Reiko Hatori

Clinical characteristics and treatment strategies for A20 haploinsufficiency in Japan: a national epidemiological survey

Mayuka Shiraki, Saori Kadowaki, Yuki Miwa, Kenichi Nishimura et autres

Background: The severity of A20 haploinsufficiency (HA20) varies, with no established clinical guidelines for treatment. This study aimed to elucidate the clinical characteristics of, and the efficacy of treatments attempted in, patients with HA20 in Japan. Methods: Clinical information on HA20 patients …

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Multiple esophageal ulcers in a pediatric case of granulomatosis with polyangiitis: A case report

Yuki Kimura, Takashi Ishige, Takuya Nishizawa, Yoshiko Igarashi et autres

A 14-year-old girl presented with diarrhea and bloody stools was initially diagnosed with infectious colitis and anal fissure. The patient was treated with antibiotics; however, the symptoms persisted and purpura appeared on the patient's lower abdomen. Abdominal computed tomography indicated diffuse wall …

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Natural history and clinical features of hepatitis C virus infection during childhood: A nationwide, observational survey in Japan

Satoshi Nakano, Mitsuyoshi Suzuki, Reiko Hatori, Tatsuki Mizuochi et autres

AIM: Few data on spontaneous clearance rates of cases of mother-to-child transmission of hepatitis C viral (HCV) infection are available in Japan. Furthermore, the treatment courses of interferon-based and direct-acting antiviral agent (DAA) therapies for children are also unclear. Our aim was …

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Efficacy and Safety of Long-Term Administration of Esomeprazole in Japanese Pediatric Patients Aged 1–14 Years with Chronic Gastric Acid-Related Disease

Masaaki Mori, Yoshiko Nakayama, Shigeo Nishimata, Tadafumi Yokoyama et autres

Purpose: To evaluate prolonged esomeprazole use in Japanese pediatric patients for reflux esophagitis (RE) maintenance therapy and prevention of gastric (GU) and/or duodenal ulcers (DU) while using non-steroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin (LDA). Methods: This multicenter, open-label, parallel-group, phase III …

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Correction: Efficacy and Safety of Long-Term Administration of Esomeprazole in Japanese Pediatric Patients Aged 1–14 Years with Chronic Gastric Acid-Related Disease

Masaaki Mori, Yoshiko Nakayama, Shigeo Nishimata, Tadafumi Yokoyama et autres

[This corrects the article on p. 274 in vol. 27, PMID: 39319279.].

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The role of serum Wisteria floribunda agglutinin-positive Mac-2 binding protein in the assessment of fibrosis in children with chronic hepatitis C

Hitoshi Tajiri, Mitsuyoshi Suzuki, Kazuhiko Bessho, Yoshinori Ito et autres

At present, noninvasive fibrosis markers are not available for the assessment of liver fibrosis in children with chronic hepatitis C. Sixty-three children with chronic hepatitis C were included. Changes in Wisteria floribunda agglutinin-positive Mac-2 binding protein (M2BPGi) levels were evaluated in l3 …

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The role of serum Wisteria floribunda agglutinin-positive Mac-2 binding protein in the assessment of fibrosis in children with chronic hepatitis C

Hitoshi Tajiri, Mitsuyoshi Suzuki, Kazuhiko Bessho, Yoshinori Ito et autres

Abstract BackgroundAt present non-invasive fibrosis markers are not available for assessment of liver fibrosis in children with chronic hepatitis C. MethodsSixty-three children with chronic hepatitis C were included. Changes in Wisteria floribunda agglutinin-positive Mac-2 binding protein (M2BPGi) levels were evaluated in l3 …

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Serological cytokine signature in paediatric patients with inflammatory bowel disease impacts diagnosis

Maiko Tatsuki, Reiko Hatori, Tomoko Nakazawa, Takashi Ishige et autres

Endoscopy is a central tool for diagnosing and evaluating paediatric inflammatory bowel diseases (PIBD), but is too invasive to be frequently repeated in young children. Furthermore, it is challenging to distinguish Crohn's disease (CD) from ulcerative colitis (UC) endoscopically. This study aimed …

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Whipple disease mimicking inflammatory bowel disease

Maiko Tatsuki, Takashi Ishige, Yoshiko Igarashi, Reiko Hatori et autres

Whipple disease is a systemic chronic infection caused by Tropheryma whipplei. Although chronic diarrhea is a common gastrointestinal symptom, diagnosis is often difficult because there are no specific endoscopic findings, and the pathogen is not detectable by stool culture. We present a …

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Interleukin 2 receptor-α expression after lymphocyte stimulation for non-IgE-mediated gastrointestinal food allergies

Hisako Yagi, Takumi Takizawa, Koichiro Sato, Takaharu Inoue et autres

Interleukin 2 receptor-a expression after lymphocyte stimulation for non-IgE-mediated gastrointestinal food allergiesDear Editor, Non-IgE-mediated gastrointestinal food allergies (non-IgE-GI-Peer review under responsibility of Japanese Society of Allergology.

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Correction to: Standard protocol devised by the Japanese Pediatric Impedance Working Group for combined multichannel intraluminal impedance-pH measurements in children

Suguru Fukahori, Hisayoshi Kawahara, Takanori Oyama, Takeshi Saito et autres

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Standard protocol devised by the Japanese Pediatric Impedance Working Group for combined multichannel intraluminal impedance-pH measurements in children

Suguru Fukahori, Hisayoshi Kawahara, Takanori Oyama, Takeshi Saito et autres

Multichannel intraluminal impedance-pH measurements (MII-pH) are useful for evaluating acid and non-acid gastroesophageal reflux (GER). However, the use of MIH-pH is not yet established in Japan. The Japanese Pediatric Impedance Working Group (Japanese-PIG) convened to devise a standard protocol for MII-pH in …

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