Takeshi Saito

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka et autres

Glioblastoma (GBM) is the most aggressive primary malignant tumor of the adult central nervous system with poor survival outcomes despite multimodal standard treatment. Tumor-treating fields (TTFields) therapy prolongs survival in patients with newly diagnosed GBM; however, sustained adherence is essential to achieve …

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Return to work and factors influencing recovery after endoscopic transsphenoidal surgery for hypothalamic and pituitary tumors

Kohei Suzuki, Yoshiteru Nakano, Masahiro Inoue, Koichiro Sato et autres

This study investigated the return-to-work (RTW) rates and associated factors following endoscopic transsphenoidal surgery (eTSS) among patients with pituitary and hypothalamic tumors in Japan. The primary research question aimed to determine the variables affecting early RTW post-surgery. A retrospective analysis was conducted …

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Growth impairment in Japanese children with inflammatory bowel disease: A multicenter prospective cohort study

Hirotaka Shimizu, Ryusuke Nambu, Nao Tachibana, Reiko Kunisaki et autres

OBJECTIVES: To investigate the prevalence and characteristics of growth impairment (GI) in children with inflammatory bowel disease (IBD). METHODS: In this prospective observational study, 402 children with ulcerative colitis (UC, n = 257) and Crohn's disease (CD, n = 145) were enrolled …

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Nelarabine‐combined chemotherapy improves outcome of T‐cell acute lymphoblastic leukemia but shows more severe neurotoxicity: JALSG T‐ ALL213 ‐O

Fumihiko Hayakawa, Naoki Mori, Kiyotoshi Imai, Yasuhisa Yokoyama et autres

We investigated the effectiveness and safety of nelarabine (NEL)-combined chemotherapy for newly diagnosed adult T-cell acute lymphoblastic leukemia (T-ALL) patients. We conducted a phase II trial, T-ALL213-O, where adult T-ALL patients aged 25 to 64 were treated by a regimen based on …

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Low Immunoglobulin G and Low Lymphocyte-Monocyte Ratio at the End of Treatment Predict Early Progression in Diffuse Large B-Cell Lymphoma

Hideki Uryu, M. Kawashima, Kazuhito Suzuki, Ryoko Fukushima et autres

Introduction The outcome of diffuse large B-cell lymphoma (DLBCL) has improved with rituximab-containing immunochemotherapy. However, some patients with DLBCL experience relapse or disease progression. Particularly, early progressive disease (EPD) influences dismal prognosis. Immunoglobulin G (IgG), absolute lymphocyte (ALC) and lymphocyte-monocyte ratio (LMR) …

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Survival impact of response within the first year in a multicenter prospective observational study of chronic GVHD in a Japanese cohort

Chikako Ohwada, Emiko Sakaida, Yusuke Takeda, Noriko Doki et autres

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Surgical outcomes of very-early-onset ulcerative colitis: retrospective comparative study with older pediatric patients

Takashi Fumita, Keita Terui, Ryohei Shibata, Ayako Takenouchi et autres

PURPOSE: The study compares the surgical outcomes of very-early-onset ulcerative colitis (VEO-UC), which is a rare disease diagnosed in pediatric patients < 6 years, with those of older pediatric patients with ulcerative colitis (UC). METHODS: A retrospective observational study of 57 pediatric …

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Surgical outcomes of very-early-onset ulcerative colitis: retrospective comparative study with older pediatric patients

Takashi Fumita, Keita Terui, Ryohei Shibata, Ayako Takenouchi et autres

Abstract Purpose The study compares the surgical outcomes of very-early-onset ulcerative colitis (VEO-UC), which is a rare disease diagnosed in pediatric patients < 6 years, with those of older pediatric patients with ulcerative colitis (UC). Methods A retrospective observational study of 57 …

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Prognosis of pediatric ulcerative colitis after infliximab failure: A multicenter registry‐based cohort study

Ryusuke Nambu, Takahiro Kudo, Nao Tachibana, Hirotaka Shimizu et autres

BACKGROUND AND AIM: Even with increasing numbers of biologic agents available for management of ulcerative colitis (UC), infliximab (IFX) retains an important place in treatment of pediatric patients with this disease. As few reports have addressed outcomes in pediatric UC patients who …

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Does Congenital Biliary Dilatation Todani Type II (Diverticular Type) Really Exist?

Takeshi Saito, Hisami Ando, Shin Ishihara, Takao Itoi et autres

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Outcomes of adult native liver survivors with biliary atresia: the current situation in Japan

Yunosuke Kawaguchi, Keita Terui, Ayako Takenouchi, Shugo Komatsu et autres

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Frequency of infiltrating regulatory T-cells in the portal tract of biliary atresia

Satoru Oita, Takeshi Saito, Rei Hashimoto, Takashi Fumita et autres

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