Cindy M. Chang

Population Assessment of Tobacco and Health (PATH) Study Wave 1 and Wave 4 Biomarker Cores and available biomarker data: design and methods

F. Patrick Hubbard, Jean D. Opsomer, Kathryn C. Edwards, Sylvia M Dohrmann et autres

Abstract Introduction The Population Assessment of Tobacco and Heath (PATH) Study is a nationally representative longitudinal cohort study on US tobacco use and its effects on health. It is unique among longitudinal studies of tobacco in that it collects biospecimens from representative …

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Tobacco-related urinary biomarkers and lung cancer risk in women, a case-cohort analysis

Mahdi Nalini, Katie M. O’Brien, Antonia M. Calafat, Lanqing Wang et autres

BACKGROUND: The constituents of tobacco smoke that specifically contribute to lung cancer risk have yet to be fully identified. We evaluated associations between biomarkers of potentially harmful constituents-polycyclic aromatic hydrocarbons, tobacco-specific nitrosamines, nicotine, and volatile organic compounds-and lung cancer incidence among US …

us, th, ua (code pays fourni par la source)

Consistency of Biomarkers of Exposure in the Population Assessment of Tobacco and Health Study from Samples Taken 3 to 5 Years Apart

David L. Ashley, Wanzhe Zhu, Deepak Bhandari, Lanqing Wang et autres

INTRODUCTION: Urinary biomarkers are useful in characterizing exposure to harmful and potentially harmful constituents of tobacco products and linking exposure to health outcomes. However, the consistency/reproducibility of many urinary biomarkers over long periods is unknown. METHODS: Among people who exclusively used cigarettes …

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Heart spheroids from primary cells for studying cardiac development

Cindy M. Chang, Juan Xu, Shirley H. L. Chang, Guang Li

Abstract Organoids can be broadly classified based on their source: either from primary cells or from in vitro stem cell differentiation. Organoids derived from primary cells have been developed for various organs such as the liver, intestine, and colon, demonstrating significant value …

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Electronic Nicotine Delivery Systems Use and Nicotine Exposure Among Adults Who Use ENDS Alone or With Cigarettes: The Population Assessment of Tobacco and Health Study 2013–2019

Kathryn C. Edwards, Katherine V. Garcia-Rosales, Maciej Lukasz Goniewicz, David L. Ashley et autres

INTRODUCTION: Evaluating nicotine exposure (total nicotine equivalents-2; TNE-2) changes over time can provide data on the public health impact of electronic nicotine delivery systems (ENDS). This study describes TNE-2 levels of those who use ENDS with or without cigarettes from 2013-2019, and …

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Treatments for Depression for Older Adults Living in Long-Term Care: A Systematic Review and Network Meta-Analysis

Kayla Atchison, Peter Hoang, Daria Merrikh, Cindy M. Chang et autres

OBJECTIVE: To assess the comparative efficacy of interventions on depressive symptoms and disorders in older adults living in long-term care (LTC). DESIGN: Systematic review and network meta-analysis. SETTING AND PARTICIPANTS: Older adults living in LTC or equivalent settings. METHODS: We searched 6 …

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Exposure to volatile organic compounds and chronic respiratory disease mortality, a case-cohort study

Mahdi Nalini, Hossein Poustchi, Deepak Bhandari, Benjamin C. Blount et autres

BACKGROUND: Chronic respiratory diseases (CRDs) are the third leading cause of death worldwide. Data of the associations between specific volatile organic compounds (VOCs), a major component of air pollution and tobacco smoke, and subsequent CRD mortality in the general population are scarce. …

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Gut microbiota modulation in cardiac cell therapy with immunosuppression in a nonhuman primate ischemia/reperfusion model

Hung-Chih Chen, Yu‐Che Cheng, Marvin L. Hsieh, Po‐Ju Lin et autres

Gut microbiota affect transplantation outcomes; however, the influence of immunosuppression and cell therapy on the gut microbiota in cardiovascular care remains unexplored. We investigated gut microbiota dynamics in a nonhuman primate (NHP) cardiac ischemia/reperfusion model while under immunosuppression and receiving cell therapy …

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Correction: Biomarkers of Inflammation and Oxidative Stress among Adult Former Smoker, Current E-Cigarette Users— Results from Wave 1 PATH Study

Carol H. Christensen, Joanne T. Chang, Brian L. Rostron, Hoda T. Hammad et autres

Supplementary Materials and Methods from Biomarkers of Inflammation and Oxidative Stress among Adult Former Smoker, Current E-Cigarette Users—Results from Wave 1 PATH Study

Carol H. Christensen, Joanne T. Chang, Brian L. Rostron, Hoda T. Hammad et autres

Description of biomarker assays

Data from Biomarkers of Inflammation and Oxidative Stress among Adult Former Smoker, Current E-Cigarette Users—Results from Wave 1 PATH Study

Carol H. Christensen, Joanne T. Chang, Brian L. Rostron, Hoda T. Hammad et autres

AbstractBackground: Former smokers who currently use e-cigarettes have lower concentrations of biomarkers of tobacco toxicant exposure than current smokers. It is unclear whether tobacco toxicant exposure reductions may lead to health risk reductions. Methods: We compared inflammatory biomarkers (high-sensitivity C-reactive protein, IL6, …

Additional file 1 of Exposure to volatile organic compounds and chronic respiratory disease mortality, a case-cohort study

Mahdi Nalini, Hossein Poustchi, Deepak Bhandari, Benjamin C. Blount et autres

Supplementary Material 1

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