Annick Chauty

Changes in Inflammatory Markers in Patients Treated for Buruli Ulcer and Their Ability to Predict Paradoxical Reactions

Michael Phelippeau, Estelle Marion, Marie Robbe-Saule, Line Ganlanon et autres

Mycobacterium ulcerans causes Buruli ulcer, the third most frequent mycobacterial disease after tuberculosis and leprosy. Transient clinical deteriorations, known as paradoxical reactions (PRs), occur in some patients during or after antibiotic treatment. We investigated the clinical and biological features of PRs in …

vn, fr, Maroc, Bénin (code pays fourni par la source)

Genome-wide association study of Buruli ulcer in rural Benin highlights role of two LncRNAs and the autophagy pathway

Jérémy Manry, Quentin B. Vincent, Christian Roch Johnson, Maya Chrabieh et autres

Abstract Buruli ulcer, caused by Mycobacterium ulcerans and characterized by devastating necrotizing skin lesions, is the third mycobacterial disease worldwide. The role of host genetics in susceptibility to Buruli ulcer has long been suggested. We conduct the first genome-wide association study of …

fr, Bénin, Sénégal, us (code pays fourni par la source)

Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial

Richard Odame Phillips, Jérome Robert, Kabiru Mohamed Abass, William A. Thompson et autres

BACKGROUND: Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans infection that damages the skin and subcutis. It is most prevalent in western and central Africa and Australia. Standard antimicrobial treatment with oral rifampicin 10 mg/kg plus intramuscular streptomycin 15 …

Ghana, fr, Tunisie, Bénin, gb, us, Congo, nl, ch (code pays fourni par la source)

Genome-wide association study of Buruli ulcer in rural Benin

Jérémy Manry, Quentin B. Vincent, Maya Chrabieh, Lazaro Lorenzo et autres

Abstract Buruli ulcer, caused by Mycobacterium ulcerans , is the third mycobacterial disease worldwide characterized by devastating necrotizing skin lesions. The role of host genetics in susceptibility to Buruli ulcer has long been suggested. We conduct the first genome-wide association study of …

fr, Bénin, us (code pays fourni par la source)

Randomised Trial to Compare Clarithromycin (Extended Release)-Rifampicin and Streptomycin-Rifampicin for Early, Limited Lesions of M. Ulcerans Infection

Richard Odame Phillips, Jérome Robert, Kabiru Mohamed Abass, William A. Thompson et autres

Ghana, fr, in, us, ch, gb, ca, Bénin, pk, nl (code pays fourni par la source)

Occurrence and persistence of biofilms on cared chronic wounds: A large multicentric clinical study

Isabelle Fromantin, Damien Seyer, Florence Rollot, Sylvie Meaume et autres

fr (code pays fourni par la source)

Microdeletion on chromosome 8p23.1 in a familial form of severe Buruli ulcer

Quentin B. Vincent, Aziz Belkadi, Cindy Fayard, Estelle Marion et autres

Buruli ulcer (BU), the third most frequent mycobacteriosis worldwide, is a neglected tropical disease caused by Mycobacterium ulcerans. We report the clinical description and extensive genetic analysis of a consanguineous family from Benin comprising two cases of unusually severe non-ulcerative BU. The …

fr, Bénin, us (code pays fourni par la source)

Draft Genome Sequence of Mycobacterium ulcerans S4018 Isolated from a Patient with an Active Buruli Ulcer in Benin, Africa

Stanimir Kambarev, Stéphane Corvec, Annick Chauty, Estelle Marion et autres

ABSTRACT Currently, there are only two publicly available genomes of Mycobacterium ulcerans —the causative agent of the neglected, but devastating, tropical disease Buruli ulcer. Here, we report the draft genome sequence of isolate S4018, recovered from an active cutaneous lesion of a …

fr (code pays fourni par la source)

Cutaneous basidiobolomycosis: Seven cases in southern Benin

F. Atadokpèdé, Jacques Gnossike, Hector Guy Adégbidi, Bérénice Dégboé et autres

Bénin, fr, Sénégal (code pays fourni par la source)

Multiple introductions and recent spread of the emerging human pathogen Mycobacterium ulcerans across Africa

Koen Vandelannoote, Conor Joseph Meehan, Miriam Eddyani, Dissou Affolabi et autres

Buruli ulcer (BU) is an insidious neglected tropical disease. Cases are reported around the world but the rural regions of West and Central Africa are most affected. How BU is transmitted and spreads has remained a mystery, even though the causative agent, …

be, Bénin, République démocratique du Congo, Cameroun, au, fr (code pays fourni par la source)

CO 12 : Basidiobolomycoses au sud du Bénin : aspects épidémiologiques, cliniques et thérapeutiques de sept cas

F. Atadokpèdé, Christiane Koudoukpo, Hector Guy Adégbidi, Bérénice Dégboé et autres

Clinical Features of Spontaneous Partial Healing During Mycobacterium ulcerans Infection

Estelle Marion, Annick Chauty, Marie Kempf, Yannick Le Corre et autres

Background. Buruli ulcer, caused by Mycobacterium ulcerans, is a necrotizing skin disease leading to extensive cutaneous and subcutaneous destruction and functional limitations. Spontaneous healing in the absence of medical treatment occurs in rare cases, but this has not been well described in …

fr, Mali, ch (code pays fourni par la source)