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Lori M. Laffel, Thomas Danne, Georgeanna J. Klingensmith, William V. Tamborlane et autres
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Dattaraj Satish Sinai Sukhthanker, Yvonne Menezes, Bhagyashri Ramnath Kanekar, Minu George
Introduction: Spinal anaesthesia is a preferred choice for infraumbilical surgery. Various drugs have been added intrathecally to augment analgesia in the postoperative period. Morphine an opiate was among the first to be introduced. More recently the alpha-2 agonist Clonidine. Aim: To compare …
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Piers R. Blackett, Minu George, Don P. Wilson
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Piers R. Blackett, K P Farrell, Minh Truong, Minu George et autres
The feasibility of "point-of-care" screening for ideal cardiovascular health was explored in a pediatric specialty clinic setting. Children and adolescents aged 9-18 years (n=91) with treated and stabilized diseases were recruited at a pediatric endocrinology clinic. A table-top device was used to …
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Minu George, Alejandro Ruiz‐Elizalde, Joni Beck
### Adverse Event Our patient was 13 years and 2 months old, a white boy with type 1 diabetes diagnosed 2 years and 5 months before this adverse event (AE). He had no other significant medical history. His A1C was 7.6% 1 …
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Amena Sadiya, Solafa M. Ahmed, Martin Carlsson, Yohannes Tesfa et autres
OBJECTIVES: To study the effect of Vitamin D3 supplementation on metabolic control in an obese type 2 diabetes Emirati population. METHODS: This randomized double-blind clinical trial was conducted with 87 vitamin D-deficient obese, type 2 diabetic participants. The vitamin D-group (n=45) and …
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Minu George, Kenneth C. Copeland
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Anil Mongia, Risa Vecker, Minu George, Hanan Tawadrous et autres
BACKGROUND: The mineralocorticoid receptor is protected from excess of glucocorticoids by conversion of active cortisol to inactive cortisone by enzyme 11β-hydroxysteroid dehydrogenase type 2 present in the kidney. The metabolites of cortisol and cortisone are excreted in the urine as tetrahydrocortisol (5αTHF+5βTHF) …
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Ovidiu Galescu, Minu George, Sudhakar Basetty, I Predescu et autres
Background. Blood pressure (BP) percentiles in childhood are assessed according to age, gender, and height. Objective. To create a simple BP/height ratio for both systolic BP (SBP) and diastolic BP (DBP). To study the relationship between BP/height ratios and corresponding BP percentiles …
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Minu George, Sunil Sinha, Irene Mamkin, Pascal Philibert et autres
AIMS: 17-β-Hydroxysteroid dehydrogenase type 3 (17βHSD-3) is expressed exclusively in the testes where it converts Δ4 androstenedione (Δ4) to testosterone (T). Here, we report a patient with a rare mutation at a critical site in HSD17B3 gene leading to deficiency of 17β …
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Minu George, Maria I. New, Svetlana Ten, Charles Sultan et autres
17-β-Hydroxysteroid dehydrogenase type 3 (17βHSD-3) deficiency is a rare, but frequently misdiagnosed autosomal recessive cause of 46,XY disorder of sex development (DSD). 17βHSD-3 enzyme is present almost exclusively in the testes and converts Δ4-androstenedione (Δ4) to testosterone (T). The diagnosis can be …
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