Hazumu Nagata

Heterogeneity of necrotizing enterocolitis associated with congenital heart disease: a comparative study of preoperative and postoperative clinical phenotypes

Shoma Koga, Ko Miyazaki, Akihiko Tamaki, Ayako Kuraoka et autres

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A child with lung abscess and toxic shock syndrome fulfilling criteria for Kawasaki disease caused by Panton-Valentine leucocidin–producing ST22methicillin-resistant Staphylococcus aureus

Taisei Ayaka, Zenpei Kano, Wataru Tanaka, Yuiko Nakabayashi et autres

This is a PDF of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability.This version will undergo additional copyediting, typesetting and review before it is published in its final …

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Rapidly progressive vasculopathy in an infantile-onset fibromuscular dysplasia

Eriko Hatai, Yuri Sonoda, Motoshi Sonoda, Kei Nishiyama et autres

BACKGROUND: Fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disease that predominantly affects renal and cerebral vessels, causing renovascular hypertension and stroke. Because FMD occurs extremely rarely in early childhood, the clinical presentation at onset and the long-term outcome of childhood-onset FMD remain …

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Clinical and virological impacts of human parvovirus B19 epidemics on fulminant myocarditis in childhood

Yoshitomo Motomura, Ryuichi Takemoto, Kenichiro Yamamura, Hazumu Nagata et autres

BACKGROUND: Outbreaks of pediatric myocarditis and increased activity of human parvovirus B19 (B19V) have been reported worldwide following the coronavirus disease 2019 (COVID-19) pandemic. However, the direct association between prevalent erythema infectiosum and fulminant myocarditis (FM) remains elusive because of the lack …

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Population‐Based Study of Prenatal Detection of Critical Congenital Heart Disease in Kyu‐Yama Region of Japan

Hazumu Nagata, Yuzo Kitadai, Takuya Hara, Mitsuhisa Shinya et autres

BACKGROUND: The prenatal detection rate (PDR) of congenital heart disease (CHD) has been scarcely reported in Japan. This study aimed to investigate PDR of critical CHD in a region of Japan and to evaluate the impact of prenatal diagnosis on postnatal mortality …

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Strain elastography for detecting advanced Fontan-associated liver disease: a retrospective study

Koji Imoto, Takeshi Goya, Yuki Azuma, Tomonobu Hioki et autres

The Fontan procedure has improved the prognosis of patients with a functional single ventricle; however, late complications—including Fontan-associated liver disease (FALD)—have surfaced as clinical concerns. FALD with signs of portal hypertension has been defined as advanced FALD (aFALD) due to its poor …

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Extrahepatic portosystemic shunt concealed in congenital heart disease and neurodevelopmental disorder: a case report

Toshinobu Ifuku, Hazumu Nagata, Yusaku Nagatomo, Ichiro Sakamoto et autres

Background: Neurodevelopmental disorders (NDDs) are often associated with congenital heart diseases (CHDs). Congenital portosystemic shunt (CPSS) is a rare abnormality of the portal system in which toxic substances that are not adequately metabolized by the liver circulate throughout the body and can …

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Successful Kidney Transplantation for Bilateral Renal Hypoplasia With Ebstein Disease

Sosuke Kimura, Yusaku Nagatomo, Kei Nishiyama, Hazumu Nagata et autres

BACKGROUND: Patients with renal hypoplasia are often associated with congenital heart disease (CHD). During the perioperative period of kidney transplantation (KTx), sufficient circulation volume is required to maintain renal blood flow in the donor kidney. However, little is known about the indication …

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Abstract 4136627: Development of a biomarker to predict refractory cases in Kawasaki disease patients -towards the development of diagnostic kit-

Yukako Yoshikane, Ryuji Fukazawa, Watanabe Makoto, Atsuhito Takeda et autres

Introduction: Kawasaki disease (KD), which is the most common multisystem vasculitis with unknown causes in childhood, causes coronary artery lesions (CALs). Treatment with a high dose of intravenous immunoglobulin (IVIG) is the most effective therapy for the acute phase of KD. However, …

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Abstract 4139896: Prognosis of Pulmonary Arterial Hypertension after Treatment for Congenital Portosystemic Shunt in Children

Ryohei Matsuoka, Hazumu Nagata, Masaru Kobayashi, Kiyoshi Uike et autres

Introduction: Congenital portosystemic shunt (CPSS) is a rare vascular malformation which forms shunts between the portal and systemic veins. Pulmonary arterial hypertension (PAH) in CPSS patients heightens mortality risk. Research Questions: It remains unclear which patients’ characteristics are associated with the developing …

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Dural arteriovenous fistulae in a 6-year-old girl with trisomy 21 and congenital heart disease

Toshiya Ishikura, Yuri Sonoda, Kenta Kajiwara, Pin Fee Chong et autres

Dural arteriovenous fistula (DAVF) represents a pathological group of intracranial shunts arising from the dural artery to venous sinus and veins. Childhood-onset DAVF is generally considered to be poor in prognosis, whereas only limited information is available for the onset and long-term …

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The immunoreactive signature of monocyte-derived dendritic cells from patients with Down syndrome

Kentaro Nakashima, Takashi Imai, Akira Shiraishi, Ryoko Unose et autres

The clinical spectrum of Down syndrome (DS) ranges from congenital malformations to premature aging and early-onset senescence. Excessive immunoreactivity and oxidative stress are thought to accelerate the pace of aging in DS patients; however, the immunological profile remains elusive. We investigated whether …

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