Jiahao Yin

Diffusion reconstruction with validity masks and measurement consistency for low-frame structured illumination microscopy

Junli Wu, Song Dawei, Haoran Zhang, Siying Huang et autres

Reducing the raw-frame budget of structured illumination microscopy (SIM) lowers exposure burden but weakens orientation–phase diversity and increases sensitivity to noise and model mismatch. We present acquisition-aware physics-guided diffusion for SIM (APD-SIM), which combines a protocol-specific conditional diffusion prior with validity-masked Poisson–Gaussian …

cn (code pays fourni par la source)

Learnable foveated sampling and dual-prior reconstruction for single-pixel imaging

Xin Huang, Qiurong Yan, Dawei Song, Z. Xiong et autres

Single-pixel imaging (SPI) is a low-cost, high-sensitivity compressed sensing technique with broad application prospects. Most existing deep learning-based SPI reconstruction methods adopt a uniform sampling strategy. They fail to fully exploit the flexibly programmable nature of sampling patterns in SPI. Inspired by …

Figure S1 from cGAS mRNA–Based Immune Agonist Promotes Vaccine Responses and Antitumor Immunity

Yali Qu, Zhibin Li, Jiahao Yin, He Huang et autres

Characterization of the LNPs

Figure S12 from cGAS mRNA–Based Immune Agonist Promotes Vaccine Responses and Antitumor Immunity

Yali Qu, Zhibin Li, Jiahao Yin, He Huang et autres

cGAS mRNA-LNP induces immune activation in tumor-infiltrating lymphocytes

Figure S6 from cGAS mRNA–Based Immune Agonist Promotes Vaccine Responses and Antitumor Immunity

Yali Qu, Zhibin Li, Jiahao Yin, He Huang et autres

Representative gating strategy for splenic cells in the immunization model

Figure S10 from cGAS mRNA–Based Immune Agonist Promotes Vaccine Responses and Antitumor Immunity

Yali Qu, Zhibin Li, Jiahao Yin, He Huang et autres

hcGASK187N_L195R mRNA-LNP restrict tumor progression

Figure S9 from cGAS mRNA–Based Immune Agonist Promotes Vaccine Responses and Antitumor Immunity

Yali Qu, Zhibin Li, Jiahao Yin, He Huang et autres

cGAS mRNA-LNP drives a robust vaccine response with minimal toxicity

Figure S5 from cGAS mRNA–Based Immune Agonist Promotes Vaccine Responses and Antitumor Immunity

Yali Qu, Zhibin Li, Jiahao Yin, He Huang et autres

Delivery efficiency of LNPs in multiple organs

Figure S3 from cGAS mRNA–Based Immune Agonist Promotes Vaccine Responses and Antitumor Immunity

Yali Qu, Zhibin Li, Jiahao Yin, He Huang et autres

cGAS mRNA-LNPs activate APCs in vitro and the cytotoxicity of LNPs in cultured cells

Figure S13 from cGAS mRNA–Based Immune Agonist Promotes Vaccine Responses and Antitumor Immunity

Yali Qu, Zhibin Li, Jiahao Yin, He Huang et autres

cGAS mRNA-LNP activated splenic immune cells in the tumor model

Figure S4 from cGAS mRNA–Based Immune Agonist Promotes Vaccine Responses and Antitumor Immunity

Yali Qu, Zhibin Li, Jiahao Yin, He Huang et autres

cGAS mRNA-LNPs induce innate immune activation in human PBMC in vitro

Figure S14 from cGAS mRNA–Based Immune Agonist Promotes Vaccine Responses and Antitumor Immunity

Yali Qu, Zhibin Li, Jiahao Yin, He Huang et autres

Graphic abstract of the research