Kazeem Aderogba

Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT)

Nicholas Iain Paton, Alejandro Arenas‐Pinto, Wendy S. Hadley, David Stacey et autres

Background: Treatment-simplification strategies are important tools for patient-centred management. We evaluated long-term outcomes from a PI monotherapy switch strategy. Methods: Eligible participants attending 43 UK treatment centres had a viral load (VL) below 50 copies/ml for at least 24 weeks on combination …

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Attitudes to disclosure of HIV-serostatus to new sexual partners and sexual behaviours among HIV-diagnosed gay, bisexual and other men who have sex with men in the UK

Marina Daskalopoulou, Alison J. Rodger, Andrew N. Phillips, Richard J.C. Gilson et autres

We assessed attitudes to disclosure to new sexual partners and association with sexual behaviours among HIV-diagnosed gay, bisexual, and other men who have sex with men (GBMSM) in the UK Antiretrovirals, Sexual Transmission Risk and Attitudes (ASTRA) study in 2011-12. Among 1373 …

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Developing and testing accelerated partner therapy for partner notification for people with genitalChlamydia trachomatisdiagnosed in primary care: a pilot randomised controlled trial

Claudia S. Estcourt, Lorna J. Sutcliffe, Andrew J Copas, Catherine Heather Mercer et autres

BACKGROUND: Accelerated partner therapy (APT) is a promising partner notification (PN) intervention in specialist sexual health clinic attenders. To address its applicability in primary care, we undertook a pilot randomised controlled trial (RCT) of two APT models in community settings. METHODS: Three-arm …

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CAN ACCELERATED PARTNER THERAPY (APT) IMPROVE OUTCOMES OF PARTNER NOTIFICATION FOR WOMEN DIAGNOSED WITH GENITAL CHLAMYDIA IN PRIMARY CARE SETTINGS: A PILOT RANDOMIZED CONTROLLED TRIAL IN GENERAL PRACTICE AND COMMUNITY SEXUAL HEALTH SERVICES

Claudia S. Estcourt, L Sutcliffe, Catherine Heather Mercer, Andrew J Copas et autres

The ‘Antiretrovirals, Sexual Transmission Risk and Attitudes’ (ASTRA) Study. Design, Methods and Participant Characteristics

Andrew Speakman, Alison J. Rodger, Andrew N. Phillips, Richard J.C. Gilson et autres

Life expectancy for people diagnosed with HIV has improved dramatically however the number of new infections in the UK remains high. Understanding patterns of sexual behaviour among people living with diagnosed HIV, and the factors associated with having condom-less sex, is important …

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Neurocognitive Function in HIV Infected Patients on Antiretroviral Therapy

Alan Winston, Alejandro Arenas‐Pinto, Wolfgang Stöhr, Martin Fisher et autres

OBJECTIVE: To describe factors associated with neurocognitive (NC) function in HIV-positive patients on stable combination antiretroviral therapy. DESIGN: We undertook a cross-sectional analysis assessing NC data obtained at baseline in patients entering the Protease-Inhibitor-Monotherapy-Versus-Ongoing-Triple therapy (PIVOT) trial. MAIN OUTCOME MEASURE: NC testing …

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ART use, viral suppression, and sexual behaviour among HIV‐diagnosed MSM in the UK: results from the Antiretrovirals, Sexual Transmission Risk and Attitudes (ASTRA) Study

Fiona C. Lampe, Andrew Speakman, Andrew N. Phillips, Lorraine Sherr et autres

Objective To assess the associations of ART use, viral load (VL) suppression and transmission risk beliefs with sexual behaviour among HIV‐diagnosed men who have sex with men (MSM) in the UK. Methods ASTRA is a multicentre UK study of >3000 HIV outpatients …

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A hat trick of ulcerating pathogens in a single genital lesion

Miriam Samuel, Kazeem Aderogba, Nilesh C Dutt, John Shearer Lambert et autres

We report on a patient from a London clinic, (a Jamaican heterosexual man known to have herpes) who has donovanosis and syphilis in a single genital ulcer. The case highlights the importance of careful clinical examination of genital ulcers.

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