Accès ouvert
2025
article
OpenAlex
Eva Dohle, Marlene Quernheim, Robert Alexander Sader, Shahram Ghanaati
Periodontitis is a prevalent condition that leads to the destruction of periodontal tissue, making the regeneration of the periodontium a key focus in dental research. In this context, periodontal ligament cells (PDLCs) are particularly interesting due to their stem cell-like properties, including …
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Accès ouvert
2025
article
OpenAlex
Emilio Alfredo Cafferata, Aušra Ramanauskaitė, Puria Parvini, Clemens Raabe et autres
AIM: To evaluate the T regulatory lymphocyte (Treg) profile and its potential contribution to peri-implant tissue destruction during peri-implantitis (PI). METHODS: PI granulation tissue and crevicular fluid collected during PI surgical (PI group, n = 23) and explantation (PI-X group, n = …
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Accès ouvert
2025
article
OpenAlex
Eva Dohle, Büşra Yaprak Bayrak, Anja Heselich, Birgit Schäfer et autres
Background/Objectives: The body’s reaction after the implantation of a biomaterial is a non-specific inflammatory response that is mainly initiated via the recruitment of polymorphonuclear cells (PMNs) to the implant site secreting cytokines and growth factors, followed by activation of monocytes/macrophages, finally leading …
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Accès ouvert
2025
article
OpenAlex
Shahram Ghanaati, Eva Dohle, Fabian Schick, Johann Lechner
Background/Objectives: Immune cells are integral to bone homeostasis, including the repair and remodeling of bone tissue. Chronic dysregulation within this osteoimmune network can lead to bone marrow defects of the jaw (BMDJ), particularly fatty degenerative osteonecrosis of the jaw (FDOJ). These localized …
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Accès ouvert
2025
erratum
OpenAlex
Emilio Alfredo Cafferata, Aušra Ramanauskaitė, Astrid Cuypers, Karina Obreja et autres
Erratum for: Experimental peri-implantitis induces neuroinflammation: An exploratory study in rats. Cafferata EA, Ramanauskaite A, Cuypers A, Obreja K, Dohle E, Ghanaati S, Schwarz F. BMC Oral Health. 2024 Oct 18;24(1):1238. doi: 10.1186/s12903-024-04995-z.
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Accès ouvert
2025
article
OpenAlex
Anja Heselich, Eva Dohle, Mihaela Felicia Băciuț, Cristian Mihail Dinu et autres
Childhood trauma defects in the head and neck area are challenging in many aspects for patients and surgeons. One major issue is the still incomplete growth. Bone defect fixation measures have to consider biomechanical forces due to the bone growth from both …
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Accès ouvert
2024
article
OpenAlex
Eva Dohle, Robert Alexander Sader, Shahram Ghanaati
Nonmelanoma skin cancer (NMSC) presents a significant challenge to global healthcare due to its rising incidence, prompting the search for innovative treatments to overcome the limitations of current therapies. Our study aims to explore the potential effects of the liquid blood concentrate …
de
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Accès ouvert
2024
article
OpenAlex
Emilio Alfredo Cafferata, Aušra Ramanauskaitė, Astrid Cuypers, Karina Obreja et autres
Abstract Purpose Cumulating evidence supports the close association between periodontal diseases, neuroinflammation and neurodegenerative pathologies, except for peri-implantitis (PI). Thus, this study explored the association between experimental PI and neuropathological changes in the rat brain. Materials and methods After bilateral first molars …
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Accès ouvert
2024
article
OpenAlex
Carlos Fernando Mourão, Eva Dohle, Büşra Yaprak Bayrak, A.-L. Winter et autres
Platelet-rich fibrin (PRF) is a widely used autologous blood concentrate in regenerative medicine. This study aimed to characterize the cellular composition and distribution of different PRF matrices generated by high (710 g) and low (44 g) relative centrifugal forces (RCFs) and to …
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Accès ouvert
2024
article
OpenAlex
Eva Dohle, Kamelia Parkhoo, Francesco Bennardo, Lena Schmeinck et autres
The understanding that tumor cells might evade immunity through various mutations and the potential of an augmented immune system to eliminate abnormal cells led to the idea of utilizing platelet-rich fibrin (PRF), a blood concentrate containing the body's immune elements as an …
de, it
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Accès ouvert
2024
article
OpenAlex
Sarah Al‐Maawi, Eva Dohle, Robert Alexander Sader, Shahram Ghanaati
Platelet-rich fibrin (PRF) has assumed an important role in supporting tissue regeneration in different fields. To date, the standard protocol for liquid PRF requires at least 10 mL of peripheral blood. The present study aimed to analyze the composition, growth factor release, …
de
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Accès ouvert
2024
article
OpenAlex
Eva Dohle, Lena Schmeinck, Kamelia Parkhoo, Robert Alexander Sader et autres
Blood concentrates like platelet rich fibrin (PRF) have been established as a potential autologous source of cells and growth factors with regenerative properties in the field of dentistry and regenerative medicine.To further analyze the effect of PRF on bone tissue regeneration, this …
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