Ramiro Esteban Llovera

Growth hormone secretagogue receptor and cannabinoid receptor type 1 intersection in the mouse brain

Camila Saenz, Gimena Fernández, Ramiro Esteban Llovera, María José Tolosa et autres

The growth hormone secretagogue receptor (GHSR) and the cannabinoid receptor type 1 (CB1R) are G-protein coupled receptors highly expressed in the brain and involved in critical regulatory processes, such as energy homeostasis, appetite control, reward, and stress responses. GHSR mediates the effects …

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The Concentration of Liver-Expressed Antimicrobial Peptide 2 in Human Milk and Infant Plasma Is Positively Associated with Adiposity and Body Weight in the First Year of Life

Ana Luz Kruger, Agustina Malpeli, Marisa Sala, Carla Casado et autres

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Nanoformulation for potential topical delivery of Vismodegib in skin cancer treatment

Camilo Febres-Molina, Ramiro Esteban Llovera, Christian Zevallos Delgado, María Eugenia Tuttolomondo et autres

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Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity

Jimena Ricatti, Laura Acquasaliente, Giovanni Ribaudo, Vincenzo De Filippis et autres

The mouse Major Urinary Proteins (MUPs) contain a conserved β-barrel structure with a characteristic central hydrophobic pocket that binds a variety of volatile compounds. After release of urine, these molecules are slowly emitted in the environment where they play an important role …

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Ghrelin binding to serum albumin and its biological impact

Daniela Lufrano, Stephen J. Trejo, Ramiro Esteban Llovera, Mariano Salgueiro et autres

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Biochemical, biophysical, and functional properties of ICA512/IA-2 RESP18 homology domain

Laura Mercedes Sosa, Juha M. Torkko, María E. Primo, Ramiro Esteban Llovera et autres

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DETECCIÓN NO INTRUSIVA DE AGUA MEDIANTE DISPERSIÓN DE NEUTRONES DE FUSIÓN NUCLEAR

Ramiro Esteban Llovera, Aureliano Tartaglione, Alejandro Clausse, Cesar H. Moreno

Se presenta un método no intrusivo de detección de agua basado en la medición simultánea en dos direcciones de los neutrones de fusión emitidos al colapsar una lámina de plasma denso magnetizado. Como fuente de neutrones se utiliza un plasma focus de …

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P1‐489: Insulin‐degrading enzyme: A possible “dead‐end” chaperone for amyloid peptides

Matías B. de Tullio, Agata C. Fernandez Gamba, Ramiro Esteban Llovera, Laura Morelli et autres

Insulin-degrading enzyme (IDE) is central to the turnover of insulin and amyloid β (Aβ) in the mammalian brain and its reduced activity may contribute to the development of sporadic Alzheimer's disease (AD). Wild type rat IDE and the inactive mutant IDE-E111Q were …

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The Catalytic Domain of Insulin-degrading Enzyme Forms a Denaturant-resistant Complex with Amyloid β Peptide

Ramiro Esteban Llovera, Matías de Tullio, Leonardo Gabriel Alonso, Malcolm A. Leissring et autres

Insulin-degrading enzyme (IDE) is central to the turnover of insulin and degrades amyloid beta (Abeta) in the mammalian brain. Biochemical and genetic data support the notion that IDE may play a role in late onset Alzheimer disease (AD), and recent studies suggest …

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Insulin-degrading enzyme degrades amyloid peptides associated with British and Danish familial dementia

Laura Morelli, Ramiro Esteban Llovera, Leonardo Gabriel Alonso, Blas Frangione et autres

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Insulin-degrading Enzyme in Brain Microvessels

Laura Morelli, Ramiro Esteban Llovera, Irina Mathov, Lih‐Fen Lue et autres

The accumulation of amyloid beta (Abeta) in the walls of small vessels in the cerebral cortex is associated with diseases characterized by dementia or stroke. These include Alzheimer's disease, Down syndrome, and sporadic and hereditary cerebral amyloid angiopathies (CAAs) related to mutations …

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P1-177 Insulin degrading enzyme from human brain microvessels degrades amyloid β and its flemish, Dutch and Italian vasculotropic variants

Laura Morelli, Ramiro Esteban Llovera, Blas Frangione, Jorge A. Ghiso et autres