Darlene A. Mitrano

Editorial: Decoding the neuroanatomy of addiction: insights into substance use disorders

Darlene A. Mitrano, Janet D. Robishaw

We are excited to share a series of articles centered on Decoding the Neuroanatomy of Addiction: Insights into Substance Use Disorders. Across six manuscripts, we present perspectives on different drugs of abuse, all with a neuroanatomical basis. These studies span the molecular …

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Localization and neurochemical identity of alpha1-adrenergic receptor-containing elements in the mouse locus coeruleus

Zachary N. M. Luyo, Abigail B. Lawrence, Theodore G. Stathopoulos, Darlene A. Mitrano

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Localization and Neurochemical Identity of Alpha1-Adrenergic Receptor-Containing Elements in the Mouse Locus Coeruleus

Zachary N. M. Luyo, Abigail B. Lawrence, Theodore G. Stathopoulos, Darlene A. Mitrano

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Olfactory dysfunction in the 3xTg-AD model of Alzheimer’s disease

Darlene A. Mitrano, Samuel Houle, Patrick Pearce, Ricardo M. Quintanilla et autres

Alzheimer's disease (AD) is an incurable neurodegenerative disease in which the risk of development increases with age. People with AD are plagued with deficits in their cognition, memory, and basic social skills. Many of these deficits are believed to be caused by …

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Two Scientists Share Nobel Prize for the First Time! A Case Study Developed for Exploring the History of Neuroanatomy.

Darlene A. Mitrano

century.

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Noradrenergic Transmission at Alpha1-Adrenergic Receptors in the Ventral Periaqueductal Gray Modulates Arousal

Kirsten A. Porter‐Stransky, Samuel W. Centanni, Saumya L. Karne, Lindsay M. Odil et autres

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Histochemical & Behavioral Analysis of the 3xTg‐AD Mouse Model of Alzheimer's Disease

Darlene A. Mitrano, Rachel Schendzielos, Emma E. Croushore, Benjamin C. Genovese et autres

Alzheimer's disease (AD) is an incurable neurodegenerative disease that affects about 11% of Americans age 65 and over and has very few FDA‐approved treatments. As the primary areas affected within the brain are the hippocampus and the cortex, the main reported symptoms …

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α1b-Adrenergic Receptor Localization and Relationship to the D1-Dopamine Receptor in the Rat Nucleus Accumbens

Darlene A. Mitrano, Kelsey Jackson, Samantha Finley-May, Allison Seeley

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D1-dopamine and α1-adrenergic receptors co-localize in dendrites of the rat prefrontal cortex

Darlene A. Mitrano, Jean‐François Paré, Yoland Smith, David Weinshenker

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Alpha-1 Adrenergic Receptors are Localized on Presynaptic Elements in the Nucleus Accumbens and Regulate Mesolimbic Dopamine Transmission

Darlene A. Mitrano, Jason P. Schroeder, Yoland Smith, James J. Cortright et autres

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FIRST: Fellowships in Research & Science Teaching: A differential approach to postdoctoral training

Darlene A. Mitrano, Arri Eisen, Douglas C. Eaton

As part of the IRACDA (Institutional Research and Career Development Awards, NIGMS) initiative, the FIRST program was developed in order to increase underrepresented minorities in postdoctoral fellowship positions in the life sciences, as well as to increase research oriented teaching at minority …

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Ultrastructural relationships between cortical, thalamic, and amygdala glutamatergic inputs and group I metabotropic glutamate receptors in the rat accumbens

Darlene A. Mitrano, Jean‐François Paré, Yoland Smith

Changes in glutamatergic transmission in the nucleus accumbens play a key role in mediating reward-related behaviors and addiction to psychostimulants. Glutamatergic inputs to the accumbens originate from multiple sources, including the prefrontal cortex, basolateral amygdala, and midline thalamus. The group I metabotropic …

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