Xianyuan Miao

Leveraging the Therapeutic Potential of Natural Peptide Panurgines: Hydrocarbon Stapling Strategy Enhances Their Efficacy Against Breast Cancer

Lei Chen, Xianyuan Miao, Qiongqiong Wang, Shuyue Fu et autres

The development of novel candidate molecules for breast cancer treatment holds significant clinical value. Panurgines (PNG), derived from the venom of the wild bee Panurgus calcaratus, are particularly noteworthy for their anti-breast cancer activity and antibacterial properties. However, linear peptides are often …

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Correction to: The radiomics nomogram predicts the prognosis of pancreatic cancer patients with hepatic metastasis after chemoimmunotherapy

Wenxin Lu, Guangyu Wu, Xianyuan Miao, Jingyu Ma et autres

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The radiomics nomogram predicts the prognosis of pancreatic cancer patients with hepatic metastasis after chemoimmunotherapy

Wenxin Lu, Guangyu Wu, Xianyuan Miao, Jingyu Ma et autres

OBJECTIVE: To construct a prognostic model based on MR features and clinical data to evaluate the progression free survival (PFS), overall survival (OS) and objective response rate (ORR) of pancreatic cancer patients with hepatic metastases who received chemoimmunotherapy. METHODS: 105 pancreatic cancer …

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The characteristics and novel clinical implications of CD4+CXCR5+Foxp3+ follicular regulatory T cells in breast cancer

Xianyuan Miao, Qiusheng Guo, Zhiwen Pan, Xiaohong Xu et autres

Background: Follicular regulatory T cells (Tfr) are a subset of regulatory T cells (Tregs) that suppress the humoral immune response in the germinal center. They are associated with increased rates of disease stabilization and decreased autoantibody levels in a variety of tumor …

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Abstract PS6-51: Identification of a low-risk luminal breast cancer cohort that may not benefit from multi-gene testing

Lei Lei, Han-Ching Chan, Tzu‐Pin Lu, Xianyuan Miao et autres

Abstract Purpose: Dutch clinical risk criteria (low-risk definition: age > 35 years and (grade 1 with tumor ≤3cm, grade 2 with tumor ≤2cm, or grade 3 with tumor ≤1cm) have been used to stratify the benefit of MammaPrint and Oncotype DX for …

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Prognostic significance of mammary Paget’s disease in Chinese women: a 10 year, population-based, matched cohort study

Huanhuan Zhou, Kongbeng Lu, Lei Zheng, Liwei Guo et autres

Purpose: To explore the prognostic significance of mammary Paget’s disease (PD) in breast cancer (BC) patients and to investigate the association between clinical manifestation and outcome in invasive ductal carcinoma patients with PD (PD-IDC). Patients and methods: Eighty-five patients diagnosed with mammary …

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