Keishi Yamashita

Unrecognized nocturnal hypoglycemia and glucose variability after gastrectomy: A prospective exploratory pilot study using continuous glucose monitoring with nutritional intervention

Motohiro Chuman, Kota Okuno, Keishi Yamashita, Shohei Fujita et autres

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The phase I trial of preoperative short-course chemoradiotherapy with S-1/irinotecan and short-course radiation in locally advanced lower rectal cancer (SHOWTIME study)

Ken Kojo, Toshimichi Tanaka, Takahiro Yamanashi, Hirohisa Miura et autres

BACKGROUND: A phase I study was conducted to determine the optimal dose of irinotecan in short-course chemoradiotherapy (SCCRT) using S-1/irinotecan and short-course radiotherapy (SCRT) for the development of a new total neoadjuvant therapy (TNT) regimen that is safe, effective, and has a …

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Additional file 1 of The phase I trial of preoperative short-course chemoradiotherapy with S-1/irinotecan and short-course radiation in locally advanced lower rectal cancer (SHOWTIME study)

Ken Kojo, Toshimichi Tanaka, Takahiro Yamanashi, Hirohisa Miura et autres

Supplementary Material 1

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Additional file 1 of The phase I trial of preoperative short-course chemoradiotherapy with S-1/irinotecan and short-course radiation in locally advanced lower rectal cancer (SHOWTIME study)

Ken Kojo, Toshimichi Tanaka, Takahiro Yamanashi, Hirohisa Miura et autres

Supplementary Material 1

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Appetite-preserving gastrectomy attenuates early postoperative deterioration of bone quality after surgery in esophagogastric junction cancer

Hiroki Harada, Hiroyuki Minoura, Kota Okuno, Kaori Kawana et autres

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Delayed Initiation of Postoperative S-1 Adjuvant Chemotherapy Worsens Prognosis After Gastric Cancer Recurrence

KEIJI NISHIBEPPU, S. Sakuramoto, Yosuke Morimoto, Kazuaki Matsui et autres

Background/Aim: Previous reports revealed the negative prognostic factors for patients with gastric cancer (GC) who received curative surgery plus postoperative S-1 chemotherapy. However, there were few reports on the survival time of patients after the recurrence of GC. Therefore, this study aimed …

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A phase I/II clinical trial of neoadjuvant docetaxel/oxaliplatin/S‑1 (DOS) combination therapy for gastroesophageal junction adenocarcinoma

Koshi Kumagai, Kei Hosoda, Chikatoshi Katada, Kenji Ishido et autres

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Feasibility of endoscopic response evaluation after induction chemotherapy for determining treatment strategies in esophageal cancer: a post hoc analysis of the CROC trial

Chikatoshi Katada, Akira Yokoyama, Akinori Watanabe, Yasuo Hamamoto et autres

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Comparative Oncology: Cross-Sectional Single-Cell Transcriptomic Profiling of the Tumor Microenvironment Across Seven Human Cancers

Riku Okamoto, Kota Okuno, Akiko Watanabe, Kanako Naito et autres

Background/Objectives: To elucidate the differential transcriptional and intercellular signaling features of tumor components across various cancers, we conducted a comparative analysis using single-cell RNA sequencing (scRNA-seq). This technology enables detailed characterization of tumor ecosystems and may explain variations in tumor behavior among …

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Laparoscopic and Endoscopic Cooperative Surgery for Gastric Cancer as an Alternative Treatment in Elderly Patients: A Prospective Observational Study

Marie Washio, Keishi Yamashita, Takuya Wada, Mikiko Sakuraya et autres

Aim: Laparoscopic and endoscopic cooperative surgery (LECS) is a minimally invasive procedure that preserves gastric function and reduces complications. Although widely applied for gastrointestinal stromal tumors, its role in gastric cancer remains uncertain. We prospectively evaluated LECS as an alternative for elderly …

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Clinical utility impact of DNA-based cytology using droplet digital methylation-specific PCR in gastric cancer

Hiroki Harada, Takafumi Soeno, Akira Ooki, Kanako Naito et autres

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ASO Visual Abstract: SPARC Expression Induces COL1A1/COL3A1 Representing Aggressive Molecular Cancer-Associated Fibroblast Signatures and CSF1-Mediated Cancer Invasion in Colorectal Cancer

Yusuke Nie, Yoshiki Fujiyama, Shumpei Shibaki, Riku Okamoto et autres

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