Carmela Marseglia

Extracorporeal dialysis: techniques and adequacy

C. Donadio, A. Kanaki, Adoración Martín-Gómez, S. Garcia et autres

formulas for spKt/V and urea reduction ratio (URR).Chart real-time Kt/V or URR is showing during HD session.Study S1: 34 uremic patients on chronic HD therapy three times/w were included (15 women, 19 men; mean age 57.5 years [26-85]; blood flow (Qb) ranged …

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Effetti della sovraespressione di ferritina mitocondriale in precursori eritroidi normali

Serena Marra, Agnese Filocco, Erica Travaglino, Anna Gallì et autres

La ferritina mitocondriale (FtMt) è una isoforma ferritinica omopolimerica a localizzazione caratteristicamente mitocondriale. Nell’uomo è espressa a livello del sistema nervoso, miocardico, renale, testicolare, ossia tessuti ad elevato consumo di energia, ma anche nei sideroblasti ad anello in corso di anemia sideroblastica. …

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The Effects of Mitochondrial Ferritin Expression in Normal and Sideroblastic Erythropoiesis.

Matteo Giovanni Della Porta, Vittorio Rosti, Anna Gallì, Erica Travaglino et autres

Abstract Abstract 736 In erythroid cells from patients with refractory anemia with ringed sideroblasts (RARS), the expression of mitochondrial ferritin (MtF) - encoded by the nuclear FTMT gene located on chromosome 5q21.3 - occurs at a very early stage of differentiation and …

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Flow cytometry evaluation of erythroid dysplasia in patients with myelodysplastic syndrome

Matteo Giovanni Della Porta, Luca Malcovati, Rosangela Invernizzi, Erica Travaglino et autres

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Mitochondrial Ferritin Expression and Clonality of Hematopoiesis in Patients with Refractory Anemia with Ringed Sideroblasts.

Matteo Giovanni Della Porta, Luca Malcovati, Anna Gallì, Sabrina Boggi et autres

Abstract Sideroblastic anemias are a heterogeneous group of disorders that have in common the presence of erythroblasts with iron-loaded mitochondria defined as ringed sideroblasts. We have previously demonstrated that mitochondrial iron deposition in these disorders is in the form of mitochondrial ferritin …

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Evaluation of Progenitor Cells (CFU-GM, CFU-GEMM, BFU-E, CD34+ Cells) and White Blood Cells in Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma Treated with Rituximab-CHOP-14 and Supported with Pegfilgrastim.

Maurizio Bonfichi, Ercole Brusamolino, Carmela Marseglia, Chiara Rusconi et autres

Abstract Purpose: To investigate the behavior of CFU-GM, CFU-GEMM, BFU-E, CD34+ cells and white blood cells before and during six courses of dose-dense immune-chemotherapy (R-CHOP-14) supported by pegfilgrastim in eight patients affected with newly diagnosed diffuse large B cell lymphoma (3 men, …

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Relationship between JAK2 V617F Mutation Status, Granulocyte CD177 mRNA Expression and CD177 Soluble Protein Level in Patients with Polycythemia Vera.

Daniela Pietra, Alessandra Balduini, Carmela Marseglia, Matteo Giovanni Della Porta et autres

Abstract A unique gain-of-function mutation of the Janus kinase 2 (JAK2) gene has been recently described in patients with polycythemia vera (PV), essential thrombocythemia and chronic idiopathic myelofibrosis [N Engl J Med. 2005 Apr 28;352(17):1779–90]. Although the currently available data clearly demonstrate …

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Pathogenetic mechanisms of hematological abnormalities of patients with MYH9 mutations

Alessandro Pecci, Ilaria Canobbio, Alessandra Balduini, Lucia Stefanini et autres

Mutations of MYH9, the gene for non-muscle myosin heavy chain IIA (NMMHC-IIA), cause a complex clinical phenotype characterized by macrothrombocytopenia and granulocyte inclusion bodies, often associated with deafness, cataracts and/or glomerulonephritis. The pathogenetic mechanisms of these defects are either completely unknown or …

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Expression, activation, and subcellular localization of the Rap1 GTPase in cord blood-derived human megakaryocytes

Alessandra Balduini, Alessandro Pecci, Paolo Lova, Nicoletta Arezzi et autres

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Expression, activation, and subcellular localization of the Rap1, GTPase in human cord blood-derived megakaryocytes.

Alessandra Balduini, Alessandro Pecci, P. Lova, Federica Benvenuto et autres

“Release” Intra- E Ost- Dialitico Di PDGF-AB

Giuseppe Cianciolo, Gabriele Donati, Antonio De Pascalis, C. Manna et autres

Abstract non disponibile

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“Release” Intra- E Ost- Dialitico Di PDGF-AB

Giuseppe Cianciolo, Gabriele Donati, Antonio De Pascalis, C. Manna et autres

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