Donald M. Arnold

The 2025 McMaster Immune Thrombocytopenia (ITP) Summit: insights from autoimmune hemolytic anemia

Nicole Relke, Fatema Hossain, Saifur Rahman Chowdhury, Syed Mahamad et autres

American Society of Hematology 2026 Guidelines for Immune Thrombocytopenia (ITP): Initial and Second-Line Therapy in Adults with Primary ITP

Adam Cuker, Deirdra R. Terrell, Honieh Sowdagar, Donald M. Arnold et autres

BACKGROUND: Since publication of the American Society of Hematology 2019 Guidelines for Immune Thrombocytopenia (ITP), new clinical trials have been completed and new treatments have become available. OBJECTIVE: These evidence-based guidelines from the American Society of Hematology (ASH) are a focused update …

us, ca, fr, es, rs (code pays fourni par la source)

Vein-to-vein data: what predicts platelet response?

Nicole Relke, Richard J. Cook, Donald M. Arnold

ca (code pays fourni par la source)

Guideline on the emergency management of critical bleeding in patients with immune thrombocytopenia

Saifur Rahman Chowdhury, Emily Sirotich, Gordon H Guyatt, Dimpy Modi et autres

BACKGROUND: For patients with immune thrombocytopenia (ITP), a critical bleed, such as intracranial hemorrhage or bleeding causing hemodynamic instability, requires urgent treatment to rapidly raise the platelet count and restore hemostasis. There is no standardized approach to this hematologic emergency. OBJECTIVE: The …

ca, no, us (code pays fourni par la source)

Spontaneous Heparin-Induced Thrombocytopenia after Total Hip Arthroplasty

Arielle L. Langer, Luke S. Vest, Connors Jm, Jo-Ann I. Sheppard et autres

A rare case of spontaneous heparin-induced thrombocytopenia occurred after hip arthroplasty despite no heparin exposure. Severe thromboses developed, but the patient recovered with bivalirudin and IVIG.

us, ca (code pays fourni par la source)

Exploring the immunomodulatory impacts of blood manufacturing consolidation

Amanda Kauffman, Michelle P. Zeller, Y. Liu, Jason P. Acker et autres

INTRODUCTION: The immunomodulatory consequences of blood transfusion, known as transfusion-related immune modulation (TRIM), are often not captured by hemovigilance systems. Changes to blood product manufacturing processes may impact patient outcomes. DESIGN AND METHODS: We conducted a retrospective study of hospitalized adults (≥18 …

ca (code pays fourni par la source)

Ordering policies for multi-item inventory systems with correlated demands

Zhaleh Rahimi, Douglas G. Down, Na Li, Donald M. Arnold

• - A multi-item inventory policy is proposed for correlated demands under uncertainty. • - Vector autoregressive moving average model is used to capture demand correlations. • - Closed-form order-up-to levels are derived for multiple periods and separable costs. • - The …

ca (code pays fourni par la source)

Opportunities for improving platelet transfusion practice: A large retrospective audit across 22 hospitals

Sarah Ryan, Y. Liu, Sheharyar Raza, Anne Loeffler et autres

Summary Despite evidence‐based guidelines to inform platelet transfusion practice, unnecessary platelet transfusion persists. We performed a multicentre retrospective analysis of adults admitted to general medicine, subspecialty medicine and critical care from 1 January 2017 to 30 June 2022. Platelet transfusion guideline compliance …

ca, us (code pays fourni par la source)

Factors in the Initial Resuscitation of Patients With Severe Trauma

Luís Teodoro da Luz, Keyvan Karkouti, Jo A. Carroll, Deep Grewal et autres

Importance: Patients with bleeding and coagulopathic trauma often require more transfusions and have higher mortality rates, motivating research on improving hemostatic strategies. Objective: To evaluate the replacement of clotting factors with frozen plasma (FP) or factor concentrates (fibrinogen concentrate [FC] and prothrombin …

ca, gb, de (code pays fourni par la source)

Perioperative Anemia Management in Patients Undergoing Gynaecologic Procedures: A 12-Year Multisite Study

Nadia Gabarin, Yang Liu, Mary Coll-Black, Lea Luketic et autres

OBJECTIVES: Perioperative anemia is a risk factor for adverse outcomes in surgery. The purpose of this study was to characterize perioperative red blood cell (RBC) transfusion and intravenous (IV) iron use in patients undergoing gynaecologic procedures. METHODS: This was a retrospective cohort …

ca, us (code pays fourni par la source)

Canadian donations and transfusion database ( CANDAT ): From blood donors to transfusion recipients

Sheharyar Raza, Jeannie L. Callum, Dimpy Modi, Travis Sztainert et autres

ca (code pays fourni par la source)

Critical bleeding in adults and children with immune thrombocytopenia: a multicenter cohort study

Emily Sirotich, Saifur Rahman Chowdhury, Dimpy Modi, Gordon Henry Guyatt et autres

ABSTRACT: Critical bleeding in patients with immune thrombocytopenia (ITP) is a life-threatening hematologic emergency. This study aimed to describe the frequency, management, and outcomes of critical bleeds among adults and children with ITP. We conducted a retrospective cohort study of patients with …

ca, no, us, sa, bd (code pays fourni par la source)