Kuikui Hu

Mechanical force promotes tissue and molecular changes in adipose tissue regeneration post-transplantation

Ye Yuan, Jian Ma, B. Guo, X. Li et autres

Introduction: Fat grafting often yields inconsistent and suboptimal results, necessitating improved fat processing techniques. A stromal vascular fraction (SVF) gel created using mechanical emulsification demonstrates superior retention rates to conventional Coleman fat grafts. Methods: This study investigated the mechanisms at play by …

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Dermatoscope for the diagnosis of erythema with purpura induced by lidocaine/prilocaine cream: A case report

Lin Xiu, Jindou Jiang, Xue-Zhen Guo, Kuikui Hu

BACKGROUND: Lidocaine/prilocaine (EMLA) cream is a local anesthetic that is applied to the skin or mucosa during painful therapeutic procedures with few reported side effects. CASE SUMMARY: Here, we report the use of dermatoscopy to identify a case of erythema with purpura, …

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By Fibrotic Regulation, Long Noncoding RNA-ATB Promotes the Occurrence and Development of Scleroderma

Lin Xiu, Jindou Jiang, Meijun Tan, Kuikui Hu et autres

We used intervention means to investigate the mechanism of LncRNA-ATB involved in the development and progression of Scleroderma by examining the expression differences of LncRNA-ATB between lesional skin of Scleroderma patients and normal skin using a cellular model. Lesional skin and normal …

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Phenotypic and Cellular Characteristics of a Stromal Vascular Fraction/Extracellular Matrix Gel Prepared Using Mechanical Shear Force on Human Fat

Ye Yuan, Jingjiang Zou, Meijun Tan, Kuikui Hu et autres

The retention of fat-derived grafts remains a challenge for regenerative medicine. Fat aspirates from patients undergoing liposuction were prepared into standard Coleman fat grafts or further isolated using mechanical shear force to prepare a stromal vascular fraction (SVF)/extracellular matrix (ECM) gel. The …

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Study on the anti-inflammatory and lipid-lowering activities of novel chimeric peptide

Cong Liu, Meijun Tan, Kaixiang Cao, Jingwei Yan et autres

Acne was treated by combining the N-terminal of HPA3NT3 (where Lys in position 13 was replaced by Asn) and the C-terminal antibacterial peptide HAG of GLP-1 (32–36) amide pentapeptide after amino replacement. The minimal inhibitory concentration (MIC) was measured using the broth …

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Tear trough deformity: different types of anatomy and treatment options

Jindou Jiang, Xuekun Wang, Rongrong Chen, Xueying Xia et autres

AIM: To explore the efficacy of tear trough deformity treatment with the use of hyaluronic acid gel or autologous fat for soft tissue augmentation and fat repositioning via arcus marginalis release. MATERIAL AND METHODS: Seventy-eight patients with the tear trough were divided …

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An Experimental Study on Preparing Trestle of Tissue Engineering for Skin by Collagen

Kuikui Hu

Objective To build the trestle of tissue engineering for skin with collagen.Methods The collagen was obtained from the tendon of mouse tail.Its complicated manufacture involved precipitation of chondroitin-6-sulfate and collagen which were then freeze dried,dehydrathermal,cross-linked by gluteraldehyde and carefully washed.These collagen membranes …