Aliasgar Vohra

Melatonin improves neuro-behavioral perturbations in diet/photoperiod induced chronodisruption

Aliasgar Vohra, Rhydham Karnik, Hitarthi Vyas, Shruti Kulshrestha et autres

Abstract Endogenous circadian oscillators regulate learning, cognitive performance and memory are disrupted due to circadian shifts. High-fat-high-fructose (H) diet, photoperiodic shifts induced chronodisruption (CD) and a combination (HCD) causes neurobehavioral perturbations wherein; the merits of exogenous melatonin in alleviating the said behavioral …

in, us (code pays fourni par la source)

Circadian Clock protein Bmal1 drives inflammatory homing in monocytes via augmented Cxcr4 and Ccr2 axis

A Devkar, Rhydham Karnik, Helly Shah, Aliasgar Vohra et autres

in (code pays fourni par la source)

Pleiotropic properties and therapeutic potential of honey

Aliasgar Vohra, Rhydham Karnik, Shery Babu, Idris Mithaiwala et autres

us, in (code pays fourni par la source)

List of contributors

Md. Khokon Miah Akanda, Deepak Attri, Shery Babu, Ajay Balda et autres

Melatonin partially restores hepatic nocturnin oscillations in experimental models of MASLD

Shruti Kulshrestha, Rhydham Karnik, Aliasgar Vohra, Apeksha Joshi et autres

Melatonin, a pleiotropic neurohormone, is recognized for its hepatoprotective role in metabolic dysfunction-associated steatotic liver disease (MASLD) triggered by diet and/or chronodisruption. Nocturnin (Noct), a circadian clock output regulating hepatic lipid metabolism, has an unclear role in MASLD. This study explores circadian …

in (code pays fourni par la source)

Abstract 2356 Bmal1-Clock desynchrony impacts monocyte trafficking via activation of CXCR4/CCR2 chemotaxis pathway

Rhydham Karnik, Helly Shah, Aliasgar Vohra, Hitarthi Vyas et autres

Chemokine receptors (Cxcr4 and Ccr2) are implicated as modulators of monocyte trafficking and migration in mammals. Circadian oscillations of these chemokines have a regulatory role in patterning monocyte migration and inflammatory responses. Disruptions in circadian oscillations of monocytes is known to aggravate …

in (code pays fourni par la source)

Exogenous Melatonin Corrects Hepatic Nocturnin Levels in Experimentally Induced MASLD

Shruti Kulshrestha, Rhydham Karnik, Aliasgar Vohra, Apeksha Joshi et autres

Melatonin, a neurohormone, improves hepatic function in diet and/or chronodisruption in Metabolic dysfunction Associated with Steatotic Liver Disease (MASLD). Nocturnin (Noct), a circadian clock output gene, putatively regulates hepatic lipid metabolism but the underlying mechanisms related to its regulation remain largely unknown. …

in (code pays fourni par la source)

Diet/photoperiod mediated changes in cerebellar clock genes causes locomotor shifts and imperative changes in BDNF-TrkB pathway

Rhydham Karnik, Aliasgar Vohra, Mahamadtezib Khatri, Nilay Dalvi et autres

in, us (code pays fourni par la source)

Melatonin-mediated corrective changes in gut microbiota of experimentally chronodisrupted C57BL/6J mice

Aliasgar Vohra, Rhydham Karnik, Mansi Desai, Hitarthi Vyas et autres

Chronic consumption of a high-calorie diet coupled with an altered sleep-wake cycle causes disruption of circadian clock that can impact the gut microbiome leading to metabolic syndrome and associated diseases. Herein, we investigate the effects of a high fat high fructose diet …

in, us (code pays fourni par la source)

Abstract 1155 KH-type Splicing Regulatory Protein mediated upregulation of miR-34a negatively impacts lipid homeostasis in hepatocytes

Rhydham Karnik, Hitarthi Vyas, Aliasgar Vohra, Helly Shah et autres

MicroRNA-34a (miR-34a) is implicated as key modulator of lipid metabolism, homeostasis, beta-oxidation and peroxidation in hepatocytes. It is widely reported to be upregulated in several metabolic disorders viz. fatty liver, diabetes and atherosclerosis. Hence, it is imperative to answer questions pertaining to …

in (code pays fourni par la source)

Diet/Photoperiod Mediated Changes in Cerebellar Clock Genes Causes Locomotor Shifts and Imperative Changes in BDNF-TrkB Pathway

Rhydham Karnik, Aliasgar Vohra, Mahamadtezib Khatri, Nilay Dalvi et autres

in, us (code pays fourni par la source)

CCDC 1906438: Experimental Crystal Structure Determination

Irfan Shaikh, Aliasgar Vohra, Ranjitsinh V. Devkar, R.N. Jadeja

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …