Thaisa M. Cantu-Jungles

Fiber and Anthocyanin Mixtures in Ameliorating Ulcerative Colitis-Associated Microbial Dysbiosis

Paola Andino, Sarah Quino, Ann Klipsch, Thaisa M. Cantu-Jungles et autres

Objectives: Patients with ulcerative colitis (UC) often restrict fiber intake due to poor tolerance. Designed prebiotic fiber mixtures have been shown to improve tolerance and enhance short-chain fatty acid (SCFA) production. Complexation of fiber with anthocyanins increases polyphenol stability and colonic delivery. …

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Prebiotic intervention changes host and microbe proteomes in plasma extracellular vesicles of Parkinson’s disease

Deepak Sharma, Robin M. Voigt, Deborah A Hall, Thaisa M. Cantu-Jungles et autres

We hypothesize that intestinal microbiome dysbiosis may contribute to Parkinson’s disease (PD) pathogenesis. Our prior proof-of-concept clinical trial demonstrated that a precision prebiotic intervention improved microbiota dysbiosis and alleviated gastrointestinal and motor symptoms in PD patients. Building on this, we analyzed plasma …

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Influence of toasted sorghum flour phenolic compounds and dietary fibers on gut microbiota and short-chain fatty acid production

Laise Trindade Paes, Thaisa M. Cantu-Jungles, Mirian Aparecida de Campos Costa, Clay Swackhamer et autres

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New Insights into Synergistic Boosts in SCFA Production Across Health Conditions Induced by a Fiber Mixture

Gabriel S. Galeano-Garcia, Tingting Chen, Phillip A. Engen, Ali Keshavarzian et autres

Background/Objectives: Short-chain fatty acids (SCFAs) produced by gut microbiota from dietary fiber fermentation play crucial roles in health and disease. While most research focuses on individual fibers, this study investigated whether a fiber mixture could synergistically increase SCFAs, exceeding the expected average …

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New high-specificity fibers with strong and consistent responses across individuals

Mirian Aparecida de Campos Costa, Dirce L. Komura, Elaine R. Carbonero, Grethel Teresa Choque Delgado et autres

, respectively), with strong and consistent responses across individuals, features characteristic of high-specificity fibers. In contrast, Fructooligosaccharides and Xylooligosaccharides produced more variable, and less intense responses. Our findings support Acacia, Fucogalactan, Guar, and Locust as high-specificity fibers that induce consistent, taxon-targeted shifts …

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Shared Dynamics of the Colonic Microbiome Make Responses to Fiber Interventions Unexpectedly Consistent Among Individuals

Clay Swackhamer, Thaisa M. Cantu-Jungles, Bruce R. Hamaker

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Designed Prebiotic Fiber Mixtures for Superior Gut Microbiota and Whole-Body Health

Thaisa M. Cantu-Jungles, Frank Schuren, Bruce R. Hamaker

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1103: DESIGNED PREBIOTIC RESTRUCTURES THE PLASMA EXTRACELLULAR VESICLES PROTEOME AND MICROBIOME IN PARKINSON’S DISEASE

Deepak Sharma, Deborah A. Hall, Robin M. Voigt, Thaisa M. Cantu-Jungles et autres

Dietary fibre responses in microbiota reveal opportunity for disease-specific prebiotic approaches

Tingting Chen, Thaisa M. Cantu-Jungles, Bin Zhang, Ting Yao et autres

Prebiotics or fermentable dietary fibres are known for their potential to shape the gut microbial community and could be used as a tool in treating gut dysbiotic states found in a wide range of diseases. However, it remains unclear whether the microbiota …

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Use of a Novel Passive E-Nose to Monitor Fermentable Prebiotic Fiber Consumption

Lawrence R. Kosinski, Phillip A. Engen, Barbara Swanson, Michelle Villanueva et autres

We developed a home-based electronic nose (E-Nose) to passively monitor volatile organic compounds (VOCs) emitted following bowel movements and assessed its validity by correlating the output with prebiotic fiber intake. Healthy, non-overweight participants followed a three-week protocol which included the following: (1) …

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Prebiotics as an adjunct therapy for posttraumatic stress disorder: a pilot randomized controlled trial

Robin M. Voigt, Phillip A. Engen, Michelle Villanueva, Simona A. Bambi et autres

Introduction: Posttraumatic stress disorder (PTSD) is a debilitating disorder characterized by intrusive memories, avoidance, negative thoughts and moods, and heightened arousal. Many patients also report gastrointestinal symptoms. Cognitive behavioral therapy (CBT) is an evidence-based treatment approach for PTSD that successfully reduces symptoms. …

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INFLUENCE OF TOASTED SORGHUM FLOUR PHENOLIC COMPOUNDS AND DIETARY FIBERS ON GUT MICROBIOTA AND SHORT-CHAIN FATTY ACID PRODUCTION

Laise Trindade Paes, Thaisa M. Cantu-Jungles, Mirian Aparecida de Campos Costa, Clay Swackhamer et autres

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