Violeta Pérez-Rodríguez

Time to lithium: A case register study of lithium initiation in bipolar disorder

Violeta Pérez-Rodríguez, Timothy Nguyen, Katherine Beck, Emma Butler et autres

BACKGROUND: Lithium monotherapy has been recommended as first-line maintenance or long-term pharmacological therapy for bipolar disorder (BD). Previous research has linked early lithium use with better outcomes for people with BD. Despite extensive evidence as an effective treatment for BD, lithium prescribing …

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Differential effects of a single dose of Lisdexamfetamine and Guanfacine on cognitive function in children with ADHD

Sahid El Masri, Olivia S. Kowalczyk, Marion Criaud, Steve Lukito et autres

Background: Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with cognitive difficulties which improve with traditional stimulant and non-stimulant medications. However, there is limited evidence on the cognitive effects of the newer licensed stimulant lisdexamfetamine and non-stimulant guanfacine in children with ADHD. Therefore, we compared …

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Clinical Conundrum: SSRI Emergent Hypomania, a Turn in the Road to Bipolarity?

Matthew Cohen, Prateek Varshney, Jasmine Ronsisvalle, Violeta Pérez-Rodríguez

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Brain functional abnormality in drug naïve adolescents with borderline personality disorder during self- and other-reflection

Pilar Salgado‐Pineda, Marc Ferrer, Natàlia Calvo, Juan David Duque-Yemail et autres

A disturbed sense of identity is one of the major features of borderline personality disorder (BPD), which manifests early in the course of the disorder, and is potentially examinable using functional imaging during tasks involving self-reflection. Twenty-seven medication-naïve adolescent female patients with …

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Development and Predictors of Bipolar Disorder in Children and Adolescents with Depressive Disorders A Systematic Review, Meta-analysis and Meta-regression

Gonzalo Salazar de Pablo, Violeta Pérez-Rodríguez, J.M. Olivares, Javier Camacho‐Rubio et autres

BACKGROUND: Estimating the risk of developing bipolar disorder (BD) in children and adolescents (C&A) with depressive disorders is important to optimize prevention and early intervention efforts. We aimed to quantitatively examine the risk of developing BD from depressive disorders and identify factors …

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Treatment Options for Psychotic Depression in Adolescents: A Comprehensive Review

Violeta Pérez-Rodríguez, Clàudia Aymerich, Ana Catalán, Sameer Jauhar

Despite being associated with increased illness severity and suicidality compared to non-psychotic depression, psychotic depression remains under-researched, particularly in adolescents. With this article, we aim to review treatment options for psychotic depression in adolescents. We performed a multi-step narrative review, first identifying …

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Brain functional abnormality in drug naïve adolescents with borderline personality disorder during self- and other-reflection

Pilar Salgado‐Pineda, Marc Ferrer, Natàlia Calvo, Juan David Duque-Yemail et autres

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All-cause mortality risk in long-acting injectable versus oral antipsychotics in schizophrenia: a systematic review and meta-analysis

Clàudia Aymerich, Gonzalo Salazar de Pablo, Malein Pacho, Violeta Pérez-Rodríguez et autres

Patients with schizophrenia receiving antipsychotic treatment present lower mortality rates than those who do not. However, the non-adherence rate is high, which can be partially addressed using long-acting injectable (LAI) antipsychotics. The impact of LAI treatments on all-cause mortality compared to oral …

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Prevalence and Correlates of the Concurrence of Autism Spectrum Disorder and Obsessive Compulsive Disorder in Children and Adolescents: A Systematic Review and Meta-Analysis

Clàudia Aymerich, Malein Pacho, Ana Catalán, Noorulain Yousaf et autres

BACKGROUND: Autism spectrum disorder (ASD) and obsessive compulsive disorder (OCD) are two common and impairing neurodevelopmental conditions with partial symptomatic overlap. The aim of this study is to systematically and meta-analytically examine the following: (i) the prevalence of an OCD diagnosis among …

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Clínica alucinatoria secundaria a enfermedad médica: características clínicas y manejo

M. Olivé Gadea, Violeta Pérez-Rodríguez, Edoardo Caronna, Amanda Rodrí­guez Urrutia

Las alucinaciones son percepciones en ausencia del estímulo sensorial causal correspondiente. Son un síntoma característico de los trastornos psicóticos, aunque también aparecen en otras patologías como en trastornos afectivos o clínica disociativa, así como en múltiples entidades de base orgánica, principalmente en …

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Three-year prevalence of self-harm behaviors among the reasons for emergency visits of children and adolescents.

Marc Ferrer, Benjamín Lara, Natàlia Calvo, Óscar Andión et autres

Self-harm in the paediatric population is an emerging problem that has been associated with disability and an increased risk of suicide. The objective of the study is to analyse the prevalence of self-harming behaviour as a reason for paediatric emergency consultations.

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Regulatory challenges with biosimilars: an update from 20 countries

Hye‐Na Kang, Robin Thorpe, Ivana Knežević, Mary Casas Levano et autres

The World Health Organization (WHO) issued guidelines for the regulatory evaluation of biosimilars in 2009 and has provided considerable effort toward helping member states implement the evaluation principles in the guidelines into their regulatory practices. Despite this effort, a recent WHO survey …

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