Sarita Poonia

Sex-differences in airway transcriptomic signatures in asthma.

Joe Zein, Sarita Poonia, Lacey Nixon, Bo Hu et autres

To understand sex differences in asthma (A) across the ages, we assessed sex-differences in bronchial epithelial cells RNAseq data from 3 cohorts (SARP 3, GSE85567, GSE201955) and combined the results in a meta-analysis. We stratified our analysis by age (1: ≤50 years, …

us, gb (code pays fourni par la source)

Unraveling Coagulopathy in Acute Promyelocytic Leukemia: Insights from Single-Cell RNA Sequencing

Akash Maity, Sarita Poonia, N Bhattacharya, Hasmukh Jain et autres

*Corresponding author : (e-mail: syedhasanbio@yahoo.com/shasan@actrec.gov.in).

in (code pays fourni par la source)

Literature mining discerns latent disease–gene relationships

Priyadarshini Rai, Atishay Jain, Shivani Kumar, Divya Sharma et autres

MOTIVATION: Dysregulation of a gene's function, either due to mutations or impairments in regulatory networks, often triggers pathological states in the affected tissue. Comprehensive mapping of these apparent gene-pathology relationships is an ever-daunting task, primarily due to genetic pleiotropy and lack of …

in (code pays fourni par la source)

Effect of nano nitrogen and phosphorus on growth, yield and quality of ber, Ziziphus mauritiana Lam

S.L. Meena, R K Jain D K Bhardwaj, K. Pushpa, Lalit Kumar et autres

An experiment was conducted at Agricultural Research Station, Mandor, Jodhpur (Raj.) to find out the effects of nano nitrogen and phosphorus fertilizers on growth, yield and quality of ber using Factorial Randomized Block Design with 5 replications from October 2021 to March …

us (code pays fourni par la source)

Marker-free characterization of full-length transcriptomes of single live circulating tumor cells

Sarita Poonia, Anurag Goel, Smriti Chawla, N Bhattacharya et autres

The identification and characterization of circulating tumor cells (CTCs) are important for gaining insights into the biology of metastatic cancers, monitoring disease progression, and medical management of the disease. The limiting factor in the enrichment of purified CTC populations is their sparse …

in, sg, us (code pays fourni par la source)

Gene expression based inference of cancer drug sensitivity

Smriti Chawla, Anja Rockstroh, Melanie Lehman, Ellca Ratther et autres

Inter and intra-tumoral heterogeneity are major stumbling blocks in the treatment of cancer and are responsible for imparting differential drug responses in cancer patients. Recently, the availability of high-throughput screening datasets has paved the way for machine learning based personalized therapy recommendations …

in, au, ca (code pays fourni par la source)

A visual atlas of genes’ tissue-specific pathological roles

Priyadarshini Rai, Atishay Jain, Neha Jha, Divya Sharma et autres

Abstract Dysregulation of a gene’s function, either due to mutations or impairments in regulatory networks, often triggers pathological states in the affected tissue. Comprehensive mapping of these apparent gene-pathology relationships is an ever daunting task, primarily due to genetic pleiotropy and lack …

in, au (code pays fourni par la source)

Marker-free characterization of single live circulating tumor cell full-length transcriptomes

Sarita Poonia, Anurag Goel, Smriti Chawla, N Bhattacharya et autres

Abstract The identification and characterization of circulating tumor cells (CTCs) are important for gaining insights into the biology of metastatic cancers, monitoring disease progression, and medical management of the disease. The limiting factor that hinders enrichment of purified CTC populations is their …

in, au, sg, us (code pays fourni par la source)

Gene expression based inference of drug resistance in cancer

Smriti Chawla, Anja Rockstroh, Melanie Lehman, Ellca Rather et autres

Abstract Inter and intra-tumoral heterogeneity are major stumbling blocks in the treatment of cancer and are responsible for imparting differential drug responses in cancer patients. Recently, the availability of large-scale drug screening datasets has provided an opportunity for predicting appropriate patient-tailored therapies …

in, au, ca (code pays fourni par la source)

Staging System to Predict the Risk of Relapse in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

Chitrita Goswami, Sarita Poonia, Lalit Kumar, Debarka Sengupta

Over the last decade autologous stem cell transplantation (ASCT) has emerged as the standard of care in the management of Multiple Myeloma (MM). However, the cases of early relapse (within 36 months) after the stem cell rescue remains a significant challenge. For …

in (code pays fourni par la source)

Pathway Informatics

Sarita Poonia, Smriti Chawla, Sandeep Kaushik, Debarka Sengupta

in, pt (code pays fourni par la source)