Natalie Thompson

Exploring Diagnostic Delays in Early Onset Colorectal Cancer in England: A Qualitative Interview Study

Natalie Thompson

This research aims to explore diagnostic delays in early onset colorectal cancer in England through semi structured interviews exploring general practitioners’ knowledge, perceptions and diagnostic decision making. The overarching goal is to generate evidence that can guide educational programmes for clinicians and …

Internet and telephone intervention to support patients discontinuing long-term antidepressants in primary care: the REDUCE research programme including RCT

Tony Kendrick, Beth Stuart, Hannah Bowers, Mahboobeh Haji Sadeghi et autres

Background There is significant concern about increasing long-term antidepressant use in Western countries, much of which is not evidence-based. Median duration of treatment is more than 2 years in the United Kingdom, and more than 10% of adults are taking antidepressants, risking …

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8034 The ‘forgotten’ preterm – assessing outcomes of late preterm infants born in a DGH and comparing against BAPM framework to identify areas of improvement

Clare M. Lloyd, Natalie Thompson, Nita Saxena

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Abstract B047: Monitoring treatment response and toxicity in BRAF V600-mutant metastatic melanoma with circulating cell-free DNA

Sidharth Jain, A. Patrick McDeed, Megan E. McNamara, Dori S Rosenstrauch et autres

Abstract Background: The DREAMseq trial (EA6134, NCT02224781) was a national multi-center randomized phase III trial coordinated by ECOG-ACRIN that found that immune checkpoint inhibitor (IO) treatment achieves improved survival outcomes compared to targeted therapy (TT) in patients with BRAF V600-mutant metastatic melanoma. …

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Correction: Internet Tool to Support Self-Assessment and Self-Swabbing of Sore Throat: Development and Feasibility Study

Mark Lown, Kirsten A. Smith, Ingrid Müller, Catherine Woods et autres

[This corrects the article DOI: 10.2196/39791.].

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Correction: Internet Tool to Support Self-Assessment and Self-Swabbing of Sore Throat: Development and Feasibility Study (Preprint)

Mark Lown, Kirsten A. Smith, Ingrid Müller, Catherine Woods et autres

UNSTRUCTURED Background: Sore throat is a common problem and a common reason for the overuse of antibiotics. A web-based tool that helps people assess their sore throat, through the use of clinical prediction rules, taking throat swabs or saliva samples, and taking …

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Enabling biocontained plant virus transmission studies through establishment of an axenic whitefly (Bemisia tabaci) colony on plant tissue culture

Wayne R. Curtis, Natalie Thompson, David Krum, Yun-Ru Chen et autres

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Depression follow-up monitoring with the PHQ-9: an open cluster-randomised controlled trial

Tony Kendrick, Christopher Dowrick, Glyn Lewis, Michael Moore et autres

Background Outcome monitoring of depression treatment is recommended but there is a lack of evidence on patient benefit in primary care. Aim To test monitoring depression using the Patient Health Questionnaire (PHQ-9) with patient feedback. Design and setting An open cluster-randomised controlled …

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Diabetes self-management education improving self-efficacy in patients with a diagnosis of type 2 diabetes

Natalie Thompson

The purpose of the QI project was to provide DSME to patients diagnosed with T2D and measure the impact on self-reported self-efficacy in four categories: nutrition, exercise, managing diabetes, and foot care. Project objectives relate to the following PICOT question: In patients …

Internet Tool to Support Self-Assessment and Self-Swabbing of Sore Throat: Development and Feasibility Study

Mark Lown, Kirsten A. Smith, Ingrid Müller, Catherine Woods et autres

BACKGROUND: Sore throat is a common problem and a common reason for the overuse of antibiotics. A web-based tool that helps people assess their sore throat, through the use of clinical prediction rules, taking throat swabs or saliva samples, and taking throat …

gb (code pays fourni par la source)

Enabling biocontained plant virus transmission studies through establishment of axenic whitefly (Bemisia tabaci) colony on plant tissue culture

Natalie Thompson, David Krum, Yun-Ru Chen, Mariela Analía Torres et autres

Abstract A colony of axenic ‘sweet potato’ whiteflies (i.e., free from culturable microorganisms) was established on tissue-cultured plants and was used to demonstrate in vitro begomovirus transmission. A co-culture system based on non-viral host cabbage (Brassica oleracea) provides for efficient maintenance of …

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Patient-reported outcome measures for monitoring primary care patients with depression: the PROMDEP cluster RCT and economic evaluation

Tony Kendrick, Christopher Dowrick, Glyn Lewis, Michael Moore et autres

Background: Guidelines on the management of depression recommend that practitioners use patient-reported outcome measures for the follow-up monitoring of symptoms, but there is a lack of evidence of benefit in terms of patient outcomes. Objective: To test using the Patient Health Questionnaire-9 …

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