Accès ouvert
2026
article
OpenAlex
Alice Gichemi, Noa Esther Wijnen, Eline Kormelink, Isaac Osore et autres
INTRODUCTION: Childhood cancer presents significant challenges in low- and middle-income countries (LMICs), as survival rates remain substantially low. Supportive care, including nutritional support and infection prevention plus management, is crucial in improving outcomes of childhood cancer patients. To develop evidence-based interventions improving …
Kenya, nl, Malawi, us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Festus Muigai Njuguna, Carole Jesang Kilach, Cyrus Njuguna, Erick Ayaye et autres
Background: Globally, approximately 515,000 infants with Sickle Cell Disease (SCD) are born every year. Approximately 80% of these cases occur in Sub‑Saharan Africa (SSA) annually, including 14,000 newborns in Kenya. In SSA, 50%–80% of children will die before the age of 5 …
Kenya, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Helen Wu Li, Jesse Kiprono Too, Sarah Nyariki, C. Nathan Nessle et autres
BACKGROUND: Capacity for elective general surgical care is an important reflection of a health system's ability to meet a population's surgical needs and is currently known to be inadequate in many low- and middle-income countries. Patient agency is a key, understudied factor …
Kenya, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Lenah Nyamusi, Kenneth M. Busby, Sarah Kinja, Festus Muigai Njuguna et autres
Children with cancer in lower-middle-income countries (LMICs) are at increased risk of dying from infections. Prompt treatment of fever episodes improves outcomes, yet poorly described challenges impair management. This qualitative study explored healthcare provider perspectives on barriers to and facilitators of inpatient …
us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Everlyn Kisembe, C. Nathan Nessle, Julia C. Dettinger, Lenah Nyamusi et autres
Children with cancer in lower-middle-income countries (LMICs) are at increased risk of dying from infections. Prompt treatment of fever episodes improves outcomes, yet poorly described challenges impair management. This qualitative study explored healthcare provider perspectives on barriers to and facilitators of inpatient …
Kenya, us, nl
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Terry A. Vik, Festus Muigai Njuguna, C. Nathan Nessle, Gilbert Olbara et autres
Compared to febrile neutropenia (FN), non-neutropenic fever (NNF) episodes in children with cancer have not been associated with severe outcomes. Risk factors for severe outcomes in FN and NNF episodes in children with cancer from low-middle-income countries (LMIC) are incompletely described. A …
us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Samuel Kipchumba, Kenneth M. Busby, Dennis Njenga, Julia C. Dettinger et autres
Introduction Compared to febrile neutropenia (FN), non-neutropenic fever (NNF) episodes in children with cancer have not been associated with severe outcomes. Risk factors for severe outcomes in FN and NNF episodes in children with cancer from low-middle-income countries (LMIC) are incompletely described. …
Kenya, us, nl
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Leonora R. Slatnick, David J. Hoogstra, Brian T. Fisher, Joshua Wolf et autres
INTRODUCTION: While clinical practice guidelines (CPGs) for pediatric oncology infection prophylaxis and management exist, few data describe actual management occurring at pediatric oncology centers. METHODS: An electronic survey querying infection management practices in nontransplant pediatric oncology patients was iteratively created by the …
us, ca
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Gilbert Olbara, Festus Muigai Njuguna, Mary Ann Etling, Sandra Langat et autres
replication of ECHO programs in LMICs to improve education and public health outcomes.In conclusion, as the ECHO model continues to connect specialty experts with HCPs in medically isolated settings for education and partnership, patient care will continue to benefit.These three patients demonstrate …
Kenya, us, nl
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Eleanor Smeallie, Sung Won Choi, Rajen J. Mody, Timothy C. Guetterman et autres
INTRODUCTION: Many febrile neutropenia (FN) episodes are low risk (LR) for severe outcomes and can safely receive less aggressive management and early hospital discharge. Validated risk tools are recommended by the Children's Oncology Group to identify LR FN episodes. However, the complex …
us
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Zhiguo Zhao, Pratik A. Patel, Leonora R. Slatnick, Anna Sitthi-Amorn et autres
PURPOSE The optimal management of fever without severe neutropenia (absolute neutrophil count [ANC] ≥500/µL) in pediatric patients with cancer is undefined. The previously proposed Esbenshade Vanderbilt (EsVan) models accurately predict bacterial bloodstream infections (BSIs) in this population and provide risk stratification to …
us, lb, au
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
C. Nathan Nessle, Festus Muigai Njuguna, Julia C. Dettinger, Mercy Ndung’u et autres
INTRODUCTION: Febrile neutropenia is an oncological emergency in children with cancer, associated with serious infections and complications. In low-resourced settings, death from infections in children with cancer is 20 times higher than in high-resourced treatment settings, thought to be related to delays …
us, Kenya
(code pays fourni par la source)