LINONG JI

710-P: Comparing Models for Predicting Diabetes Progression and Cardiovascular Disease in Risk Stratification and Drug Selection for Prediabetes

Song Wang, Qi Huang, Yingying Luo, LINONG JI et autres

Introduction and Objective: To compare models predicting diabetes (DM) progression or incident cardiovascular disease (CVD) in risk stratification and treatment heterogeneity identification in patients with prediabetes. Methods: This study included 2,607 patients from the Diabetes Prevention Program (DPP) and the Diabetes Prevention …

1723-P: Weight Reduction Mediated by Antiobesity Medications and the Risk of Obesity-Associated Cancer—A Meta-analysis of Randomized Controlled Trials

Chu Lin, Chengwen Li, Xiaoling Cai, LINONG JI

Introduction and Objective: Obesity is recognized as an independent risk factor for cancer. Whether the weight reduction mediated by anti-obesity medications (AOMs) contributes to the risk reduction in obesity-associated cancer remains to be unclear. Methods: PubMed, Embase, the Cochrane Center Register of …

745-P: Efficacy and Safety of RAY1225 Once Every Two Weeks in Chinese Adults with Obesity or Overweight (REBUILDING-1)

LINONG JI, Li Yan, Leili Gao, Min Xu et autres

Introduction and Objective: To investigate the efficacy, safety, and tolerability of RAY1225, a novel once every two weeks GLP-1 and GIP receptor dual agonist, in Chinese nondiabetic adults with overweight or obesity. Methods: This phase 2 double-blind, randomized, placebo-controlled trial included 2 …

856-P: Efficacy and Safety of Early Treatment Intensification Guided by Glycated Albumin in Newly Diagnosed Type 2 Diabetes—A Multicentre, Randomized Clinical Trial

Qian Ren, LINONG JI

Introduction and Objective: To testify that knowledge of glycated albumin and adjusting anti-diabetic regimens according to GA values result in improved glycemic control in newly diagnosed type 2 diabetes mellitus (T2DM). Methods: Multicentre, Randomized Clinical Trial. Setting: 7 hospitals in China between …

743-P: Efficacy and Safety of VCT220 in Chinese Adults with Overweight or Obesity

LINONG JI, Leili Gao, Chao Meng, Xianghua Zhang et autres

Introduction and Objective: To investigate the efficacy, safety, and tolerability of VCT220, a novel oral, small molecule once-daily glucagon-like peptide-1 receptor agonist, in Chinese nondiabetic adults with overweight or obesity. Methods: In this double-blind phase 2 randomized study, 250 Chinese adults with …

Region and Sex Disparities in the Burden of Early-Onset Type 2 Diabetes: Results from the Global Burden of Disease Study, 1990-2021

Jin Jiang, Qi Huang, Yingning Liu, Xueyao Han et autres

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Exon Sequencing of HNF1β in Chinese Patients with Early-Onset Diabetes

Siqian Gong, Hong Lian, Yating Li, Xiaoling Cai et autres

BACKGRUOUND: Maturity-onset diabetes of the young (MODY) due to variants of hepatocyte nuclear factor 1-beta (HNF1β) (MODY5) has not been well studied in the Chinese population. This study aimed to estimate its prevalence and evaluate the application of a clinical screening method …

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1167-P: Nonalcoholic Fatty Liver Disease, Metabolic Dysfunction Associated Fatty Liver Disease, and Associations with All-Cause and Cause-Specific Mortality

Qi Huang, Xiantong Zou, Xianghai Zhou, LINONG JI

The change in terminology from nonalcoholic fatty liver disease (NAFLD) to metabolic dysfunction-associated fatty liver disease (MAFLD) has raised heated discussion. Our study aims to investigate which has closer association with all-cause and cause-specific mortality in a population-based cohort. We investigated the …

275-OR: The Association between the Biological Disease-Modifying Antirheumatic Drugs and Incidence of Diabetes

CHU LIN, Hongyu Ji, Xiaoling Cai, Wenjia Yang et autres

Purpose: To evaluate the association between the biological disease-modifying anti-rheumatic drugs (bio-DMARDs) and the incidence of diabetes. Methods: Studies recording the incidence of new-onset diabetes in subjects treated with bio-DMARDs were included. Results: In total, 23 relevant studies were included. The pooled …

Effect of parity on autoimmune thyroid disease

Ning Yuan, Lin Li, Zhi Li, Jing Zhang et autres

The objective of this study was to evaluate parity as a risk factor for autoimmune thyroid disease (AITD) by comparing features of thyroid autoantibodies of pregnant women with different parities. This prospective cohort study included 477 women of first trimester of pregnancy …

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Chinese diabetes drug delivery guideline(2016)

LINONG JI, Xiaohui Guo

中国における潜在性自己免疫性糖尿病の発症率,免疫遺伝および臨床像(LADA China Study) : 全国的多施設共同クリニック対象横断試験

Zhiguang Zhou, Yufei Xiang, LINONG JI