Yaiza Tobajas

Peripheral blood mononuclear cells capture alterations in bone and immunometabolic-related metabolism in postmenopausal rats

Julio Baudin, Hong Qiong Yang, Juan María Alcaide‐Hidalgo, Yaiza Tobajas et autres

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Bifidobacterium longum CBi0703 lysate modulates oxidative stress induced apoptosis and cartilage related gene expression in SW1353 chondrocytes: in vitro insights into the gut joint axis in Osteoarthritis

Anna Mas-Capdevila, Lydia Carrera-Marcolin, Jordina Balaguer-Trias, Cristina Domenech-Coca et autres

Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage degradation, inflammation, and impaired joint function. This in vitro study evaluates the effects of Bifidobacterium longum CBi0703 lysate, alone and in combination with clinically used OA nutraceuticals, on viability, apoptosis and cartilage …

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Comparative study of the effects of different iron sources on bioavailability and gastrointestinal tolerability in iron-deficient rats

Roger Mariné-Casadó, Yaiza Tobajas, Anna Antolín, Teresa Negra et autres

Iron deficiency anaemia is a global health issue affecting millions of people. Though effective, conventional iron sources used for supplementation often cause gastrointestinal side effects. This preclinical study evaluated the efficacy and tolerability of three iron supplements—ferrous bisglycinate, LIPOFER™ microcapsules (Def-LFe1), and …

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Sustainable Polyphenol-Rich Extracts from Agricultural By-Products: Infectivity Inhibition Potential for Human Coronavirus 229E

Joan Teichenne-Jané, Yaiza Tobajas, Kevin R Leonard, Job Tchoumtchoua et autres

Polyphenol-rich extracts derived from agricultural by-products exhibit promising antiviral properties. This study evaluated the antiviral potential of extracts from red onion peels, vineyard prunings, olive prunings and chicory leaves against human coronavirus HuCoV-229E. Subcritical water extraction and resin adsorption techniques were applied …

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Exploring the Relationship between Diamine Oxidase and Psychotropic Medications in Fibromyalgia Treatment, Finding No Reduction in Diamine Oxidase Levels and Activity except with Citalopram

Yaiza Tobajas, Marc Alemany-Fornés, Iris Samarra, Jordi Romero‐Giménez et autres

Background: Histamine intolerance manifests when there is an imbalance between the production of histamine and the body’s capacity to metabolise it. Within the gastrointestinal tract, diamine oxidase (DAO) plays a pivotal role in breaking down ingested histamine. Insufficient levels of DAO have …

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Diamine Oxidase Interactions with Anti-Inflammatory and Anti-Migraine Medicines in the Treatment of Migraine

Yaiza Tobajas, Marc Alemany-Fornés, Iris Samarra, Jordi Romero‐Giménez et autres

Histamine intolerance arises when there is a disparity between the production of histamine and the body's ability to break it down. In the gastrointestinal tract, the primary enzyme responsible for metabolizing ingested histamine is diamine oxidase (DAO), and a shortage of this …

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A specific combination of Mobilee® with whey protein promotes muscle regeneration in cultured myocytes

Xavier Escoté, Daniel Martinez-Puig, Yaiza Tobajas, P. Sentís et autres

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Potential therapeutic implications of histidine catabolism by the gut microbiota in NAFLD patients with morbid obesity

Sergio Quesada‐Vázquez, Anna Castells‐Nobau, Jèssica Latorre, Núria Oliveras‐Cañellas et autres

The gut microbiota contributes to the pathophysiology of non-alcoholic fatty liver disease (NAFLD). Histidine is a key energy source for the microbiota, scavenging it from the host. Its role in NAFLD is poorly known. Plasma metabolomics, liver transcriptomics, and fecal metagenomics were …

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Interaction of Diamine Oxidase with Psychostimulant Drugs for ADHD Management

Yaiza Tobajas, Marc Alemany-Fornés, Iris Samarra, Jordi Romero‐Giménez et autres

Histamine intolerance occurs when there is an imbalance between histamine production and the capacity for histamine degradation. Diamine oxidase (DAO) is the main enzyme for the catabolism of ingested histamine degradation in the gastrointestinal tract and its deficiency has been linked to …

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Pomegranate natural extract Pomanox® positively modulates skin health-related parameters in normal and UV-induced photoaging conditions in Hs68 human fibroblast cells

Roger Mariné-Casadó, Joan Teichenne-Jané, Yaiza Tobajas, Antoni Caimari et autres

Skin photoaging is primarily caused by ultraviolet radiation and can lead to the degradation of skin extracellular matrix components, resulting in hyperpigmentation and skin elasticity loss. In this area, polyphenols have become of great interest because of their antioxidant, anti-inflammatory and antiaging …

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