Accès ouvert
2022
preprint
OpenAlex
Don Steiner, Edmund J. Gosselin, David R. Nalin
Five-day-old mouse pups were fed either Prevnar 13 alone or peripheral blood mononuclear cells (PBMCs) isolated from adult donors and pulsed _ex vivo_ with Prevnar-13. Mice vaccinated with Prevnar-13 or with vaccine-pulsed PBMCs displayed a positive serum IgM response greater than that …
us
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Accès ouvert
2022
preprint
OpenAlex
Don Steiner, Edmund J. Gosselin, David R. Nalin
Five-day-old mouse pups were fed either Prevnar 13 alone or peripheral blood mononuclear cells (PBMCs) isolated from adult donors and pulsed _ex vivo_ with Prevnar-13. Mice vaccinated with Prevnar-13 or with vaccine-pulsed PBMCs displayed a positive serum IgM response greater than that …
us
(code pays fourni par la source)
Accès ouvert
2022
book
OpenAlex
David R. Nalin
Cholera remains a global threat in the 21st century, chiefly due to the continued lack of adequate resource provision and the political will to ensure a safe potable water supply and sanitary waste disposal for a burgeoning global population. The current Special …
Accès ouvert
2022
erratum
OpenAlex
David R. Nalin
In the original publication [...].
us
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Accès ouvert
2022
article
OpenAlex
David R. Nalin
To the Editor—Cholera control requires reduction of mortality rates along with vaccination programs. The article by Sack et al [1], contrasting cholera epidemiology in Bangladesh and Africa, describes possible strategies for cholera elimination by 2030. While most African outbreaks were short, high …
us
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Accès ouvert
2022
article
OpenAlex
David R. Nalin
Impressive advances have been made in new cholera vaccine development and vaccination control strategies [...].
us
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Accès ouvert
2022
article
OpenAlex
David R. Nalin
The "bench to bedside" (BTB) paradigm of translational medicine (TM) assumes that medical progress emanates from basic science discoveries transforming clinical therapeutic models. However, a recent report found that most published medical research is false due, among other factors, to small samples, …
us
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2021
article
OpenAlex
David R. Nalin
Accès ouvert
2021
article
OpenAlex
David R. Nalin
The original studies demonstrating the efficacy of oral glucose-electrolytes solutions in reducing or eliminating the need for intravenous therapy to correct dehydration caused by acute watery diarrheas (AWD) were focused chiefly on cholera patients. Later research adapted the oral therapy (ORT) methodology …
us
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Accès ouvert
2020
article
OpenAlex
David R. Nalin
TO THE EDITOR—In the excellent summary by Graepel et al [1] regarding the need to balance expediency and scientific rigor in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine development, there is one additional aspect that merits urgent research attention and funding, …
us
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Accès ouvert
2020
article
OpenAlex
Farzana Afroze, Steven Bloom, Paul Bech, Tahmeed Ahmed et autres
Background: Cholera remains a major global health problem, causing high output diarrhea leading to severe dehydration and shock in developing countries. We aimed to determine whether vasoactive intestinal polypeptide (VIP), the mediator of pancreatic cholera syndrome, has a role in the pathophysiology …
bd, gb, us
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2019
article
OpenAlex
David R. Nalin
us
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