause of trauma-related deaths. Systemic glucose and lactate levels reflect secondary metabolic derangements over time; however, most prognostic models rely on admission values. This study compared static and longitudinal indices of glucose, lactate, …
de
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Matthias Manfred Deininger, Magdalena Ralser, Nico Haehn, Marius Huehn et autres
Additional file 1.
de
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Nico Haehn, Marius Huehn, Magdalena Ralser, Dmitrij Ziles et autres
BACKGROUND: Critically ill burn patients face severe metabolic stress, divided into early ebb and late flow phases, causing dysglycemia. While detrimental effects of hyper- and hypoglycemia in burn patients have been reported over the entire stay, its impact during the ebb and …
de
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Arnhold Lohse, Felix Röhren, Philip von Platen, Carl-Friedrich Benner et autres
Mechanical ventilation maintains the gas exchange of patients in the intensive care unit which is life-saving, but prolonged ventilation results in diaphragm atrophy. Phrenic nerve stimulation can keep the diaphragm active so that atrophy might be avoided. To use phrenic nerve stimulation …
de
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