James T. Paul

FEASIBILITY AND SAFETY OF ORGAN PRESERVING THERAPY FOR EARLY STAGE OR INDUCED EARLY-STAGE ESOPHAGEAL CANCER USING ENDOSCOPIC SUBMUCOSAL DISSECTION (ESD) AND ADJUVANT IMMUNORADIOTHERPY WITH DURVALUMAB (OPERA-RADIO): A PHASE 1 CLINICAL TRIAL

Julian S. Kim, Shantanu Otto Banerji, James T. Paul, Rebekah Rittberg et autres

Report from the 25th Annual Western Canadian Gastrointestinal Cancer Consensus Conference on Gastric and Gastroesophageal Cancers, Winnipeg, Manitoba, 26–27 October 2023

Ralph P. W. Wong, Brady J. Anderson, Bashir Bashir, Justin Bateman et autres

The 25th Annual Western Canadian Gastrointestinal Cancer Consensus Conference (WCGCCC) was held in Winnipeg, Manitoba, on 26-27 October 2023. The WCGCCC is an interactive multidisciplinary conference that was attended by healthcare professionals from across Western Canada (British Columbia, Alberta, and Manitoba) who …

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Correction: Gill et al. Report from the 24th Annual Western Canadian Gastrointestinal Cancer Consensus Conference on Colorectal Cancer, Richmond, British Columbia, 28–29, October 2022. Curr. Oncol. 2023, 30, 7964–7983

Sharlene Gill, Shahid Ahmed, Brady J. Anderson, Scott R. Berry et autres

Karen Mulder was not included as an author in the original publication [...].

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Real-world predictors of survival in patients with limited-stage small-cell lung cancer in Manitoba, Canada

David E. Dawe, Rebekah Rittberg, Iqra A. Syed, Mary Kate Shanahan et autres

Background: Although therapy for limited-stage small-cell lung cancer (LS-SCLC) is administered with curative intent, most patients relapse and eventually die of recurrent disease. Chemotherapy (CT) with concurrent radiotherapy (RT) remains the standard of care for LS-SCLC; however, this could evolve in the …

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Real-world predictors of survival in patients with extensive-stage small-cell lung cancer in Manitoba, Canada: a retrospective cohort study

David E. Dawe, Rebekah Rittberg, Iqra A. Syed, Mary Kate Shanahan et autres

Background: Extensive-stage small-cell lung cancer (ES-SCLC) is an incurable cancer with poor prognosis in which characteristics predictive of long-term survival are debated. The utility of agents such as immune checkpoint inhibitors highlights the importance of identifying key characteristics and treatment strategies that …

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Report from the 24th Annual Western Canadian Gastrointestinal Cancer Consensus Conference on Colorectal Cancer, Richmond, British Columbia, 28–29, October 2022

Sharlene Gill, Shahid Ahmed, Brady J. Anderson, Scott R. Berry et autres

The 24th annual Western Canadian Gastrointestinal Cancer Consensus Conference (WCGCCC) was held in Richmond, British Columbia, on 28-29 October 2022. The WCGCCC is an interactive multidisciplinary conference attended by healthcare professionals from across Western Canada (British Columbia, Alberta, Saskatchewan, and Manitoba) who …

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1547P Predictors of short-, medium-, and long-term survival with limited stage small cell lung cancer in the real-world

David E. Dawe, Rebekah Rittberg, Oliver Bucher, K. Galloway et autres

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Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

Philip Law, Maria N Timofeeva, Ceres Fernández–Rozadilla, Peter Broderick et autres

A single institution retrospective review of efficacy, toxicity, and symptom burden in patients (pts) with pancreatic cancer (PaC) receiving FOLFIRINOX chemotherapy.

James T. Paul, Pascal J. Lambert, Joel Roger Gingerich, Piotr Czaykowski et autres

e15221 Background: PaC is associated with a poor prognosis. FOLFIRINOX chemotherapy improves overall survival (OS) in this disease, but may be associated with poor tolerance, and toxicity. We sought to evaluate efficacy, toxicity and symptom burden in a consecutive series of PaC …

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Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1–BCR-ABL–JAK2 Complex

Min Chen, Paolo Gallipoli, Donna DeGeer, Ivan Sloma et autres

BACKGROUND: Imatinib mesylate (IM) induces clinical remission of chronic myeloid leukemia (CML). The Abelson helper integration site 1 (AHI-1) oncoprotein interacts with BCR-ABL and Janus kinase 2 (JAK2) to mediate IM response of primitive CML cells, but the effect of the interaction …

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Adverse Events Associated with Bone Marrow Biopsy In A Resident Training Program; First Do No Harm

James T. Paul, Emily K. Rimmer, Carmen M. Cabrera Morales, Graham H. Bay et autres

Abstract Abstract 4775 BACKGROUND: Bone marrow aspirates and biopsies are commonly performed to evaluate a variety of hematological abnormalities. Generally, it is regarded as a safe procedure; however, the complication rate is uncertain. Much of the data surrounding bone marrow complications derives …

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Cyclin D expression in chronic lymphocytic leukemia

James T. Paul, Elizabeth S. Henson, Sabine Mai, J. Frederic Mushinski et autres

Although the majority of circulating leukemic cells in chronic lymphocytic leukemia (CLL) are in G0/early G1, recent studies have shown that these cells have undergone multiple cell divisions. In this study, we have determined whether there are abnormalities in cell cycle control …

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