Angela McLigeyo

Clinical Presentation of Chronic Myeloid Leukaemia and Its Correlation with Haematological Parameters in Kenya

Nicholas Anthony Othieno-Abinya, Joseph David Macharia Maina, Angela McLigeyo, Andrew Oluoch Odhiambo et autres

Background: Chronic myeloid leukaemia (CML) is commonly asymptomatic and is discovered incidentally in up to about 50% of patients in chronic phase, due to abnormally high white blood cell (WBC) counts. Commonest symptoms include fatigue and abdominal pain/discomfort, while some patients present …

Kenya, it (code pays fourni par la source)

Characteristics and mortality risk among esophageal cancer patients with varied HIV status seeking care in western Kenya: A 10-year analysis.

Dorothy I. Mangale, Harriet Fridah Adhiambo, Phiona Awuor Adagi, Everline Nyandieka et autres

e16090 Background: Esophageal cancer (EC) is among the top five prevalent cancers in Africa, including at Jaramogi Oginga Odinga Training and Referral Hospital (JOOTRH). EC is associated with poor prognosis and data to inform improvements are limited. Furthermore, the characteristics and impact …

us, Kenya (code pays fourni par la source)

Survival disparities between patients with breast cancer with and without HIV at Jaramogi Oginga Odinga Teaching and Referral Hospital (JOOTRH).

Harriet Fridah Adhiambo, Thomas Odeny, Dorothy I. Mangale, Phiona Awuor Adagi et autres

1622 Background: Breast cancer and HIV/AIDS pose significant public health challenges. Women living with HIV face higher mortality rates when diagnosed with breast cancer than HIV-negative women. Although advancements in treatment have improved survival outcomes, limited evidence exists on the impact of …

Kenya, us (code pays fourni par la source)

Survival and predictors of mortality among patients with virus-associated cancers in a high HIV-prevalence region in Kenya: A 10-year retrospective study.

Dorothy I. Mangale, Everline Nyandieka, Phiona Awuor Adagi, Betsy Abente et autres

e22529 Background: Virus-associated cancers cause significant mortality in Africa. Understanding risk factors for mortality is crucial for effective prevention and treatment. We analyzed demographic and clinical characteristics of people with virus-associated cancers in Kisumu County, western Kenya – a region with a …

us, Kenya (code pays fourni par la source)

Decentralizing cancer care in sub-Saharan Africa through an integrated regional cancer centre model: The case of Kenya

Mary Flaviane Nyangasi, Angela McLigeyo, David Kariuki, Siwillis Elizabeth Mithe et autres

For 50 years, comprehensive cancer treatment services were provided at one public hospital and a few private facilities in the capital city. In 2019, the services were decentralized to new national and regional centers to increase service accessibility using an integration model. …

Kenya (code pays fourni par la source)

Report of a chronic myeloid leukemia registry in a low-and middle-income setting.

Nicolas Anthony Othieno-Abinya, Walter Otieno Mwanda, Miriam Claire Mutebi, Mary Flaviane Nyangasi et autres

7054 Background: Treatment of chronic myeloid leukaemia (CML) in Kenya has been supported since the year 2002 by a collaboration between the Max Foundation and Novartis Pharmaceuticals in the Glivec International Patient Assistance Program (GIPAP). In November 2020 this was transitioned to …

Kenya (code pays fourni par la source)

Treatment failure with first line imatinib for patients with chronic myeloid leukaemia in Kenya vs high-income countries.

Angela McLigeyo, Nicolas Abinya, Sitna Ali Mwanzi, Peter Omondi Oyiro et autres

e19068 Background: Chronic Myeloid Leukemia (CML) occurs in all age groups but predominantly in adults. The disease pathogenesis is typified by the presence of BCR-ABL fusion protein coded for by BCR-ABL gene, a product of reciprocal translocation between the long arms of …

Kenya (code pays fourni par la source)

Efficacy and safety of ponatinib in management of chronic myeloid leukaemia: Experience from Kenya.

Nicolas Anthony Othieno-Abinya, Angela McLigeyo, Peter Omondi Oyiro, Andrew Oluoch Odhiambo et autres

e19067 Background: BCR-ABL tyrosine kinase inhibitors imatinib, nilotinib, bosutinib, and dasatinib, are used upfront in the management of chronic myeloid leukaemia (CML). In terms of resistance, ponatinib is the most potent tyrosine kinase inhibitor used in CML. It is however not used …

Kenya (code pays fourni par la source)

Access to essential cancer medicines for children: a comparative mixed-methods analysis of availability, price, and health-system determinants in east Africa

Kadia Petricca, Joyce Kambugu, Jessie Nyokabi Githanga, William Macharia et autres

ca, Ouganda, Kenya, Rwanda, Tanzanie, us (code pays fourni par la source)

Survival probability and factors associated with time to loss to follow-up and mortality among patients on antiretroviral treatment in central Kenya

Paul Wekesa, Angela McLigeyo, Kevin Omondi Owuor, Jonathan Mwangi et autres

BACKGROUND: Retention of patients who are receiving antiretroviral therapy (ART) remains a challenge especially in the setting of rapid expansion of HIV services. Retention in care remains vital to the HIV care continuum, and has been associated with viral suppression and improved …

Kenya (code pays fourni par la source)

Characteristics and Treatment Response of Patients with HIV Associated Kaposi’s Sarcoma in Central Kenya

Angela McLigeyo, Kevin Omondi Owuor, Evelyne Ng'ang'a, Jonathan Mwangi et autres

Introduction: Kaposi's sarcoma (KS) is the most common HIV-associated malignancy in Sub Saharan Africa. In 2018, it was the 7th most common cancer and the 10th most common cause of cancer death in Kenya. This study aimed to describe the baseline and …

Kenya (code pays fourni par la source)

Characteristics and Treatment Response of Patients with HIV Associated Kaposi’s Sarcoma in Central Kenya

Angela McLigeyo, Kevin Omondi Owuor, Evelyne Ng'ang'a, Jonathan Mwangi et autres

Angela McLigeyo,1 Kevin Owuor,1 Evelyne Ng’ang’a,1 Jonathan Mwangi,2 Paul Wekesa1 1Center for Health Solutions - Kenya, Nairobi, Kenya; 2Division of Global HIV & TB, Centers for Disease Control and Prevention (CDC), Nairobi, KenyaCorrespondence: Paul Wekesa, Centre for Health Solutions – Kenya, CVS …